<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05770

Description Uncharacterized protein
SequenceMVDIEYKRELEAKRERVEDIFDFEGCKVGRGTYGSVFKAKRKDAKDDREYALKQIEGTGLSMSSCREIGLLRELKHPNVMTLHRVFLNHTTRKIWLLFDYAEYDLWHIIKFHRTAKVNKTSFNVYPNMVKSLMYQILNGIDYIHSNWVLHRDLKPANIVVMGEGSERGCVKIGDLGFSRLFYQPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTYEPIFHCRQEDIKTSTPYHKEQLERIFRVMGYPADEAWPDMRDMPDYSQLEKDSITRKAYGKYHLEGYLMEKKVNMGRYEISLLQSLLTIDPLRRPSAEDALKHDYFKIGEKPNDDVFGGLPIPYPKREFITDDEPDDNKQQQQQQQQQQGAAAKTGGVPQQQQQQAQPQQQQQHHLHQQKVQQQPTGGVVAGGSGMHTVQHYPSASAQPPMYFASSSALPPMDYLPPLAQPPMYEQGCFFVDTETGAGREPERVFANYPSSALPHPSLPPPSSTPLPSLISNEWRYMGSNHPRAYQCFYPPPPLPLSHANIRGYPGGNMAPPPPQQQQPQQHPNYPRYQ
Length570
PositionKinase
OrganismTaenia asiatica (Asian tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Taeniidae> Taenia.
Aromaticity0.11
Grand average of hydropathy-0.682
Instability index54.36
Isoelectric point7.07
Molecular weight65416.54
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05770
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.30|      29|      30|     495|     523|       2
---------------------------------------------------------------------------
  475-  507 (47.29/19.29)	ETGAGREPERVFANY.PssalPHPSL.......PPPSSTPL
  508-  535 (37.30/13.72)	PSLISNEWRYMGSNH.P.........rayqcfyPPP...PL
  536-  564 (45.71/18.41)	PLSHANIRGYPGGNMaP....PPPQQ.......QQPQQHP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.62|      18|      26|     366|     391|       3
---------------------------------------------------------------------------
  349-  380 (26.18/19.76)	GGLPIpypkrefitddepdDNKQQQQQQQQQQ
  387-  404 (36.45/12.42)	GGVPQ..............QQQQQAQPQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.44|      23|      28|      66|      90|       4
---------------------------------------------------------------------------
   66-   90 (36.54/33.16)	REIGLL.....RELKHpnVMTLHRVF.LNHT
   92-  120 (33.90/22.61)	RKIWLLfdyaeYDLWH..IIKFHRTAkVNKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.91|      14|      30|       6|      19|       5
---------------------------------------------------------------------------
    6-   19 (23.15/20.30)	YKRELEAKRERVED
   33-   46 (23.76/21.05)	YGSVFKAKRKDAKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05770 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ANIRGYPGGNMAPPPPQQQQPQQHPNYPRYQ
2) GREPERVFANYPSSALPHPSLPPPSSTPLPSLISNE
3) VFGGLPIPYPKREFITDDEPDDNKQQQQQQQQQQGAAAKTGGVPQQQQQQAQPQQQQQHHLHQQKVQQQPTGGVVAGGSGMHTVQHYPSASAQPPMYFASSSALPPMDYLPPL
540
479
347
570
514
459










Molecular Recognition Features






MoRF SequenceStartStop




1) HANIRGYPG
2) PQQHPNYP
539
560
547
567