<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05868

Description Uncharacterized protein
SequenceMDQSQDINLEELFWRSPQHVQMMGGYLHSNNILFYFAESPFFDATSNNASLAIQASYNEAFRHFLETREVFEGRLKTMQGLEFMVTYDPLQDAAQSDTEFAHTPSNIWVIRKQLRQKRPGKEDDVVILSTYYVVGDAVYMAPAVSSVVGNRILSAVTSLTKLLTVASPLPIFTPSYGHVYMPPGPKAVDAPQTTSQLSQQSKEITPVPDSQGSAKTSLTTTSTTTNVKDTSYQDTRNLMEAMNLLSRYGDEFMDETPLSGDPGSFILSKANETTTGGRRMAKTTTNTTTTTILRNLDLTNLQVSPATFHINPYSIASTNQITNMTVTTGQQNKPAVVCVFCGSVGGQNPAHIEAAVALARAFHEQNVHLVYGGGTHGLMGAVAKELVRLSGPEAVHGIIPKALVKFNEDKPQQVQEEKVQEGAGKAHERTVQTDKRTELNETEYGLTTIVPDMHTRKRLMATKVLEGGPGSGFVSLAGGFGTIEEVMEMTTWNQLGIHKVGIVLLNIDGYWDGVLAWIQNAVKEGFISQADGDILVQVQDVKDVLPKLREYTASADRFQLTWGEE
Length565
PositionHead
OrganismTalaromyces islandicus (Penicillium islandicum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Islandici.
Aromaticity0.08
Grand average of hydropathy-0.289
Instability index42.87
Isoelectric point5.40
Molecular weight62037.23
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05868
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.40|      11|      64|     214|     225|       1
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  214-  225 (15.57/11.89)	AKTSlTTTSTTT
  281-  291 (19.82/10.78)	AKTT.TNTTTTT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     215.87|      74|     206|     184|     275|       2
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  184-  275 (105.92/75.43)	GPKAVDA..PQTTSQLS....QQSKEiTPVPDSQGSaktsltttstttNVKDTSYQDTrNLMEAMNLLSRygdeFMDETPLSGDPGSFILSKANETTT
  391-  482 (109.94/61.58)	GPEAVHGiiPKALVKFNedkpQQVQE.EKVQEGAGKahertvqtdkrtELNETEYGLT.TIVPDMHTRKR....LMATKVLEGGPGSGFVSLAGGFGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.34|      23|      46|      34|      56|       3
---------------------------------------------------------------------------
   34-   56 (39.16/27.16)	FYFAESPFFDATSNNASLAIQAS
   83-  105 (41.18/28.93)	FMVTYDPLQDAAQSDTEFAHTPS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05868 with Med6 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PPGPKAVDAPQTTSQLSQQSKEITPVPDSQGSAKTSLTTTSTTTNVKDTSYQDTR
2) SGDPGSFILSKANETTTGGRRMAKTTTNTTT
182
259
236
289

Molecular Recognition Features

MoRF SequenceStartStop
NANANA