<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05914

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPLAHLLSLVFTLKDNQFVQFCNYFVCWELSEFHDQIKVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIEKDSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILHDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLLGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILQESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELASDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLASSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSSDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTTPAAVDKADSTEFSVDEYSLQNNTNSTTADRSAVIASLRELFSCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKGEIQRRKALQIAFLLKRKKHL
Length962
PositionTail
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.09
Grand average of hydropathy0.154
Instability index45.38
Isoelectric point5.46
Molecular weight109526.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05914
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     860.02|     247|     281|     196|     451|       1
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  196-  438 (349.98/269.66)	.......................................EENRHSFPA..DLLDnmLTFLSFFD......IEKDSYDNLFSANPNEILAKSVRASdSRIpSVVislSGIFAH...VQSMKGIAAMVEALKVAKDIQ.....G.E.SWLNI.....LHDLIMGGILQQHDDSTTLPFSVS........SSY.......LYLRIPRllSQLVAEGIPKETLLGSLRRIATSEAVLNVSDTKARCN..TLQAFLNVL..SELGILQESEKDTLMA.IRDEMR.K..ELYVQEGQ..PTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMM
  439-  721 (322.87/221.59)	SGKSLLYICAAAIsidqlnllaerlikitetykevvpvgEDAQKSVPPshDLFD..MSFLLLHR......LSQ.YYSTTTCLRPGDPFFKTWYFS.SAI.DLV...RNMFDPedlPQLLKNVPL...DLELASDVLsrlrvG.QpGWLNIrtwycIIDLI.PSIVQVVLNEVLLD.TISieelkhifSGL.......LFLNI.........HGVS..CMCSPLLCFAQYVALQKTDEATKLAS..SLFSFFESItpSDAERNRQTDRQTFMV...NSAK.KlfSTY.RELP..VTLMHVLRMNRAPAQLNHSSDDHFPVIGKPENIRSFF
  723-  891 (187.17/124.78)	ASERAGYLTAALI...................................................ariivlVESEQYDSWLSA..........................................FIEALQKVNTMQ.....GmE.KWCNL.......NLACCFI..RPKECTLALIPLL........SNYvlhddrdLFCVAPR..GNILAFFLVKLYLI.ALRYTTTPAAVDKADSTEFSVDeySLQNNTNST..T.......ADRSAVIAsLRELFScK..FEVVRSGElcPTVAFV...............................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.19|      39|     813|      80|     132|       2
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   80-  124 (64.34/73.64)	FLNVVNSYrcyekvGCINEILVLVIYCLDKLNCDFCDADVCVRTS
  140-  178 (71.85/46.38)	YLLTSNNF......PPLAHLLSLVFTLKDNQFVQFCNYFVCWELS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05914 with Med24 domain of Kingdom Metazoa
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