<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05979

Description ADP-ribosylation factor-like protein 5B
SequenceMNDRSNLVSSFPAPPIHYISQCTDSNIKDNLILPPPPPIHGAYTMFGVQYNTEDMIIQPLENQGIRRLYPNTPNFDRKVELKKLNHSIIANFLDLLEILIRCPSSPERERKIEDLSLLFINFHHLVNEFRPHQACQSLMLMLERQYKERMCYVNHFRDHFQAVEENLSNCLDNFPDQLEIKFLNDPTLKKIWIDCMQKSHMKRSESEKSIRFSVERKPMGLLVTKLWRWLFNNQEHKVIIVGLDNAGKTTILYHFLMDEVVHTSPTIGSNVEEVVWKNIHFLMWDIGGQDSLRASWNTYYTNTEFVILVIDSADRERLSTIKEEFYRMLAHEELRKSAVLIFANKQDIKKSMTSAEISHELNLTSIKDQRWQIQACCALTGEVYYRCAYATVRVKSTPPVVFTVLVCTLFHFKLFHMIYWIQINRQRGMTAQSLCIFVILTLNSCTATFWNWLITNPHDLETDISSSNLRHDSPVPSPSRPNYVVAKLHSKNSPRPRHKHHHISTTTPPPPPPLQTASISTAQLSRLDDRSSNDEPGQLTCHADRECPLNLFCDLHYGLCKPYKTEQEPCRSDSQCAIGYDCMFGRCTMAAKPGHKGARCTGNRDCLPGLCCARQHGDKVCKPKLQIGQSCFVPDGGLSYWLNELCPCDDGLVCALSPQSADPKSMKIDWFQLWTESNQLHCISIHSSSGR
Length691
PositionMiddle
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.09
Grand average of hydropathy-0.366
Instability index53.45
Isoelectric point7.71
Molecular weight79443.38
Publications









Function






Annotated function


GO - Cellular Component
extracellular region	GO:0005576	IEA:InterPro
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GTP binding	GO:0005525	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
multicellular organism development	GO:0007275	IEA:InterPro
negative regulation of Wnt signaling pathway	GO:0030178	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05979
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.83|      25|     472|       9|      42|       1
---------------------------------------------------------------------------
    9-   42 (45.53/38.71)	SSFPAPPIHYISQCTDsnikdnlilPPPPPIHGA
  493-  517 (52.30/27.87)	SPRPRHKHHHISTTTP.........PPPPPLQTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.00|      21|      23|     575|     596|       2
---------------------------------------------------------------------------
  575-  596 (37.17/25.91)	QCAIGYDCMFGRCTmAAKPGHK
  599-  619 (43.83/25.91)	RCTGNRDCLPGLCC.ARQHGDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.43|      11|      25|     126|     136|       3
---------------------------------------------------------------------------
  126-  136 (23.69/13.89)	VNEFRPH.QACQ
  153-  164 (17.75/ 8.76)	VNHFRDHfQAVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.36|      20|      23|     276|     297|       6
---------------------------------------------------------------------------
  254-  271 (24.28/13.67)	..HFLMDEVVHTSPTIGSNV
  278-  297 (37.68/31.17)	NIHFLMWDIGGQDSLRASWN
  302-  319 (21.40/ 7.51)	NTEFVILVIDSADRERLS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.78|      11|      30|      70|      80|       7
---------------------------------------------------------------------------
   70-   80 (21.47/12.85)	PNTPNFDRKVE
  103-  113 (20.31/11.77)	PSSPERERKIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.51|       8|      30|     533|     544|       8
---------------------------------------------------------------------------
  533-  544 (11.84/12.84)	NDEPgqltCHAD
  566-  573 (16.68/ 6.62)	EQEP....CRSD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05979 with Med7 domain of Kingdom Metazoa
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