<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05767

Description Uncharacterized protein
SequenceMSKFPSYEDRPLKGKDTGPPDVYPQKPNQLEDALTDQLVKDGFKYNKPVVDEYKSGRKNCLPQDLDSVWDLYYNILVLKAQTAPAFEPENSPAPLKIYSGMDKEWAQLKDWLSDLSGANANRRSTIFDTSKAKILAELTTRRFPLSLALRLINKLIIHTTAPLENLKKKQKLDPTMEWTEELLKMIDKLFTGDLSNISAKFESICGDWDYLFGLLLALYDNDLVEHWDVLKCLASKLEHLYKSCSKSTQQDCPSFCSSKDRSNQAACDPLRSLKFVLPYFQRFCLRFTESELLTRRVLYWSCYVFSEFVNGCKLRATPNCSFDKPEDYTDLFVCAYHRPLLLSISSIIISLTLNCPSAAVWNKITTETNHSYLTGSPLDLLPCSLAFLPIPPGPEAPYFRKCLIETETALLERGRLAESGWCLFPPRALTSNECTDETNAEIFVRVLDELDFQDFSITRETHPIDGLFKKLFLPELLQSPRSLSALVIFLCKWAVSPTRTGLYRSIIVACLLEHLRSNLPGGQLLGFTFQTCLLTFLDQYAPTSPTAEPAAFRALVCLFAELIDRGIFNHDAFVRTYIARGVFDSSLHPLANNDHASVPSTTLHTSNNISNFSIQSEISEDNDRNSVDNPDSVRSDLCGGAGGGLPLRQSPDLNRHLQYLIHFPLPQDESYAHEQNQRAQLLYGSSMRAQLRSRDTLRKLSRDIGKLFTKSAYRLDVVHGELGKRKRNRERSMDLSGTPNNSQRSSFGTTSSAKESRSLEDLIEVIQTRFRSLNYYDMECVISKNMPTYLRVLSGTTSASVSAGGGGGGGLGDVATESFHTDASVAASSPSTFNSGRDPIYYPVHSSIFLFLELIETSLNIICLLDTVADTLERLQASSPAAPYPSMSSYLSLIWLRAIGVLRAHQAVLLTQPDLQQRIFACLIEQLRRGGHERLQSRRCILAYLKDLSYSSAYVKRLWVVWSQTLRSGDSQEAGVQPSPQRAFDSIFNQISLGRPSEIVISLRENSERRKVVVHDTLKEVLQYRDSERLAALFETIVDYSVQCNELALEWLPAMAALIGPNTTTATVISSSPNSPSTNVESGLRLDDPVAWDNLTSLIGTLLAHNCLDAVLLFEKLINPSLAHGLDQSSVPVDSRLEPTVRVACHILHRLFTAETVCQPSGQQEGQQSQSLPTFRVSEPLLLTGALQKVADSRGAYIYLIDSMKMLMIHSNKGIPLEFADEGGEDGSAAGSDDNSTDNDRDSDRDTDDGHADSSLDLYDGFDLTDGPPTSKNKRKRRRVHLASSKNKKRRGVNAKRNSAGSNLFNSRRRNWLPGRIHRSTCNFLTTGQPPSDSEVRAMPLRDFAHLVLREICVTPWVRENFYRIPGLLLANNVLIDNMISGNQTRFLLHIIYHPHDVKWVDLAANPENVAEVMLSLISGVNIWTLHSTRMELNLLCMHISPTSSKEALDQVANRIVTGFNEQALSYLRTASGGAFNDASSTYLLPEGLPEIEIPESDNSWYLPSLIAKLPHELKMQIVTKTCDILYGIKQFWRHKNDEDQERIVMEHSILLAHPVFSSILHVCMETVDPLERLYEQLECFVSGVKETRDRMPENLRTRHILQECLALRLSLLGICLSSVNLATDRLTSGALILAQLIGFGVTEPHSNQTLFFTCLDMLHTLVHNLASQAGPDSQQCQNLAKKVRKKLAERHFTVGIEYIRPLLFIGRTGFPFVAVAPLNGTAGSGNRNDGGGGGAGKLGGSSKFASGGSFKANSKSGGSNASRYGGGNTGNSGAGNLTSGGGVKSFSRKRGYAFISRDRFAPWDIYDVNRRPTFLAMCSAVEVPATQSRIEEQANLLLSHEHPLSFRRSEEFYLQSLFNDAEASVSSASTAAAVASPSPSSSGDLTAKQFVLGPVPPMKRQPGVESLPRRAPPQQAPRLPKPPTAADDLMYRQQQAQIRLQTPPSTQTQQPKRKRSRAAPQEEMLLAPPPPPPPPPQLYHQGLYGASQNSAMAAAQAVESAAAASTVTGKRKRLGGGMAGGAGIRRAVPQLNYDNGGMSAAVLSHQHQQPWPPRMAGPPPAGMPGRVPNQRQNLSDFVQNRNKAQQQQQKAAQQQQQQQQQQMAAAFAAGVVSMEERFPQQDPRRAGNDPLQARLTFSVGEVFALDCPLQSLDPLGLMANARVWFMSSGRGQGDPNYPFPEMMPSQSGGPFPDFQLESQLRHQRQQQQRYVGGQQQVVPDPPPYPGRVQHQAKATPMMQMLSSAPSSAAMSGQHLPSRSTPANVTSYMIPQTHRTPFPGGEHPRPPAPPPPNTISSSSSFSRLYDTGDYR
Length2311
PositionKinase
OrganismMesocestoides corti
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Mesocestoididae> Mesocestoides.
Aromaticity0.08
Grand average of hydropathy-0.364
Instability index60.57
Isoelectric point8.03
Molecular weight255881.12
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05767
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     254.54|      32|      50|    2046|    2077|       1
---------------------------------------------------------------------------
 1895- 1929 (24.90/ 6.95)	.....P.........V...P....PmkRQPG..veslPrraPPQQ...AP.RLPKP..PTA.ADD
 1968- 1986 (29.22/ 9.62)	....AP.........P...P....P............P...PP......PPQL..Y..HQG.LYG
 2046- 2077 (68.82/34.00)	HQHQQP.........W...P....P..RMAG......P...PPAG...MPGRVPNQ..RQN.LSD
 2094- 2130 (35.90/13.73)	QQQQQQ.........Q...Q....Q..QMAA......A...FAAGvvsMEERFPQQdpRRA.GND
 2150- 2194 (31.18/10.82)	LQSLDPlglmanarvWfmsS....G..RGQG......D...PNYP...FPEMMPSQ..SGGpFPD
 2203- 2237 (40.72/16.69)	HQRQQQ..................Q..RYVGgqqqvvP...DPPP...YPGRVQHQ..AKA..TP
 2272- 2293 (23.81/ 6.28)	QTHRTP.........F...PggehP..RPPA......P...PP..........PN..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      89.15|      13|      14|    1721|    1733|       2
---------------------------------------------------------------------------
  795-  806 (19.89/ 8.70)	GTTSASVS.AGGG
 1721- 1733 (25.13/13.24)	GTAGSGNRNDGGG
 1737- 1749 (20.10/ 8.88)	GKLGGSSKFASGG
 1771- 1783 (24.02/12.28)	GNSGAGNLTSGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.61|      70|     164|    1325|    1440|       3
---------------------------------------------------------------------------
 1322- 1399 (106.69/128.50)	C.NFLTTGQPPSDSEVRAMPLRDFAHLVLREICVTPwvRENF......YRIP.GLllaNNVLIDNmiSGNqTRFLLHIIYH.PHDVK
 1437- 1515 (101.92/50.47)	CmHISPTSSKEALDQVANRIVTGFNEQALSYLRTAS..GGAFndasstYLLPeGL...PEIEIPE..SDN.SWYLPSLIAKlPHELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.20|      18|      33|     149|     169|       5
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  149-  169 (24.48/22.61)	LRLINKLIihtTAPLENLKKK
  183-  200 (30.73/18.58)	LKMIDKLF...TGDLSNISAK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.99|      34|     117|     278|     312|       6
---------------------------------------------------------------------------
  278-  312 (63.24/43.98)	PYFQRfCLRFTESELLTRRVLY...WSCYVFSEFV.NGC
  397-  434 (56.75/34.21)	PYFRK.CLIETETALLERGRLAesgWCLFPPRALTsNEC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.41|      17|      38|     466|     482|       7
---------------------------------------------------------------------------
  466-  482 (28.64/14.55)	GLFKKLFLPELLQSPRS
  501-  517 (30.03/15.62)	GLYRSIIVACLLEHLRS
  915-  929 (20.73/ 8.53)	.LQQRIF.ACLIEQLRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.55|      36|      38|    1104|    1139|       8
---------------------------------------------------------------------------
 1104- 1139 (61.25/35.43)	AHNCLDAVLLFEKLINPS.LAHGLDQSSVPVDSRLEP
 1144- 1180 (60.30/34.75)	ACHILHRLFTAETVCQPSgQQEGQQSQSLPTFRVSEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.84|      27|      38|    1560|    1592|       9
---------------------------------------------------------------------------
 1560- 1592 (38.98/49.18)	ILHVCMETvdpleRLYEqLECFVSGVKETRDRM
 1601- 1627 (44.86/34.02)	ILQECLAL.....RLSL.LGICLSSVNLATDRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.65|      12|      41|     839|     855|      10
---------------------------------------------------------------------------
  839-  855 (14.82/25.08)	PiyYPVHSSiflFLELI
  883-  894 (24.84/15.49)	P..YPSMSS...YLSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.75|      33|     164|    1042|    1091|      12
---------------------------------------------------------------------------
   12-   49 (50.93/21.62)	LKGKDTGPPDVYPQKPNqleDALTDqlVKDGFKYNKPV
 1058- 1090 (56.82/27.50)	LIGPNTTTATVISSSPN...SPSTN..VESGLRLDDPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.62|      26|      32|    1220|    1251|      13
---------------------------------------------------------------------------
 1220- 1245 (44.34/30.49)	ADEGGE..DGSAAGSDDNSTDNDRDSDR
 1252- 1279 (40.28/15.17)	ADSSLDlyDGFDLTDGPPTSKNKRKRRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     152.13|      41|      51|     615|     655|      14
---------------------------------------------------------------------------
  584-  605 (25.72/ 9.87)	................DSSLHPLANNDHASVP....STTLHT
  615-  655 (70.44/41.50)	QSEISEDNDRNSVDNPDSVRSDLCGGAGGGLPLRQ.SPDLNR
  669-  706 (55.97/31.27)	ESYAHEQNQRAQLLYGSSMRAQLRSRD....TLRKlSRDIGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.01|      13|      47|     486|     498|      15
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  486-  498 (26.04/17.29)	LVIFLCKWA.VSPT
  533-  546 (19.98/11.27)	LLTFLDQYApTSPT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05767 with Med12 domain of Kingdom Metazoa
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