<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05981

Description Coiled-coil domain-containing protein 47
SequenceMIMRMQEVDKNFINSVGGIVQNIKSIQSSISEVLAKLQMVDQPSLLNSFRVISSQFNSMLQLLRSDRASHFKNYVFLPIKLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRICNPESLQKQITAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDGEDTALLVAAILKGQNVKPAYSATPASSRGSSGDSGHSKASKAQVRIATTHHPCCFILKKQCMAKNKCSININQFTTERRKTCIWMFFLSCLFEFVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFTANNVNERETPPVDTASIGAKRSPAYAEQKLNDAPNNNFNDDDYGIVEDESVDDFSHLLDENEFENFPDERRPGKQNAGPSKTVTQLKITDTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDVIEIKIILNPEEMDPFVFALGTKRSAIKNSKEIMDLNLYCSEKKNVEKLGLPSSYILHSEIGEVTTGLIDTKIVSALCKYKDVVDYIHISDQFVGIKPIEMENMTKPPETAKVVMICLNIPGQLRATEEDVSSLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAMLRFLIKAKQIHC
Length727
PositionHead
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.496
Instability index43.58
Isoelectric point6.61
Molecular weight83033.89
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05981
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.45|      55|     212|      71|     127|       1
---------------------------------------------------------------------------
   71-  127 (88.74/70.78)	FKNYVFLPIKLSVEVDADLEAATENRLHawTHAVVPDYLRTKPDPQ.VEQKDQQISNQ
  286-  341 (87.71/61.99)	FAEFEEFDVELDASVDADFTANNVNERE..TPPVDTASIGAKRSPAyAEQKLNDAPNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     138.20|      36|      36|     523|     558|       3
---------------------------------------------------------------------------
  500-  520 (26.59/14.63)	......LGTKRSAIKNSK...EI....MDLNL...YC
  523-  558 (57.34/39.79)	KKNVEKLGLPSSYILHSEI.GEVTTGLIDTKIVSALC
  561-  597 (54.27/37.27)	KDVVDYIHISDQFVGIKPIeMENMTKPPETAKVVMIC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.70|      34|      38|     357|     390|       4
---------------------------------------------------------------------------
  357-  390 (61.32/35.92)	DDFSHLLDENEFE.NFP..DERRPGKQNAGPSKTVTQ
  395-  431 (51.38/29.04)	DTKNHSLAVAWFDsNRPflEENFSIVGDDGISPEVTK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05981 with Med8 domain of Kingdom Metazoa
Unable to open file!