<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05899

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTSAVHSQIIQREFRDKLIAVKEEMTFYLQEAEQEYYNTALKNSVSVLDLFEIECLRIKMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNIDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSSEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVKLVHSAEADASLPLRVFIKSLFYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSSRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSATAMYLAATAGMRILEIRDPLSSCKIINAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINNSEFTERNYSLKLFGETYNLFVDSYLCCGVNEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRHMLDTSVCSVKKAKIPKPRGEFMAFSGMYWTANFFNCTSGCSYNKFFENTQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYHFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCIVRKMVSSTFLPWSQCSK
Length1035
PositionHead
OrganismTrichinella nelsoni
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.163
Instability index36.79
Isoelectric point5.72
Molecular weight117471.80
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05899
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.03|      19|      22|     234|     255|       1
---------------------------------------------------------------------------
  209-  227 (35.78/19.62)	DENCTEYSALCRMNMAKCK
  234-  252 (31.25/24.48)	DQEAVEYRTAGRLYIRAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     106.44|      22|      26|     705|     727|       2
---------------------------------------------------------------------------
  705-  724 (29.09/16.48)	..NF....LFKNASI.....ISGIDEGI.YGW
  726-  751 (30.51/19.42)	TLNFlshrLMNSASK.....LNDIRPLT.IGA
  962-  983 (16.77/ 6.13)	.........FSDAQIqkiefVNEIDSTE.IGW
  984- 1006 (30.07/13.94)	TLGF....MLNATNQ.....LPEEQPIEhIGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.80|      19|      22|     467|     485|       3
---------------------------------------------------------------------------
  467-  485 (31.20/22.44)	SAEADASLPLRVFIKSLFY
  491-  509 (31.60/22.82)	SLEVDSDFKVRDVINAYAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.90|      23|      26|     802|     826|       4
---------------------------------------------------------------------------
  802-  826 (35.12/30.62)	IIQAQI.VAEDTTNQQPlHPCLPlNY
  830-  853 (38.78/24.05)	VTSEQIfLMPCSLNQKP.NNVLP.NY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.81|      14|     175|     770|     784|       6
---------------------------------------------------------------------------
  770-  784 (22.89/20.80)	FTERnYSLKLFGETY
  947-  960 (26.92/18.55)	FTGL.YSLTLFKDAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.23|      34|      74|      89|     122|       7
---------------------------------------------------------------------------
   89-  122 (56.13/34.00)	LNDFA...YINESITTSAVHSQIIQREFRDKLIA..VKE
  161-  199 (50.10/29.64)	LDEFGtelYVDPWQTFVSIKGKLRKRAFRSPNLAevVKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05899 with Med22 domain of Kingdom Metazoa
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