<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05965

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTTAVHSQIAQREFRDKLIAVKEEMTFYLQEAEQEYYNTALMKLFSVFEIECLRIKMTLDEFGTELYLDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNTDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSYEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVSVYLVDFGLHYCHFVDSGYVVLFCGYSTLWPMNCRSDSKLVHSAGADASLPLRVFIKSLFYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSSTAMYLAATAGMRILEIRDPLSSCKIINAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINSSEFTERNYSLKLFGETYNLFVDSYLCCGANEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRYMLDTSACSVKKAKIPKPRGEFMAFSGMYWTAKFFNCTSGCSYNKFFENVQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYRFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCIVFIVGCVFIIFALYRKFH
Length1071
PositionHead
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.11
Grand average of hydropathy-0.115
Instability index36.06
Isoelectric point5.82
Molecular weight121810.98
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05965
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     565.82|     172|     175|      13|     186|       1
---------------------------------------------------------------------------
   13-  172 (236.12/192.99)	..................AML..LKEYQVLLQRSVKSIRENFTEIIR..MAKVGEE.GQVSR.LTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQF.LILNDFAYINESITTTAVHSQIAQREFRDK.LIAVKEEMTFyLQEAEQ..EYYNTA..LMKLFSVFEIECLRIKMTLDEfGTELYLDPWQT
  173-  347 (228.32/175.55)	FVSIKGKLRKRAFRspnlAEV..VKDYDALASRLLDENCTEYSALCRmnMAKCKNQlGNTDQeAVEY.RTAGRLYIRAEKEKESVENRLSM.....EC.LYMAMHCY.NEAIR...LHLSQGQKLLAASlLIELGKELAC.MQHPEDaiQNFEKAihLLDTHPHAVGHALRWKLCVET.SVGFLADARRT
  351-  455 (101.37/72.21)	YRQIVESWPNSGFR...kLHLneLEIITVMLLLALKPIKSEMNDFEKrvLQRYSDE.TDEAL.LSSYEGSLLP......NDSYIIS..VEIYLHLKSFvLAINNNDPSAADIALTAIH........................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.26|      24|      26|     837|     861|       2
---------------------------------------------------------------------------
  837-  861 (40.50/31.13)	IIQAQI.VAEDTTNQQPlHPCL.PLNY
  865-  888 (37.24/23.52)	VTSEQIfLMPCSLNQKP.NNVL.P.NY
  889-  905 (18.52/ 7.99)	.......VFRGSSD..P.HSCLkKIRY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.31|      19|      21|     502|     520|       3
---------------------------------------------------------------------------
  502-  520 (30.66/20.22)	SAGADASLPLRVFIKSLFY
  526-  544 (30.64/20.20)	SLEVDSDFKVRDVINAYAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     191.34|      61|     256|     733|     798|       4
---------------------------------------------------------------------------
  733-  798 (99.03/68.30)	SNTMHSYNFLFKNASI.....ISGIDEGIYGWiTLNFlshrLMNSASKLNDIRPLT.IGAMDLGGAST..QIIF
  987- 1055 (92.31/51.89)	SLTLFKDAYRFSDAQIqkiefVNEIDSTEIGW.TLGF....MLNATNQLPEEQPIEhIGLIEFSLITTicCIVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.64|      23|     346|     457|     484|       5
---------------------------------------------------------------------------
  457-  484 (36.20/37.02)	RNVSVYLvdFGLHYCHFVDSgYvvLFCG
  808-  830 (48.44/29.17)	RNYSLKL..FGETYNLFVDS.Y..LCCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.76|      32|      47|     570|     602|       6
---------------------------------------------------------------------------
  570-  602 (54.40/40.90)	VLHVL.GIYNDEELIIsVRGEDSRRSRNSWWWLG
  618-  650 (52.36/34.62)	VLFALsGDLPDEFGII.IDAGSSHSGLYIYTWNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.85|      25|      50|     908|     933|       7
---------------------------------------------------------------------------
  908-  933 (43.61/30.56)	DTSACSVKK..................AKIPKPRgEFMA...FSGMY
  941-  986 (33.25/17.96)	CTSGCSYNKffenvqnycekswssieaAAYPYKK.TFLStycFTGLY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05965 with Med22 domain of Kingdom Metazoa
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