<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05992

Description RNA polymerase II-associated protein 3
SequenceMSFVSHGIRRMPNDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSQLLNEEVFKIPDLLSDNNGQKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLGFHDLTTKLSYVASVRHNVNLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDALEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDVLNFLYGTAGIDWKSKTLRHCDLKTVLDKAKHVCSKDQVQRWDDLFRKHIETAINKNDNEEEASVETFPKFYPTRIYPLSRVSVNECSSALVFSELATKVVLLPFMQITTVKRHARERIWFYRRS
Length596
PositionMiddle
OrganismTrichinella sp. T9
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.453
Instability index41.45
Isoelectric point7.47
Molecular weight68449.51
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05992
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.24|      31|      32|     251|     282|       1
---------------------------------------------------------------------------
  251-  282 (52.70/38.33)	YVK.KDYEKAIMCYSRSISAD.PFRPVVYcNRAM
  284-  316 (46.54/28.10)	YLKlKNYAEAYADCSKALTFDsTYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     306.92|     106|     302|      74|     196|       2
---------------------------------------------------------------------------
   74-  196 (143.86/190.19)	KQISVQLVNVQVNDSQlLNEEVFKIPD..LLSDNNGQKASSSNNNNGKKLSlSCPKCsciiLRENHGEQVTVeKELPeLSLkADGTVDM..KTFT....EFVrvdDIYDF..ENIGFSRDSNGVQYllcaaCE
  378-  493 (163.06/143.15)	KPLKVIIVRDAVKKSH.FNSQQPALSDesNVTKQSEQKISDYKLNASIKIT.RIPKC....YAELRADWISI.KEEP.LAL.ADYILNIpcDCFSnllgEFL...DVLNFlyGTAGIDWKSKTLRH.....CD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.42|      37|     321|      14|      52|       3
---------------------------------------------------------------------------
   14-   52 (54.54/46.68)	DKNSNEAPQRIEELIGELQQLRKDIRLCFrGVDcSPEEQ
  338-  374 (62.87/42.31)	DPNNDIAKKELEEIISKVKPAENDPLLVY.PVE.NPDEK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05992 with Med9 domain of Kingdom Metazoa
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