<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05979

Description ADP-ribosylation factor-like protein 5B
SequenceMNDRSNLVSSFPAPPIHYISQCTDSNIKDNLILPPPPPIHGAYTMFGVQYNTEDMIIQPLENQGIRRLYPNTPNFDRKVELKKLNHSIIANFLDLLEILIRCPSSPERERKIEDLSLLFINFHHLVNEFRPHQACQSLMLMLERQYKERMCYVNHFRDHFQAVEENLSNCLDNFPDQLEIKFLNDPTLKKIWIDCMQKSHMKRSESEKSIRFSVERKPMGLLVTKLWRWLFNNQEHKVIIVGLDNAGKTTILYHFLMDEVVHTSPTIGSNVEEVVWKNIHFLMWDIGGQDSLRASWNTYYTNTEFVILVIDSADRERLSTIKEEFYRMLAHEELRKSAVLIFANKQDIKKSMTSAEISHELNLTSIKDQRWQIQACCALTGEVYYRCAYATVRVKSTPPVVFTVLVCTLFHFKLFHMIYWIQINRQRGMTAQSLCIFVILTLNSCTATFWNWLITNPHDLETDISSSNLRHDSPVPSPSRPNYVVAKLHSKNSPRPRHKHHHISTTTPPPPPPLQTASISTAQLSRLDDRSSNDEPGQLTCHADRECPLNLFCDLHYGLCKPYKTEQEPCRSDSQCAIGYDCMFGRCTMAAKPGHKGARCTGNRDCLPGLCCARQHGDKVCKPKLQIGQSCFVPDGGLSYWLNELCPCDDGLVCALSPQSADPKSMKIDWFQLWTESNQLHCISIHSSSGR
Length691
PositionMiddle
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.09
Grand average of hydropathy-0.366
Instability index53.45
Isoelectric point7.71
Molecular weight79443.38
Publications









Function






Annotated function


GO - Cellular Component
extracellular region	GO:0005576	IEA:InterPro
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GTP binding	GO:0005525	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
multicellular organism development	GO:0007275	IEA:InterPro
negative regulation of Wnt signaling pathway	GO:0030178	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05979
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.83|      25|     472|       9|      42|       1
---------------------------------------------------------------------------
    9-   42 (45.53/38.71)	SSFPAPPIHYISQCTDsnikdnlilPPPPPIHGA
  493-  517 (52.30/27.87)	SPRPRHKHHHISTTTP.........PPPPPLQTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.00|      21|      23|     575|     596|       2
---------------------------------------------------------------------------
  575-  596 (37.17/25.91)	QCAIGYDCMFGRCTmAAKPGHK
  599-  619 (43.83/25.91)	RCTGNRDCLPGLCC.ARQHGDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.43|      11|      25|     126|     136|       3
---------------------------------------------------------------------------
  126-  136 (23.69/13.89)	VNEFRPH.QACQ
  153-  164 (17.75/ 8.76)	VNHFRDHfQAVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.36|      20|      23|     276|     297|       6
---------------------------------------------------------------------------
  254-  271 (24.28/13.67)	..HFLMDEVVHTSPTIGSNV
  278-  297 (37.68/31.17)	NIHFLMWDIGGQDSLRASWN
  302-  319 (21.40/ 7.51)	NTEFVILVIDSADRERLS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.78|      11|      30|      70|      80|       7
---------------------------------------------------------------------------
   70-   80 (21.47/12.85)	PNTPNFDRKVE
  103-  113 (20.31/11.77)	PSSPERERKIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.51|       8|      30|     533|     544|       8
---------------------------------------------------------------------------
  533-  544 (11.84/12.84)	NDEPgqltCHAD
  566-  573 (16.68/ 6.62)	EQEP....CRSD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05979 with Med7 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PRPRHKHHHISTTTPPPPPPLQTASISTAQLSRLDDRS
494
531










Molecular Recognition Features






MoRF SequenceStartStop




NANANA