<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05785

Description Mediator of RNA polymerase II transcription subunit 11
SequenceMSYKDSGQSPPNLKERLQKLDEIESKVMQIMQSAGGTLGELSRDLPSQKQIEMYARNFRDAVRDVELELISQLNYLSQVLAGLPYEKNAYKETIDLTIAAERLKNSLHADSSQDTLPVGKVTCDLPLKTEAVESDPAVTSTVNESDLSYSDSVSEKTAVPTSAKPHWRFCSVQTVNSPHFFESETPQTSVHEFEIPEFEFDDEIPDLEGDLDDDDFEGPMTPEEFIDEDFERELGWYEKACANFRCSLPCRPWELSIQEVIDSEFRDISRLGIIQVGVTDHDGRSVIAYVTKTLEQYASSEYTLVYFHWGLTSRNKPSFPWLARAYQTFDRSTLLSHIGKLKQLPPVDLFVLFSFKKNLKSLIIVYPTRTVCVLWNLFSAFIRQGFLTGIFVIEMFMIGSVITLCTQFSAKMKKKLHYVKNLHELENYVPLCRLNLPLRIRDYDSKIGLFGVSLSIDPAAVSVIGDHDFNDTPYNDYQQFGVSLEYIKANNGGRKLPIVVEDTITYLRGYGLDTIGLFVKPVHLMALRDAQSMYNRGEYVDLCEINDPHLAAHLLKSFLSELKEPLLTFDLYESILKSCSQSPRQRVISIRRLLTVHLPRDNYDILYYIFKFLTEVSWRFSWQSLMASTILLLPIKVIEHSVKNMVTAVSLSVAMAPCLIRSRQDFVTPSQRVQNLVTSFTQLCITHFESVFIRA
Length695
PositionHead
OrganismTaenia asiatica (Asian tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Taeniidae> Taenia.
Aromaticity0.10
Grand average of hydropathy-0.153
Instability index42.14
Isoelectric point5.32
Molecular weight79397.85
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process
signal transduction	GO:0007165	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05785
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.27|      18|     137|     417|     436|       4
---------------------------------------------------------------------------
  417-  436 (29.07/28.25)	HYVKN.LHELENyvPLCRLNL
  553-  571 (25.20/15.83)	HLLKSfLSELKE..PLLTFDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.51|      11|      27|      91|     101|       6
---------------------------------------------------------------------------
   91-  101 (17.59/10.65)	KETIDLTIAAE
  120-  130 (19.93/13.00)	KVTCDLPLKTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.87|      28|      34|     206|     235|       7
---------------------------------------------------------------------------
  185-  217 (31.85/17.14)	.TPQTSVHE.FE..IPEFefddeipDLEGDLDDDDFE
  220-  254 (45.42/32.37)	MTPEEFIDEDFE..RELGwyekacaNFRCSLPCRPWE
  255-  282 (29.60/12.18)	LSIQEVIDSEFRdiSRLG.......IIQVGVTDHD..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05785 with Med11 domain of Kingdom Metazoa
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