<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05925

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLFKQMQALPVERLKVRLLSCLDREKKVNNVAKACEAMDAIESVVMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTPTPTPTTTTQPAITDNGVDTAGVAPVAADDRAIRIRIKLGSSVNEATILGGQEKKQQQQQQQQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGNGGGSGETFSLASTVSKPCKPPRSSASCSRPVPLPSAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPTPPPPPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSREKIVRASDDDDDDAPPRPGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPSPGKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRMLPSEMRQLHSRVLVKTTDGRQVLALPYVDIGLPDFLEYDNSPATTEQLISWEAIRW
Length592
PositionUnknown
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.02
Grand average of hydropathy-0.735
Instability index74.17
Isoelectric point8.33
Molecular weight63421.48
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05925
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.18|      25|      27|     250|     274|       1
---------------------------------------------------------------------------
  236-  255 (37.72/ 7.24)	VPLPSAPASQPRHP.............PPPQPP
  256-  283 (55.57/14.25)	LPPPSAPTPPPPPPPPPPP.....qssPPPLPP
  284-  316 (51.89/12.81)	SPPPPTPTPPPPPPPPPPPstspslttTSSRPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.17|      13|      15|     486|     498|       2
---------------------------------------------------------------------------
  486-  498 (24.11/15.23)	PPVDR.SMLDRLDE
  502-  515 (18.05/ 9.34)	PGKSRvSSLKYLDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     261.53|      85|     251|      67|     160|       3
---------------------------------------------------------------------------
   67-  160 (122.39/95.74)	QLLhPDLAKrC...RLLIKkwrklISTTPTPTPTTTTQPAITDNGVDTAGvAPvAADDRAIRIRIKLGSSVNEATILGGQEKKQQQQQQQQQQQQQQ
  323-  410 (139.14/80.28)	QLV.ADLTK.CypeELLVN.....INTSIGVDSTNALQQATASNSGDDAP.SP.ALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.37|      15|      15|     446|     460|       4
---------------------------------------------------------------------------
  446-  460 (29.62/12.44)	SDDDDDDAPPRPGPG
  464-  478 (27.75/11.18)	SPSDGGGKPGLVDDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.40|      26|     203|     206|     234|       5
---------------------------------------------------------------------------
  206-  234 (34.38/26.39)	GGGSGETFSlASTVSKPCKpPRSSAScSR
  414-  439 (46.02/20.96)	GSSSGACTS.SSSVDSDTS.SRSSTP.SR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05925 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKQQQQQQQQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGNGGGSGETFSLASTVSKPCKPPRSSASCSRPVPLPSAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPTPPPPPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSREKIVRASDDDDDDAPPRPGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPSPGKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRM
135
536










Molecular Recognition Features






MoRF SequenceStartStop




1) LLFSAV
2) RLLIKKWRKLIS
3) RVSSLKYLDDYS
4) VNKLELLEKYLAEDA
369
78
506
387
374
89
517
401