<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05910

Description RNA polymerase II-associated protein 3 (Fragment)
SequenceLKFICNLCHMVLDACQSDFVPVTLTNRLCALIRCDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSQLLNEEISNPSSDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRNSNGVQYLLCAACEIGPLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIVTISKVKPVENDPLLVYPVENPDEKEYQKPLKVVIVRDALKKSQFNSQQLALSDESNVTKQSEQKISDYKPNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSYLLGEFLDGEFVANLLKAFMIKVNSEPQCSISCMERLELIGKAKRFDIVVLFLSRADFIYLKTVLDKAKHVCSKDQAQRWDDLFKKYIETAINKNDNEEEANVESFQ
Length571
PositionMiddle
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.358
Instability index38.36
Isoelectric point5.64
Molecular weight65158.00
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05910
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.99|      25|      31|     279|     303|       1
---------------------------------------------------------------------------
  250-  269 (26.88/16.24)	....YVK.KDYEKAIMCYSRSISAD
  279-  303 (43.97/31.41)	RAMAYLKLKNYAEAYADCSKALTFD
  313-  337 (41.13/28.89)	RGMASKGLNNFDDAVEDFQHVLTLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.31|      24|      32|      27|      52|       2
---------------------------------------------------------------------------
   27-   52 (37.70/27.75)	RLC.ALIRCdkNSNEAPQRIEELIGEL
   60-   84 (39.61/22.92)	RLCfRGVDC..SPEEQVHRVRVLYKEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     216.40|      73|     283|      92|     175|       3
---------------------------------------------------------------------------
   92-  175 (97.07/99.29)	KHLKQISVQ..LVNVQVNDSQLlneEISNPSSDVGPSTEKASSSNNNNGKKLSlSCPKCsciiLRENHGEQVTVeKELPeLSLkAD
  379-  453 (119.33/80.38)	KPLKVVIVRdaLKKSQFNSQQL...ALSDESNVTKQSEQKISDYKPNASIKIT.RIPKC....YAELRADWISI.KEEP.LAL.AD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05910 with Med9 domain of Kingdom Metazoa
Unable to open file!