<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05908

Description "Serine--tRNA ligase, cytoplasmic (Fragment)"
SequenceMSVSLSDFEAKVKNLFKEHAKTGIAHFFFRPYLITSSEECEKKILISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANRIVDFFVRNVTQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFMENISLLDYKDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMYRYYYYYYFAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSKVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQTKHAERTWSQVHVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPARDDHWLLSAEFVGWVSQATDRGPWVPDLNYYAALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSINTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSAPGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGDWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPLCFHFLAPLRWIWILLDDRPYWWVHTAGVSGHLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLSGICWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEAHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNKNNKITSKFFSTKFAQALLGVGLNQLVALIPIGRLPTVLFYELFVPENYIFWYDCHQALIVLLLTMVLDLDNFRVEKGGNVQAVRVSQQKRFQSVDLVDQVVETDQEWRRSRYLSDEWNRLKNLCSKEIGEKIKRKEPVDGNSTLPDSLTDKLQKLTVDQIRALSVSQIKQLRLLIDHEMEKSYKLVENLEAVRFKALSQIGNLVHNSVPVSENEDDNEIVRTWGELEVRKKYSQVDLGIMVDGYDSERGCSVAGSRGYFLKGPLVFLEQALIQLAMHMLFKKKYTPLYTPFFMRKEVMQEVAQLSDFDDQLYKVIGKSSEVKEEIAEEEKYLIATSEQPIAAYHRDEWISKESLPLRYVGFSTCFRQEVGSHGRDTSGIFRVHQFEKVEQFCITSPHDDASWEMLEEMISNAEMFYQTLNIPYRVVSIVSGELNNAAAKKYDLEAWFPGSGAFRELVSCSNCTDYQSRRLRIRYEFVHMLNGTMCATTRTICAILENFQEENGIAVPEALRQYMPDDYKDFIPFVKPAPKVEQAAKRGNKSATAEKSTQYVGTCIILAVDRSTV
Length1750
PositionTail
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.12
Grand average of hydropathy0.000
Instability index40.59
Isoelectric point6.96
Molecular weight201734.24
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
serine-tRNA ligase activity	GO:0004828	IEA:UniProtKB-EC

GO - Biological Process
seryl-tRNA aminoacylation	GO:0006434	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05908
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.68|      40|     387|    1125|    1168|       1
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 1125- 1168 (65.87/53.83)	VHEAHRFFGVDTHRSIelaAKYcHRAEWIHQSTTPL.....ASFFR.DVG
 1511- 1556 (61.81/38.01)	IAEEEKYLIATSEQPI...AAY.HRDEWISKESLPLryvgfSTCFRqEVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     568.14|     137|     387|     224|     365|       2
---------------------------------------------------------------------------
  224-  365 (237.19/175.59)	RLVK..ILHTKL...THYPYRYARNQlMWCLFNFLSGGMQKYSGKSA...W.PS....PALVETYCRMLTYPD..LEI.LGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAfakfQTNASLYW......MYRYYYYYYFAPF
  499-  601 (137.33/89.80)	..................PSDYWHCQ.DW......NDKYQAYQTKHAertW..S....QVHVELSRASLTPNDcpLPVyFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFH..............................PYPVSFLYSTF
  607-  756 (193.61/130.31)	RLVEspAIKQKLalaVHGACVPARDD.HWLLSAEFVGWVSQATDRGP...WvPDlnyyAALVRRLIDTFSEPR..QQ....WSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLV....DKNTVMYWvnaiglIFSALPISYMEPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.50|      26|      30|      49|      77|       3
---------------------------------------------------------------------------
   49-   77 (38.24/37.61)	ANELMEIFTslpQNL.QESAFSI.VISHRVL
   81-  108 (37.25/26.34)	ANRIVDFFV...RNVtQRQMLSIkCICEKLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.01|      23|      34|     953|     986|       4
---------------------------------------------------------------------------
  953-  975 (42.16/42.08)	QRLPIFGETA...QHF.WLAVTKLGDP
 1000- 1026 (34.85/11.98)	HTAGVSGHLShplKQFqWTCETGPGSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.77|      14|      34|    1047|    1060|       5
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 1047- 1060 (26.49/15.19)	DLVLGDLSGICWLL
 1082- 1095 (24.28/13.36)	QVILGIVVGICIAL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     222.85|      71|     796|     849|     930|       6
---------------------------------------------------------------------------
  849-  930 (107.63/122.27)	YQERtkfTMDITTDLYQMLYNVDCEVgdwkyEDLIC...DFFYHVKYMYVGDSVRQ....DTDRIIPMLRPSlqQKLRYISfAQGEQSA
 1651- 1728 (115.21/90.66)	YQSR...RLRIRYEFVHMLNGTMCAT.....TRTICailENFQEENGIAVPEALRQympdDYKDFIPFVKPA..PKVEQAA.KRGNKSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.57|      12|      34|     798|     814|       7
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  798-  814 (17.72/23.12)	LALCHAVwlhsaPGYLQ
  835-  846 (23.85/13.29)	LYVCHLV.....APFLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.78|      13|      26|    1446|    1459|       8
---------------------------------------------------------------------------
 1446- 1459 (17.32/14.93)	LKGPLvFLEQALIQ
 1473- 1485 (24.46/16.16)	LYTPF.FMRKEVMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.29|      26|      26|    1343|    1368|       9
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 1343- 1368 (39.99/28.71)	VDQIRALSVSQIKQLRLLIDHEMEKS
 1372- 1397 (40.30/28.99)	VENLEAVRFKALSQIGNLVHNSVPVS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05908 with Med23 domain of Kingdom Metazoa
Unable to open file!