<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05940

Description RNA polymerase II-associated protein 3 (Fragment)
SequenceLKFICHLCHMVLDACQSDFVPVTLTNRLCALIRCDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSQLLNEEISNPSSDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSEPQCSISCMERLELIGKAKRFDIVVLFLGRTDFIYLKTVLDKAKHVCSKDQVQRWDDLFKKRIETAINKNDNEEEASVESFP
Length569
PositionMiddle
OrganismTrichinella murrelli
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.368
Instability index40.41
Isoelectric point5.75
Molecular weight64876.70
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW
GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05940
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.18|      31|      32|     250|     281|       1
---------------------------------------------------------------------------
  250-  281 (52.73/42.00)	YVK.KDYEKAIMCYSRSISADP.FRPVVYcNRAM
  283-  315 (46.46/30.71)	YLKlKNYAEAYADCSKALTFDStYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.31|      24|      32|      27|      52|       2
---------------------------------------------------------------------------
   27-   52 (37.70/26.88)	RLC.ALIRCdkNSNEAPQRIEELIGEL
   60-   84 (39.61/22.19)	RLCfRGVDC..SPEEQVHRVRVLYKEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     216.64|      73|     281|      95|     175|       3
---------------------------------------------------------------------------
   95-  175 (99.48/108.65)	KQISVQLVNVQVNDSQLLNEE..ISNPSSDVGPSTEKASSSNNNNGKKLSlSCPKCsciiLRENHGEQVTVeKELPeLSLkAD
  377-  451 (117.17/91.59)	KPLKVIIVRDAVKKSHFNSQQpaLSDESNVTKQSEQKISDYKLNASIKIT.RIPKC....YAELRADWISI.KEEP.LAL.AD
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05940 with Med9 domain of Kingdom Metazoa

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