<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06048

Description Aromatic-L-amino-acid decarboxylase
SequenceMDAEEFRKWGKKMIDFVADYWINLPSRTPMSDVKPGYLRSLLPEEAPMDPDSWENIFSDIETVILQGTTHWHHPLFFAYYPTGNSYPAILGDILSAGIGCIGFTWNSSPACTELEMVMMDWLAKLLKLPEYFLYSHSGPGAGMIQAHSSVERAAMLAHVQIRKVPSDENYRMTRVALQAVIENDINAGFIPFFVCATLGTTNSCAFDCLTEIGLLCKEKEIWLHIDAAYAGSAFICPEYRHLLDGIEYADTFNFNPHKALMINFDCSAMWFKNVLEIENAYYVNPQYLKHEHQNMIPDFRNWQIPLGRRFRSLKLWLTFRSLGVGFLQENIRKMCRLAKEFADFVVKDERFELVAPVILGLVCFRLKTRDSSGILRTKIALGRKPSVIMPFYMMKNELPSPSPITGSMNLLSYYGLDHAFNKFCNNKKLKEELSAFLPNLPANIFQIVNMYFLKFSSLRQLFEKPPICGKEILPLSNSDLAGFRLLPGSIPEEYQLWNVGAEIVNDKKKRKRKHELLSAGESAEDDVEKRLKRMKKEEEKKEKKKKKKDKKKKIIMSLTLFLCVCMISLSCFHESVFADPTPVVMWHGMGDTCCNLGSLGAIISVLEREIPGIYVLSLRFGNTSTEDIENSYFGNVNKQISDVCNQIANDEHLQNGYHAIGFSQGSQFLRAVAQRCPSPPMRNYISIGGQHQGVFGLPRCRGSIKLCNFARMLLNYGAYVHVIQAQYWHDPLHENTYRDKSIFLAEINNEKVLNQTYIENLQKLQNMVMIKFTRDSMVVPPESSWFGFYAPGQAVDVIPLKETELYKNDRLGLLQMEKDGKLHFLETNGDHLQFTEKYFISEIVNKFIK
Length849
PositionHead
OrganismTrichinella sp. T9
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.11
Grand average of hydropathy-0.204
Instability index45.36
Isoelectric point7.92
Molecular weight97277.60
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
carboxy-lyase activity	GO:0016831	IEA:InterPro
pyridoxal phosphate binding	GO:0030170	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
cellular amino acid metabolic process	GO:0006520	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06048
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.88|      10|     196|      71|      80|       2
---------------------------------------------------------------------------
   71-   80 (23.87/15.59)	WHHPLFFAYY
  728-  737 (23.00/14.74)	WHDPLHENTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.25|      48|     322|     425|     480|       4
---------------------------------------------------------------------------
  425-  480 (70.23/71.71)	NNKKLKEElsAFLPNLPanifQIVNMYFLKFSslRQLFEKPP........ICGK..EILPLSNSDL
  748-  805 (72.02/49.89)	NNEKVLNQ..TYIENLQ....KLQNMVMIKFT..RDSMVVPPesswfgfyAPGQavDVIPLKETEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      27.51|       8|      19|     299|     310|       6
---------------------------------------------------------------------------
  299-  310 (11.52/17.14)	FRnwqiPLGRRF
  319-  326 (15.99/ 7.63)	FR....SLGVGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.49|      18|      19|     493|     510|       7
---------------------------------------------------------------------------
  493-  510 (31.02/22.73)	EYQLWNVGAEIVNDKKKR
  513-  530 (28.47/20.25)	KHELLSAGESAEDDVEKR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06048 with Med19 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) YLRSLL
37
42