<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05691

Description Uncharacterized protein
SequenceMQQSPLRIKHRDLRDFGCGSVGRVIHFLHAKQEEDNLGADRLKKGYQVAVTSYEHESIVYNVKMPRLDRLDDTMLRGAQLVMQIMAKKMELNANLDKERKRAGSAIAKDGIGSGGNGVGGGTQIHFQQFSHNAEKAKKSKERNDWFTDLAHGKSLAVLARKPPFFRKKEDALEYLCDYKVPVNRALWFLKLIAIGGQGCSSNVNKQKKSTTDQLTSELASLFTKYVKLMLNQMSDSAKLESNIVYTDRWPHFVYICKHAYEDGMVEKQEFLMDLLDIFNDRFVQPIENRQNDKSSIHSFLHHGPGLASSSNQSHYITLFRLFLLFICQYTDQITQNIVLSKRCAFLVCHRLELYRDEAEEREGRSVDCVELFDDMQQCIHQRAIILTLCGMLYAILIDCPAALVWNKYEVSPGRPPTMLHQMCGSPLDHLPCPFESLPLPPGHGTERLQEFIQLRLAEVRRRSRACENKWSLNYAQKKGFATMVLQCLEIVGVLDAARLDQPNCIEKIYAIIFNGPSKESFEHEHAIRVKMLLQWAVTMEREGTYRAILVAQLLAFRINHRKTFKFGSLTLQEILLEFLVTEGPDPETADKDRFCQEFANLVLLFIELQRAGVFSHDFYVKELIRTGEMLEYIPLMQKIRKRKESKQKQASNMLSSTFVSQSSEATAALLAGAVTTPSPLVTMPTDLPDEHPYLWEDLSIHERLLIHLPIPQSAEYRSECNQRQALIC
Length728
PositionKinase
OrganismElaeophora elaphi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Elaeophora.
Aromaticity0.09
Grand average of hydropathy-0.305
Instability index45.04
Isoelectric point7.99
Molecular weight83324.16
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05691
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.42|      52|     178|     445|     502|       1
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  445-  502 (73.69/88.95)	TERLQEFIQLrLAEVRRRsRACENKWSLNYAQkkgfATMVLQCLEIVGVLDAARLDQP
  626-  677 (84.73/74.51)	TGEMLEYIPL.MQKIRKR.KESKQKQASNMLS....STFVSQSSEATAALLAGAVTTP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.79|      39|     178|     360|     400|       2
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  360-  400 (67.44/50.20)	EREG..RSVDCVELFddMQQCIHQRAI...ILTLCGMLYAILI.DCP
  540-  584 (49.35/29.99)	EREGtyRAILVAQLL..AFRINHRKTFkfgSLTLQEILLEFLVtEGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.18|      28|     182|      58|      85|       3
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   58-   85 (48.29/32.20)	IVYNVKMPRL.....DRLDDTMLRGAQLVMQIM
  243-  275 (45.89/30.26)	IVYTDRWPHFvyickHAYEDGMVEKQEFLMDLL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     185.50|      54|     150|     123|     178|       5
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  123-  178 (89.80/67.93)	QIHFQQFSHNAEKAKKSKERNDWFtdLAHGKSLAVLARKPPFFRKKEDALEYLCDY
  276-  329 (95.70/65.93)	DIFNDRFVQPIENRQNDKSSIHSF..LHHGPGLASSSNQSHYITLFRLFLLFICQY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05691 with Med12 domain of Kingdom Metazoa
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