<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06053

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSVSLSDFEAKVKNLFKEHAKSGIAHFFFRPYLITSSEEYEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANRIVDFFVRNVTQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFMENISLLDYKGVRDTLKRLLDIPIPVHLQVDQRKSVEAVEKRMADCFTEIIESFRPLAQLNSVCGRTFMTPIPGHVGFYFNAFWKLEALSLRFPLKGLLPYSQDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSVEEFAVILDLYRLLYTGRDIFTVSGSDSSCVLMLAPTCIWIHILKKSPSMEVELPPTVNTQRKFLQEALKNKTQFNTDNYMVAVLCNAYSSTSEIFQQDLLPILLENLDNTRGHNSTQASGNFASNATSSMPYPNGAVSEVKLRPLKLEFLDSVSVHVRMNIANSLIGTFGRFMQGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMYRYHYYYYFVGCLFGAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISNCDSCFIEGVYRELLNKLPSYSWPQSTLSVFPQVFCSHYTQQQQQQQQQQQQQQQQQQQQPQQPQQQQQPQPQQSNVVVGSSQQPQQQQQSRFLLKQQVDEEYIKHRTFGSELSLIDYFTNTSTSTVYLCLLWRLVYDTGELPAVSMKILEVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERNWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSINTDVSNKLDFEKRSKLMEDCYAARILALCHAVWLHSTSGYLQLLPQALRSTWIPHVRSEEQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSVGKGSFEEDFTSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPVMTFSLYFPALFPFFGTAALDMVIVGAFSEISNCILKWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSVSRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVAFIPIGRLPTALFYGMLFVEHFFCFFTTAVLLPVLFTNNSNKLQ
Length1715
PositionTail
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.12
Grand average of hydropathy0.077
Instability index46.24
Isoelectric point7.24
Molecular weight196922.81
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06053
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.03|      20|      20|     726|     745|       1
---------------------------------------------------------------------------
  726-  745 (40.95/28.29)	QQQQQQQQQ...QQQQQPQQPQQ
  747-  769 (36.07/23.97)	QQPQPQQSNvvvGSSQQPQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     293.61|      64|      86|    1531|    1594|       2
---------------------------------------------------------------------------
 1417- 1479 (78.29/44.65)	...YFPALFPffgtaalDMVIVGAFSEISNCILKWILLDDRPYWWVH.....TAGVSGQLS.HPLKQFqWTC
 1499- 1527 (27.02/10.52)	NLLY...NLQ.......SDLVLGDLCGICWLLYVVFLIA.................................
 1531- 1594 (102.18/60.55)	SRTYISAHFP.......DQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRF.FGV
 1616- 1676 (86.12/49.86)	STTPLASFFR.......D...VGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVAF.IPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     207.74|      72|      86|      83|     166|       3
---------------------------------------------------------------------------
   83-  166 (97.29/92.86)	RIVDFFVRNVTQ.RQMLSIKCICEK.LLTCAELNInscGWndTF.AFF.MENISLLDYKGvRDTLKRLLdiPiPVHLQVdQRKsvEAV
  169-  227 (75.57/41.03)	RMADCFTEIIESfRPLAQLNSVCGRtFMTPIPGHV...GF..YFnAFWkLEALSL......RFPLKGLL..P................
  879-  910 (34.88/14.00)	...............................................F.MLTMLLRDYEG.NDAFYALL....IVMLLV.QRS..EEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.81|      21|      34|    1224|    1257|       4
---------------------------------------------------------------------------
 1057- 1078 (38.17/ 9.39)	WLLS.AEFVGWVGQATdRGPWVP
 1228- 1249 (36.65/36.15)	WLHStSGYLQLLPQAL.RSTWIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.72|      15|      85|     238|     252|       5
---------------------------------------------------------------------------
  238-  252 (28.85/14.03)	RLLTHVFMHYTYRDA
  320-  334 (28.86/14.03)	KILHTKLTHYPYRYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.84|      27|      40|     957|     993|       7
---------------------------------------------------------------------------
  967-  993 (48.34/37.45)	PVY.FGTRCLQML.PVVDLLLQKLVESPA
 1008- 1036 (41.49/15.37)	PLYrFHPYPVSFLySTFRFYEKRLVESPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.01|      23|     291|     293|     318|      12
---------------------------------------------------------------------------
  293-  318 (38.91/31.90)	NPQAWRIISTqiiY.....LTLQQSICFTRL
  585-  612 (36.10/21.36)	NYRLFNIPST...YrvhaiVTLQQTLAFAKF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06053 with Med23 domain of Kingdom Metazoa
Unable to open file!