<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05916

Description Coiled-coil domain-containing protein 47
SequenceMQEVDKNFINSVGGIVQNIKSIQSSISEVLAKLQMADQLDWYKAFIIKHQFNSMLQLLRSDRASHFKNYVFLPIRLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRICNPESLQKQITAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDGEDTALLVAAILKGQNVKPAYSATPASSRGSSGDSGHSKASKAQVRIATTHHPSLILNVKNFNDGRKTCIWMFFLSCLFELVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFTANNVNERETPPVDTASIGAKRSPANAEQKRNDAPNNNFNDDDYGIVEDDESVDDFSHLLDENEFENFPDERRPGKQNAGPSKTVTQLKITDVPGHLRNNWNNFVVELFLIFGLIVYTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDIIEVKIILNPEEMDPFVFALGTKRSAIKNSKEIMDLNLYCSEKKNVEKLGLPSSYILHSEIGEVTTGLIDSKIVSALCKYKDVVDYIHISDQFVGIKPIEMENMTKPPETAKVVMICLNIPGQLRATEEDVSSLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAMLQFLIKAKQIYC
Length734
PositionHead
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.486
Instability index41.31
Isoelectric point6.06
Molecular weight83899.53
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05916
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.47|      15|      91|     321|     335|       1
---------------------------------------------------------------------------
  321-  335 (28.62/18.78)	NNNFNDDDYGIVEDD
  416-  430 (27.85/18.08)	NRPFLEENFSIVGDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.91|      48|      91|      99|     172|       2
---------------------------------------------------------------------------
   99-  165 (73.67/83.16)	VVPDYLRTKPDPQVEQKD..QQISNQVQQRICNPE..SLQKQITAFNRclncildslnasirdsemdGRKT
  187-  238 (71.24/36.46)	VKPAYSATPASSRGSSGDsgHSKASKAQVRIATTHhpSLILNVKNFND...................GRKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.50|      59|     227|     338|     404|       3
---------------------------------------------------------------------------
  338-  404 (92.87/70.28)	VDDFSHLLDenefeNF....PDERrpgKQNAGPSKTVTQLKI.TDVPGHLRNNWNNF.VVELFLIFGLIVYTK
  570-  634 (88.63/50.26)	VVDYIHISD.....QFvgikPIEM...ENMTKPPETAKVVMIcLNIPGQLRATEEDVsSLQPLMIFIFHVLEK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05916 with Med8 domain of Kingdom Metazoa
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