<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05753

Description Uncharacterized protein
SequenceMVDIGFKRELDVKRERVEDIFDFEGCKVGRGTYGSVFKAKRKDNSDDREYALKQIEGTGLSMSSCREIGLLRELKHRNVMTLHRIFLNHTSRKIWLLFDYAEYDLWHIIKFHRTAKGNKTYFNVSQNMVKSLMYQILNGIHYIHSCWVLHRDLKPANIVVMGEGPERGCVKIGDLGFSRIFYSPLKPLADLDPVVVTFWYRAPELLLGARHYNKAIDIWAIGCIFAELLTFEPIFHCRQEDIKTSTPYHKEQLERIFRVMGYPSDETWLEMRTMPDFPQLSRDSITRKTYGKYYLEGYLMEKKVNMNPNEVSLLKSLLTMDPTKRPSAEEALEHDYFKTGDKPNDDVFGGLPIPYPKREFITDDDQDDNKQQQGMAKAGVVAQQQPPQQVSQQQAKVPQQQGPPPPNQQHTVPHYPAQVQSTMYYAPQPGLGQPTVRQVDEPVPFFLIRS
Length450
PositionKinase
OrganismHymenolepis nana (Dwarf tapeworm) (Rodentolepis nana)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Hymenolepididae> Rodentolepis.
Aromaticity0.11
Grand average of hydropathy-0.567
Instability index52.03
Isoelectric point8.06
Molecular weight52140.09
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05753
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.05|      16|      16|     372|     387|       1
---------------------------------------------------------------------------
  372-  387 (30.14/19.52)	QQ.GMAKAGVVAQQQPP
  388-  404 (26.91/16.68)	QQvSQQQAKVPQQQGPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.63|      27|      41|     227|     254|       2
---------------------------------------------------------------------------
  227-  254 (45.64/32.40)	ELLTFePIFHCRQEDIKTSTPYHKEQLE
  270-  296 (50.00/31.14)	EMRTM.PDFPQLSRDSITRKTYGKYYLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.46|      15|      37|     152|     166|       4
---------------------------------------------------------------------------
  152-  166 (26.80/14.41)	DLKPANIVVMGEGPE
  190-  204 (28.66/15.81)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05753 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PTKRPSAEEALEHDYFKTGDKPNDDVFGGLPIPYPKREFITDDDQDDNKQQQGMAKAGVVAQQQPPQQVSQQQAKVPQQQGPPPPNQQHTVPHYPAQVQSTMYYAPQPGLGQPTVRQVDEPVP
322
444

Molecular Recognition Features

MoRF SequenceStartStop
1) AQVQSTMYYAPQ
2) FFLIRS
417
445
428
450