<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05984

Description Coiled-coil domain-containing protein 47
SequenceMIMRMQEVDKNFINSVGGIVQNIKSIQSSISEVLAKLQMVDQPSLLNSFRVISSQFNSMLQLLRSDRASHFKNYVFLPIKLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRICNPESLQKQITAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDGEDTALLVAAILKGQNLRLLPHAEVVVIQGIQRQAKLNAVLFHIEKAVHGKECLIAKIRKKKTVGRKTCIWMFFLSCLFEFVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFTANNVNERETPPVDTASIGAKRSPAYAEQKLNDAPNNNFNDDDYGIVEDESVDDFSHLLDENEFENFPDERRPGKQNAGPSKTVTQLKITDVPGHLRNNWNNFVVELFLIFGLVVYTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDVIEIKIILNPEEMDPFVFALGTKRSAIKNSKEIMDLNLYCSEKKNVEKLGLPSSYILHSEIGEVTTGLIDTKIVSALCKYKDVVDYIHISDQFVGIKPIEMENMTKPPETAKCLTKCEYLVPGQLRATEEDVSSLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAMLRFLIKAKQIHC
Length739
PositionHead
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.424
Instability index41.68
Isoelectric point6.51
Molecular weight84858.36
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05984
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     256.64|      81|     229|     342|     428|       1
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  342-  428 (129.97/95.19)	VDDFSHLLDenEF.enfPDERRPGKQNAGPSKTVTQLKITdVPGHLRNNWNNF.VVELFLIFGLVVYTKNHSLAVAW.....FDSNRPFLEENF
  574-  664 (126.67/76.07)	VVDYIHISD..QFvgikPIEMENMTKPPETAKCLTKCEYL.VPGQLRATEEDVsSLQPLMIFIFHVLEKVRRFRLTRegkqkADKNRQYVEESF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.31|      17|      71|     154|     170|       2
---------------------------------------------------------------------------
  154-  170 (29.86/20.31)	DSLNASIRDSEMDGRKT
  227-  243 (29.45/19.94)	ECLIAKIRKKKTVGRKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.72|      32|      71|     430|     461|       3
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  430-  461 (57.59/31.64)	IVGDDGISPEV....TKNVLIKESDN..HYIVWCSGRQ
  498-  535 (45.13/23.49)	ILNPEEMDPFVfalgTKRSAIKNSKEimDLNLYCSEKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.90|      39|     581|     109|     149|       4
---------------------------------------------------------------------------
  109-  149 (62.23/41.30)	LRTKPDPQVEQK..DQQISNQVQQRicNPESLQKQITAFNRCL
  691-  731 (58.67/32.52)	LMAEEDPERQRKleKQELKRELKKK..QPRVKQIKIKAMLRFL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05984 with Med8 domain of Kingdom Metazoa
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