<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05778

Description Uncharacterized protein
SequenceMSKFPSLEGYPLKGRSSGPPDVYPQKPNQLEDALTKQLVEKGFKYHRPVADEHKSGRGGSAPQDLDTAWDLYYNILLLKAQTAPPFEPDNPQIQVESYSGMEKDWGQLKDWLLDLSGANCNRRNAVFHASKGTILSELVSCRFPLSHSLRLINKLIIHATAQLENLKKKQKLDPTMEWTEELLQMLDKLFSGDLSTVSPTKYDCMCAEWDYLFNLLTILYDNDLVEHWDVLKWLASKLDHLYDNSLKLVSQDSSSFCSHHERPQAAKCDPLRSLKFVLPYFQRFCLRFTESELLARRILYRTCSIFSELLRACALRSNPGVVTFTKPEEYIDFFVCSHHRPLLLSTSSIIIALTLHCPSAAVWNKITSETNYTYLSGSPLDLLPCPLSCLPIYPGPEASNLRKCLVETEAVLLERGRLAESGWYLFPSRTITSDECTNETNTEMFVRVLDELDSHDFNQSVETNPIDSLFKKLFHSENLESPRSTTALVTFLCKWAVSPSRTGIHRSIILACLLDYLYSKLPAFNFQACFLAFLDVHAPSSPNVDGPGFRSLVCLFAELIDRGLFNHDAFVRTYIARGVFDSSFHPLANADSVPLSLTSSSVFPPLTAVASLHSSSLNNNFSVQSEISEDNDRNSVDNPDSVRSDLGGGLPQRHSCDLNRHLQYLIHFPLPQDDSYAHEQNQRAQLLYGSSARAHSRAREIPRKVSRDIVKLFTRSAHRLDVVHGELGKRKKNKERIVDVSATPNGTQRCSSGTKETRSLEELLEAISTRFRSLNYYDMEYVISKSMPAYLRSLSGTTSASTTITSCGGESLVADSSGIAASSPSAPNSSRDHIYYPAHNSIFLFMELIETSLNILTLLDTVVETLERLQASSLSAPYPCMSSYLSLVWPRAIGILRAHQAVLITQPSLQQRIFTCLIEHLRRGMQEKLQSKRCIFEYLKSLYFSSAYIKRLCGPSVSPSPFELSQHLPTLNSQTSEILRRLRTYPEDRKTLVDETLKGVLQCRDPDRLAALSGRFVDYSVQCTELALEWLLAVASLVIPLRSGVSISSSVASSGVQNFNSEVVSQLDDPVGWDNLASLIGTLLAHHCIDTEKLFDILINPSLALGLDQSSAPVDSRSEPTVRLACHILHRLFTVEKITQEAQPSFRVSEPSLLFSALRRVNYALFIDTLKMLMIHSNKGKPLELIDEAGEDGSAAGSDDNSSDNGRDSERETDDGPADSSLDPADGFDLIDGPPVSKNKRKRRRVHLASSKNKRRRGVNARRSASGASLLNVRRKNRLASSIHQSTCAFLTNGQPPSDAELREMSLRDFAHLVLREICVTPWVREYFYLISTRLLQENVLIDEMISSNQTRFLLHIIYHPHDVKWVDLAATSDVAEAMLSLISSVNVWSLHATLMELTLLCRQISFTSSKEALDQVANRIVTSFNEQALAYLKPTQMGAFSASTFGEQLPEALPDIEIPETDNSWLLPSLIAKLPQELKMQIVTKTCDILNGIKLFWRHKNDEDQERIVMQHSILLAHPVFSSILHVCMEAVDPLERLYEQLEYFVSGVKETRDRMPENLRTRHILQECLALRLSLLGICLSSMNLTTDRLISGALILAQLIGFGVTEPHSNQTLFFTCLDMLHSLVHNLAAQVGPDNPQYQNLAKKVRKKLAERHFTVGIEYIRPLLFIGRTGYPFVAVTPLDGTAGSGNRGDGGGGAGKLGGSSKFASFKSSGKSGGTNALRYSGGGGGGVGSGSASTTANSGNNNGTPSSGGGGVKTFTRKRGYAFVSRDRFAPWEIYDVNRRSAFLAMCGAVQVPATQSRDEEQANILLSHEHPITHRRSEEFYLQSLFHEAEPLVSSTSTTAVSSPSSSIDSASKQFILGSVPSTKRHSGVDGMPRRMAQQNQRLSKPEDLIYRQQQQQQAPPPLSLPPTQMRMQAPSQQPTKRKRSRAAAQQQEEMLLPPPPPQMYHQSMYPPPQTSSAMAAAQAAESVAAATTTTAPTTVTGKRKRMGGIAGGGGGTAAAVTAAAASVASMRRGAAPPPRSYDNGAVPIPSQQQAWSGGRVSSAAGGSGRVPTQRQNLSEFVQNQTKAQHKAAQQQQIAAAFADGVIPMEEQFSQQQQQDSRFRGGGGGSDPSYGFAEMMPPQSCAGGPFVPDFAAMGSQLRHQRQQRYMEGSGGGGGNQSQQVVPDPPPYPGRPQPTKAPPPQPPPPQMMIQMMSSSTSAPAPSMPTSAVVGEAVTQAQHRAYMMSSAQSSGPAFMGEAPRAAPPPPPPHFSRLYDTTGGGGGEYR
Length2275
PositionKinase
OrganismTaenia asiatica (Asian tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Taeniidae> Taenia.
Aromaticity0.07
Grand average of hydropathy-0.322
Instability index59.46
Isoelectric point7.68
Molecular weight250576.11
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05778
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     195.43|      31|      31|    1911|    1941|       1
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 1915- 1948 (53.90/33.39)	PT.QMRMQA....PSQQPT................KRKRSR.A....AAQQQE......emlLPPP
 1949- 1979 (37.98/20.57)	PP.QMYHQ......SMYPP................PQTSSAmA....AAQAAE........sVAAA
 2026- 2057 (20.74/ 6.67)	PP.RSYDNGavpiPSQQQA...............wSGGRVS.S....AAGGSG.............
 2060- 2085 (28.58/12.99)	PT.QRQNLS....EFVQNQ................TKAQHK.A....AQQQQ..............
 2177- 2194 (28.56/12.98)	PPyPGRPQ.....PTKAPP................PQ...........................PP
 2195- 2254 (25.67/10.65)	PP.QMMIQM....MSSSTSapapsmptsavvgeavTQAQHR.AymmsSAQSSGpafmgeaprAAPP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     123.92|      31|      31|    1686|    1716|       2
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 1686- 1703 (26.17/10.44)	..................GTAGSGNR......GDGGGGAGKL
 1704- 1735 (43.63/22.58)	GGS..SKFASFKSSGksgGTNALRYS......GGGGGGVG..
 1736- 1762 (25.87/10.23)	SGS.............asTTANSGNN..ngtpSSGGGGVKTF
 2135- 2165 (28.26/11.89)	GGPfvPDFAAMGSQL.......RHQRqqrymeGSGGGG....
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.35|      31|      31|     227|     257|       3
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  201-  225 (28.08/13.17)	KYDCMcaEWdyLFNLLTILYDNDL..........V
  227-  257 (58.76/35.87)	HWDVL..KW..LASKLDHLYDNSLKLVSQDSSSFC
  259-  285 (50.51/29.76)	HHE....RP..QAAKCDPL..RSLKFVLPYFQRFC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.21|      38|      38|     618|     655|       5
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  613-  653 (59.39/30.07)	HSsslNNNFSV.QSEI..SEDNDRNSVD..NPDSVRSD.LGGGLPQR
  654-  693 (52.45/25.76)	HS..cDLNRHL.QYLIhfPLPQD.DSYA..HEQNQRAQ.LLYGSSAR
  695-  730 (37.37/16.40)	HS.........rAREI..PRKVSRDIVKlfTRSAHRLDvVHGELGKR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.51|      16|      30|     303|     331|       7
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  288-  310 (18.41/25.50)	FTESEllaRRIlyrtCSIFSELL
  324-  343 (27.11/ 6.11)	FTKPE...EYIdffvCSHHRPLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.84|      12|      29|     344|     358|       9
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  344-  358 (17.67/16.84)	LSTSSIIIaltLHCP
  375-  386 (24.16/13.68)	LSGSPLDL...LPCP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.45|      12|      29|    1109|    1120|      10
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 1109- 1120 (21.40/10.74)	QSSAPVDSRSEP
 1140- 1151 (22.05/11.31)	QEAQPSFRVSEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.39|      15|      32|     758|     786|      11
---------------------------------------------------------------------------
  758-  773 (20.56/43.37)	RSLEELLEAiSTRFRS
  792-  806 (24.83/ 6.38)	RSLSGTTSA.STTITS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.39|      12|      31|    1982|    1993|      13
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 1982- 1993 (20.52/12.33)	TTAPTTVTGKRK
 2010- 2021 (18.87/10.66)	TAAAASVASMRR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.27|      11|     273|    1994|    2004|      14
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 1994- 2004 (23.74/13.29)	RMGGIAGGGGG
 2262- 2272 (23.53/13.09)	RLYDTTGGGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.33|      13|      24|     522|     534|      16
---------------------------------------------------------------------------
  522-  534 (25.33/15.91)	PAFNFQACFLAFL
  547-  559 (22.99/13.66)	PGFRSLVCLFAEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     193.92|      54|      56|     868|     923|      18
---------------------------------------------------------------------------
  822-  866 (49.52/22.82)	.......SSPSAP.NSSRDHIYYP.......AHNSIFLFMELIETslNILTLLdtvVETL
  868-  921 (96.22/61.58)	RLQASSLSAPYPC.MSSYLSLVWPRAIGILRAHQAVLITQPSLQQ..RIFTCL...IEHL
  951-  986 (48.18/24.69)	RLCGPSVS.PSPFeLSQHLPTLNSQTSEILRR....LRTYP...................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.80|      18|      22|    1800|    1820|      21
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 1802- 1819 (32.40/20.46)	TQSRDEEQANILLSHE.HP
 1821- 1839 (29.39/15.00)	THRRSEEFYLQSLFHEaEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.53|      27|      31|     388|     415|      25
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  388-  415 (42.38/31.39)	SCLPIYPGPEASNlRKCLVETEAVLLER
  421-  447 (49.15/32.11)	SGWYLFPSRTITS.DECTNETNTEMFVR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05778 with Med12 domain of Kingdom Metazoa
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