<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05995

Description "Serine--tRNA ligase, cytoplasmic"
SequenceMSVSLSDFEAKVKNLFKEHAKSGIAHFFFRPYLITSSEECEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANKIVDFFVRNVIQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFMENISLLDYKDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMYRYYYYYYYYFAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSKVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERTWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTLMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDNMNSINTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSTSGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPLCFHFLAPLRWIWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRFFGVDTHRSIELAAKYCHRAEWIHLSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVSLNQLVAFIPIGRLPTALFYAVLLPALIVLLLTMVLDLDNFRVEKGGNVQAVRVSQQKRFQSVDLVDQVVETDQEWRRSRYLSDEWNRLKNLCSKEIGEKIKRKEPVDGNSTLPDSLTDKLQKLTVDQIRALSVGQIKQLRLLIDHEMEKSYKLVENLEAVRFKALSQIGNLVHNSVPVSENEDDNEIVRTWGELEVRKKYSQVDLGIMVDGYDSERGCSVAGSRGYFLKGPLVFLEQALIQLAMHMLFKKKYTPLYTPFFMRKEVMQEVAQLSDFDDQLYKVIGKSSEVKEEIAEEEKYLIATSEQPIAAYHRDEWISKESLPLRYVGFSTCFRQEVGSHGRDTSGIFRVHQFEKVEQFCITSPHDDASWEMLEEMISNAEMFYQTLNIPYRVVSIVSGELNNAAAKKYDLEAWFPGSGAFRELVSCSNCTDYQSRRLRIRYGQTKKMMAKAEFVHMLNGTMCATTRTICAILENFQEENGIAVPEALRQYMPDDYKDFIPFVKPAPKVEQAAKRGGNKSATAEKSTQ
Length1736
PositionTail
OrganismTrichinella sp. T9
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.12
Grand average of hydropathy0.006
Instability index40.24
Isoelectric point7.36
Molecular weight199854.32
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
serine-tRNA ligase activity	GO:0004828	IEA:UniProtKB-EC

GO - Biological Process
seryl-tRNA aminoacylation	GO:0006434	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05995
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.32|      18|      34|    1104|    1136|       1
---------------------------------------------------------------------------
 1107- 1136 (26.67/42.81)	RRRWsnliafmialllIALSVHEVHRFF...GV
 1151- 1171 (29.65/11.89)	RAEW............IHLSTTPLASFFrdvGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.01|      29|      34|     787|     820|       2
---------------------------------------------------------------------------
  787-  820 (44.62/48.03)	RSKLMEDCYP.ARILALCHAVwlhstSGYLQLLPQ
  823-  852 (51.39/37.89)	RSTWIPHVRSeGQFLYVCHLV.....APFLQRFYQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.19|      53|      83|     103|     159|       3
---------------------------------------------------------------------------
  103-  159 (90.08/64.26)	ICEKLLT..CAELNINSCGWN..DTFAFFMENISLLDYKDLLnpqmRLLTHVFMHYTYRDA
  185-  241 (86.11/51.71)	ILELMFTaeCDHSQLNPQAWRiiSTQIIYLTLQQSICFTRLV....KILHTKLTHYPYRYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.41|      47|      81|     453|     502|       4
---------------------------------------------------------------------------
  453-  502 (77.00/65.69)	VPLERFMLT...MLLRDYEGNDAFYALLIVMLLVQRseeLRSAVADCVAMLPS
  531-  580 (78.41/58.25)	VELSRASLTpndCPLPVYFGTRCLQMLPVVDLLLQK...LVESPAACLKFLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.87|      16|      30|     276|     292|       6
---------------------------------------------------------------------------
  276-  292 (26.75/20.96)	CRMLtYPDLEILGLKQF
  306-  321 (34.12/22.08)	CEMM.YICCEILNYRLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.39|      14|      32|    1049|    1062|       7
---------------------------------------------------------------------------
 1049- 1062 (28.00/20.48)	DLVLGDLCGICWLL
 1084- 1097 (24.39/16.74)	QVILGIVVGICIAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.63|      28|      29|     960|     988|       9
---------------------------------------------------------------------------
  960-  988 (47.99/33.74)	FGETAQHFWLAVTKLGDPLCfHFLAPLRW
  992- 1019 (53.65/32.90)	LLDDRPYWWVHTAGVSGQLS.HPLKQFQW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     221.98|      70|     796|     855|     932|      11
---------------------------------------------------------------------------
  855-  932 (109.95/104.15)	TKfTMDITTDLYQMLYNVDCEVgnwkyEDLIC...DFFYHVKYMYVGDSVRQ....DTDRIIPMLRPSlqQKLRYISFAQGEQSA
 1653- 1729 (112.03/79.62)	TK.KMMAKAEFVHMLNGTMCAT.....TRTICailENFQEENGIAVPEALRQympdDYKDFIPFVKPA..PKVEQAAKRGGNKSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.50|      20|      29|      49|      70|      14
---------------------------------------------------------------------------
   49-   70 (28.11/32.05)	ANELMEIFTSlpQNLQESAFSI
   81-  100 (33.39/27.94)	ANKIVDFFVR..NVIQRQMLSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.56|      17|      26|    1463|    1479|      15
---------------------------------------------------------------------------
 1463- 1479 (30.62/20.36)	LYTPFFMRKEVMQEVAQ
 1487- 1503 (26.93/17.04)	LYKVIGKSSEVKEEIAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.86|      34|     832|     752|     785|      16
---------------------------------------------------------------------------
  752-  785 (61.86/38.11)	ISYMEPFYQT..ILTTLCSDNMNSINTDVSNKLDFE
 1585- 1620 (54.00/32.38)	ISNAEMFYQTlnIPYRVVSIVSGELNNAAAKKYDLE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05995 with Med23 domain of Kingdom Metazoa
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