<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05954

Description Forkhead box protein A2-A
SequenceMLLHSDYGHHHSGASDPNSALTYGTSTLGQAAAAAAVAGYSVQAHPSAGIGSYANLSANMNASALNNPYSNMPSFTGMNSMGGHHTLNGYGSMPSMASTMSSLTMGPSAMGSSALSPIGRTQMQVGASTNVTPNNSSVVMGNSSTSLARGGNAKNTYRRSYTHAKPPYSYISLITMAIQQSNSKMLTLSEIYQFIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDCGNMFENGCYLRRQKRFKCEKRSGIAGSGGKGSRNASMSESGTFQAMVKVEEELEELQHHIQQQRSGQLNEASRGSPCEGTDSMQNHGVDLLTDERKIQPQDCAGNMLLISGDDDQQQQQQQQQQQQQQQQQQQQQQQKQQQQQQQQQQQHVSSALIAGSPSSHGNMLNANDMAGQSADTRHSTPNTLVTTTDGGALDVNLLQQAMAENNSPNSAGASCSSPRDSLVGVGSSSLANEGLAPVISYGASPNSLPQSAVYSSFGQLPPNYTHDPFGTLAFTHPFSITNLIDSSKPDSTYNLPNCYGNGSSTAAAQLSYNSLSPMMSQIGQSSAMSDSMPYYHTLYSSNNPGSAANL
Length598
PositionTail
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.06
Grand average of hydropathy-0.648
Instability index53.21
Isoelectric point6.54
Molecular weight64124.81
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro
protein domain specific binding	GO:0019904	IEA:InterPro
sequence-specific DNA binding	GO:0043565	IEA:InterPro
transcription factor binding	GO:0008134	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05954
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      15|      15|     360|     374|       1
---------------------------------------------------------------------------
  360-  374 (32.77/14.22)	QQQQQQQQQQQQQQQ
  376-  390 (31.89/13.70)	QQQQQQQKQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.34|      45|      49|     236|     284|       2
---------------------------------------------------------------------------
  236-  284 (73.68/48.43)	GSFWTLHPDCGNMFENGCYLRRQKRFKCEKRSgiAGSGGKGSrnASMSE
  286-  330 (77.65/40.43)	GTFQAMVKVEEELEELQHHIQQQRSGQLNEAS..RGSPCEGT..DSMQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     228.48|      49|      49|      17|      65|       3
---------------------------------------------------------------------------
   17-   59 (63.11/22.52)	........PNSA.L.TY.GTSTLGQAAAAAAVAGYSVQAHPSAGIGSYANLSAN
   60-   99 (49.78/16.41)	MNASALnnPYSN.MpSFtGMNSMG...GHHTLNGY..........GSMPSMAST
  100-  134 (50.85/16.90)	M..S........sL.TM.GPSAMG.SSALSPIGRTQMQ......VGASTNVTPN
  558-  598 (64.73/23.26)	LSYNSL....SP.M.....MSQIGQSSAMSDSMPYYHTLYSSNNPGSAANL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.66|      28|      28|     442|     469|       4
---------------------------------------------------------------------------
  410-  443 (33.18/12.34)	NMLN...A.NDMAG.QSADTRHSTPNTLvtttdggalD.V
  444-  471 (42.76/17.79)	NLLQQAMA.ENNSP.NSAGASCSSPRDS..........lV
  472-  501 (35.73/13.79)	GVGSSSLAnEGLAPvISYGASPNSLPQS.........A.V
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05954 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RSGIAGSGGKGSRNASMSESGTFQAMVKVEEELEELQHHIQQQRSGQLNEASRGSPCEGTDSMQNHGVDLLTDERKIQPQDCAGNMLLISGDDDQQQQQQQQQQQQQQQQQQQQQQQKQQQQQQQQQQQHVSSALIAGSPSSHGNMLNANDMAGQSADTRHSTPNTLVTTTDGGALDVNLLQQAMAENNSPNSAGASCSSPRDSLVGVGSS
266
476










Molecular Recognition Features






MoRF SequenceStartStop




1) SMPYYHTLYS
579
588