<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05989

Description One cut domain family member
SequenceMKAAAALVYTNKLISLNYMESLITDIHTGISGGPDACNGSASDAMMAELRQTRSPASAMGSLHDAGDFRSHAPAGYHTLNGRMSPSSVNVLGSVAPLGFGSVTYATLTPLQPLPPISTVTQIDKFSNNVGQGANGGGAGAGGGGGFTFVAQAPLSSFIGGCTPASNATQANSYNLNVKYDYDVKGSQYQMSPLTMQPSPPHVQQTSATAFNGYGAYHQRTQARSPKRADPVPKMQFDATAFDFDATGAGPLMSTPNGAAGQPPPTIQQQQQQQQQQQRQQQQQQQQQQQQQQQQQQQQQQQQQMALGRGGGGGGANGSGIGPGGHPADPSTSRPVKGKTTTGSTSAHHHHHHNGAASNGSANDLEEINTKELAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMLKWLQEPEFQRMSALRLAGMGNVEANFDAKLALALIGQARKAEEEARQSDLGYRQILSRLLLIVHDAQDFRPMKAARRNSISDRRLAAVEDGSAALRTCKRKEEQQQQGIHTPGPKKPRLVFTDIQRRTLQAIFKETKRPSKEMQVTIAQQLGLDVSTVANFFMNARRRGADRWKDNDSNGSRVSELSRVISKVKKIDEQHDPTWTDYYALLSSIIPSPADKLPLTSQWWSAFFKYFYFLLSGYFLFQCTFFFYLICTTKHIRGARF
Length692
PositionKinase
OrganismTrichinella sp. T9
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.602
Instability index56.81
Isoelectric point9.77
Molecular weight75763.22
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05989
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.14|      24|     166|     137|     168|       2
---------------------------------------------------------------------------
  137-  168 (35.20/40.43)	GAGaGGGGGftfvaqAPlSSFIG.GCTPASNAT
  307-  331 (46.95/27.13)	GRG.GGGGG......AN.GSGIGpGGHPADPST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.17|      29|      30|     204|     232|       4
---------------------------------------------------------------------------
  170-  199 (35.23/16.57)	...ANSYNlnvkyDYDVKGSQYQM.SPLTM..QPSP
  204-  232 (52.38/28.16)	QTSATAFN.....GYGAYHQRTQARSPKRA..DPVP
  235-  264 (47.56/24.90)	QFDATAFD......FDATGAGPLMSTPNGAagQPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.75|      15|      15|     361|     375|       5
---------------------------------------------------------------------------
  361-  375 (23.88/15.34)	ANDLEE..INTKELAQR
  377-  393 (19.88/11.67)	SAELKRysIPQAIFAQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.12|      25|      29|      50|      78|       7
---------------------------------------------------------------------------
   50-   78 (36.65/39.17)	RQTRSPASAMGSLHDAGdFrshAPAGYHT
   82-  106 (43.48/29.73)	RMSPSSVNVLGSVAPLG.F...GSVTYAT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05989 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YQMSPLTMQPSPPHVQQTSATAFNGYGAYHQRTQARSPKRADPVPKMQFDATAFDFDATGAGPLMSTPNGAAGQPPPTIQQQQQQQQQQQRQQQQQQQQQQQQQQQQQQQQQQQQQMALGRGGGGGGANGSGIGPGGHPADPSTSRPVKGKTTTGSTSAHHHHHHNGAASNGSANDLEEINTKELA
188
373










Molecular Recognition Features






MoRF SequenceStartStop




NANANA