<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05966

Description Endoplasmic reticulum-Golgi intermediate compartment protein 3
SequenceMLNNIESEEEQRIRFQVELEFVQCLANPNYLNYLAQRDFFKNPAFINYLKYLLYWKRQEYAKYLKFPQCLHILELLQTEEFRTAMTRVPNSKFLEDQMLLQWQFYIRKRVRAHNGVRLPSRCETCKYLALELEARFSETGQSPENTFNGRGGTKKYRDSELRFIETMENLCDRLLDYNLHKEHKNSLRFARGQSETMKTLHGLVNRGVQVELGLPYELWDSPSVEVTRMKQDCETMLENNEEAIERWYYAKQKEPLRHYLCENRVLNSDERECLYENQADSTPHTDLMLSQVIRQMRRLDAYSKPVEDFRIRTAFGGTVTLISSVVIGILFFNELMIYLSTEIVEELLVDTTVGDARLKINFDIVFPAMACILSVDAMDASGQFQNDVTENVWKEPIHWSENNVGTTMPTVQQSKAANCGSCYGAETSEIQCCNSCDDVIKAYKRKGWALNSMDSVEQCRDREWVQKLHHSLNQGCHVYGWLEVSKVTGNFHIAPGSSVKDVHVHVHNLHQLGPSAFNTSHTIKHFSFGESFPGKKFPLDGETVIANKGERTV
Length553
PositionMiddle
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.490
Instability index46.48
Isoelectric point6.02
Molecular weight64197.14
Publications









Function






Annotated function

Possible role in transport between endoplasmic reticulum and
Golgi. 


GO - Cellular Component
endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0033116	IEA:UniProtKB-SubCell
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05966
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      14|      15|     434|     448|       1
---------------------------------------------------------------------------
  434-  448 (23.03/22.16)	NSCDDVIKAYKRKgW
  451-  464 (28.16/20.67)	NSMDSVEQCRDRE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.30|      20|      20|      26|      45|       2
---------------------------------------------------------------------------
   26-   45 (37.66/26.59)	ANPNYL..NYL...AQRDFFKNPAF
   47-   66 (18.88/ 9.66)	...NYL..KYLlywKRQEYAKYLKF
   89-  105 (16.77/ 7.76)	PNSKFLedQML...LQWQFY.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.54|      17|      24|     135|     158|       3
---------------------------------------------------------------------------
  121-  145 (23.48/29.68)	RCETCKYLAleleaRFSETgqsPEN
  150-  169 (28.06/12.20)	RGGTKKYRD..selRFIET...MEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.04|      10|      20|     278|     287|       4
---------------------------------------------------------------------------
  278-  287 (18.51/11.79)	QADSTPHTDL
  300-  309 (18.54/11.82)	DAYSKPVEDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.89|      13|      20|     490|     503|       5
---------------------------------------------------------------------------
  490-  503 (19.71/18.40)	NFH.IAPgSSVKDVH
  508-  521 (20.18/12.50)	NLHqLGP.SAFNTSH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05966 with Med31 domain of Kingdom Metazoa
Unable to open file!