<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05970

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLKHGDSVQANASVAGGAFKGSPVKLLGQREEGTLKFDLSLFVNNVAKACEAMDAIESVVMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTPTPTPTPTTTTQPAITDNGVDTAGVAPVAADDRAIRIRIKLGSSVNEATILGGQEKKQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSRDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDSRRPIRRLPPVDRSMLDRLDEIPSPSKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRMLPSEMRQLHSRVLVKTTDGRQVLALPYVDIGLPDFLEYDNSPATTEQLISWEAIRW
Length593
PositionUnknown
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.03
Grand average of hydropathy-0.678
Instability index72.75
Isoelectric point7.72
Molecular weight63204.03
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05970
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.50|      20|      20|     261|     280|       1
---------------------------------------------------------------------------
  237-  259 (31.98/ 6.06)	SScsrPVPLPTAPASQPRHPPPP
  260-  279 (47.55/12.44)	QP...PLPPPSAPTPPPPPPPPP
  280-  300 (39.97/ 9.33)	PP..qSSPPPLPPSPPPPTPPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.42|      28|      72|     361|     388|       2
---------------------------------------------------------------------------
  361-  388 (50.20/19.53)	SR.........DD.....APSPALL.FSAVEHQQPSGGGG..GEV
  407-  440 (31.88/10.01)	QN.........QDhvvagSSSGACTsSSSVDSDTSSRSST..PSR
  441-  476 (32.34/10.24)	DKivrasddddDD.....AP.PRSG.PGTV..SSPSDGGGkpGLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.23|      13|      15|     487|     499|       3
---------------------------------------------------------------------------
  487-  499 (24.48/13.66)	PPVDR.SMLDRLDE
  503-  516 (18.75/ 8.79)	PSKSRvSSLKYLDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.43|      49|     203|     107|     155|       5
---------------------------------------------------------------------------
  107-  155 (82.53/43.87)	PTPTPTPTTTT....QPAITDNGVDTAGVAPVAADDRAIRIRIKLG.SSVN...EAT
  301-  357 (68.90/35.29)	PPPSTSPSLTTtssrPPKLKTTAQLVADLTKCYPEELLVNINTSIGvDSTNalqQAT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05970 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSRDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDSRRPIRRLPPVDRSMLDRLDEIPS
2) SKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRM
152
504
502
537










Molecular Recognition Features






MoRF SequenceStartStop




1) RLLIKKWRKLIS
2) SLKYLDDYS
3) VNKLELLEKYLAEDA
93
510
388
104
518
402