<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05933

Description Endoplasmic reticulum-Golgi intermediate compartment protein 3
SequenceMLNNIESEEEQRIRFQVELEFVQCLANPNYLNYLAQRDFFKNPAFINYLKYLLYWKRQEYAKYLKFPQCLHILELLQTEEFRTAMTRVPNSKFLEDQMLLQWQFYIRKRVRAHNGVRLPSRCETCKYLALELEARFSETGQSPENTFNGRGGTKKYRDSELRFIETMENLCDRLLDYNLHKEHKNSLRFARGQSETMKTLHGLVNRGVQVELGLPYELWDSPSVEVTRMKQDCETMLENNEEAIERWYYAKQKEPLRHYLCENRVLNSDERECLYENQADSTPHTDLMLSQVIRQMRRLDAYSKPVEDFRIRTAFGGTVTLISSVVIGILFFNELMIYLSTEIVEELLVDTTVGDARLKINFDIVFPAMACILSVDAMDASGQFQNDVTENVWKEPIHWSEKNNVGTTMPTVQQSKATNCGSCYGAETSEIQCCNSCDDVIKAYKRKGWALNSMDSVEQCRDREWVQKLHHSLNQGCHVYGWLEVSKVTGNFHIAPGSSVKDVHVHVHNLHQLGPSAFNTSHTIKHFSFGESFPGKKFPLDGETVIANKGERQV
Length554
PositionMiddle
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.506
Instability index46.35
Isoelectric point6.10
Molecular weight64382.37
Publications









Function






Annotated function

Possible role in transport between endoplasmic reticulum and
Golgi. 


ECO:0000256	ARBA:ARBA00002776

GO - Cellular Component
endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0033116	IEA:UniProtKB-SubCell
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05933
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      14|      15|     435|     449|       1
---------------------------------------------------------------------------
  435-  449 (23.03/24.21)	NSCDDVIKAYKRKgW
  452-  465 (28.16/22.60)	NSMDSVEQCRDRE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.30|      20|      20|      26|      45|       2
---------------------------------------------------------------------------
   26-   45 (37.66/22.47)	ANPNYL..NYL...AQRDFFKNPAF
   47-   66 (18.88/ 8.05)	...NYL..KYLlywKRQEYAKYLKF
   89-  105 (16.77/ 6.43)	PNSKFLedQML...LQWQFY.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.54|      17|      24|     135|     158|       3
---------------------------------------------------------------------------
  121-  145 (23.48/30.99)	RCETCKYLAleleaRFSETgqsPEN
  150-  169 (28.06/12.92)	RGGTKKYRD..selRFIET...MEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.04|      10|      20|     278|     287|       4
---------------------------------------------------------------------------
  278-  287 (18.51/15.52)	QADSTPHTDL
  300-  309 (18.54/15.56)	DAYSKPVEDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.89|      13|      20|     491|     504|       5
---------------------------------------------------------------------------
  491-  504 (19.71/17.27)	NFH.IAPgSSVKDVH
  509-  522 (20.18/11.74)	NLHqLGP.SAFNTSH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05933 with Med31 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA