<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05844
Description |
Mediator of RNA polymerase II transcription subunit 21 |
Sequence | MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPAIPPPDIPDAAPALAKIPKNSTAPPVPAGAPVPAQSQASPPAQNPAHGAAGAGTSVGDGGQTPGPAAGAGADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQQKRIRELEGELRAVEEERELKMRELKKLRRTLENVLRAVETGIYGDRELLERYS |
Length | 207 |
Position | Middle |
Organism | Aspergillus lentulus |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.494 |
Instability index | 58.40 |
Isoelectric point | 4.97 |
Molecular weight | 22166.63 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP05844
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 61.16| 11| 16| 77| 87| 1
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53- 63 (18.94/ 8.49) KNSTAPPVPAG
77- 87 (21.81/10.89) QNPAHGAAGAG
95- 104 (20.42/ 9.72) QTPG.PAAGAG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 66.80| 16| 16| 145| 160| 2
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126- 139 (20.46/10.17) A.RDLIIKEQQ..IEYL
145- 160 (26.91/15.04) G.IDSSEAEQQKRIREL
162- 178 (19.43/ 9.39) GeLRAVEEERELKMREL
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