<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05991

Description RNA polymerase II-associated protein 3
SequenceMSFVSHGIRRMPNDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSQLLNEEVFKIPDLLSDNNGQKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLGFHDLTTKLSYVASVRHNVNLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDALEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSDPQCSISCMERLELIGKAKRFDIVVLFLSHLKTVLDKAKHVCSKDQVQRWDDLFRKHIETAINKNDNEEEASVETFPKFYPTRIYPLSRVSVNECSSALVFSELATKVVLLPFMQITTVKRHARERIWFYRRS
Length621
PositionMiddle
OrganismTrichinella sp. T9
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.393
Instability index41.07
Isoelectric point7.46
Molecular weight71223.92
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05991
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.24|      31|      32|     251|     282|       1
---------------------------------------------------------------------------
  251-  282 (52.70/34.79)	YVK.KDYEKAIMCYSRSISAD.PFRPVVYcNRAM
  284-  316 (46.54/25.42)	YLKlKNYAEAYADCSKALTFDsTYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     391.25|     140|     302|      74|     244|       2
---------------------------------------------------------------------------
   78-  244 (190.51/253.40)	VQLVNVQVNDSQLlNEEVFKIPD..LLSDNNGQKASSSNNNNGKKLSlSCPKCsciiLRENHGEQVTVeKELPeLSLkADGTVDM..KTFTEFvrvddiydfenIGFSRDSNGVQYLLCA.........ACEIGPLGfhdlttKLSYVASVRHnVNLVML.......VRKERKDISEKD.AQK..ALFEK
  382-  544 (200.74/165.00)	VIIVRDAVKKSHF.NSQQPALSDesNVTKQSEQKISDYKLNASIKIT.RIPKC....YAELRADWISI.KEEP.LAL.ADYILNIpcDCFSNL...........LGEFLDGEFVANLLKAfmikvnsdpQCSISCME......RLELIGKAKR.FDIVVLflshlktVLDKAKHVCSKDqVQRwdDLFRK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.31|      23|     211|     333|     363|       3
---------------------------------------------------------------------------
  327-  349 (37.59/34.72)	ALEDFQHVLTL.DPNNDIAKKELE
  358-  381 (35.73/16.04)	AENDPLLVYPVeNPDEKEYQKPLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05991 with Med9 domain of Kingdom Metazoa
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