<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05689

Description Uncharacterized protein
SequenceMLVRSGQKFCGEHVIWDELNEERVVCPNDPKHTINRSQLQKHLSSQCNGRLSDEPWLVENFNLTGSPKEVEPWYRPTNDELLKMRKIVERIYDQIANDIEDSFLKNDYVEGCAADLPKINKKHIRQISSIIEHLRVANLLNNNERWCLVDFGTGRAELFYWMAKIAPKCRFLLVEKMGSRNKFDNKIHKELDGAFFERLRCSVEHLDLSKTDLIRNADNTAAVCKHFCGVATDFGIRCLMNGVKSGLNICGFVLAPCCHHRTTYREYVGCRFLESHGICSAKEFASLRHISTWAVCGFPSQENFNGDISVLPRSMQSENLDQQKTILESISLNSAEKELLGQKAKAVLEFGRVVELQKFGYDVSLCRYVERTVTPENLLIVGRKKQNFERVSNLDLLRGSGLNSVSGPETSEEQKKRFEIECEFVQALANPHYLNFLAQRGYFKEPYFINYLKYLLYWKRPEYARALKYPQCLHFLEAVQSSAFREAITCTANAKFIEEQQLLQWQYYTRKRQRLHISAAERELKFVEALEGTCERMLQYKLHKEKSDISRFAKEESSTMKALNELRNKGVKMLYIYEIAVASGLLHMTTSIYVVSRGGFGYRSETHKTEVELGMPYEMWDTPSVEVVTLKQNCETLLERYENDLEQWYHIQDRPLLEEYLCEKRVLKRVERDCMKTSNNLEL
Length683
PositionMiddle
OrganismElaeophora elaphi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Elaeophora.
Aromaticity0.10
Grand average of hydropathy-0.469
Instability index44.39
Isoelectric point7.71
Molecular weight79463.12
Publications









Function






Annotated function

tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro)
and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).



GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-UniRule
transcription coregulator activity	GO:0003712	IEA:InterPro
tRNA 2'-O-methyltransferase activity	GO:0106050	IEA:UniProtKB-UniRule

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05689
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.62|      15|      20|     265|     279|       2
---------------------------------------------------------------------------
  265-  279 (28.58/16.44)	REYVGCRFLESHGIC
  282-  296 (27.04/15.19)	KEFASLRHISTWAVC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.50|      15|      20|     314|     328|       3
---------------------------------------------------------------------------
  314-  328 (25.13/17.90)	SMQSENLDQQ.KTILE
  334-  349 (18.37/11.06)	SAEKELLGQKaKAVLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.23|      19|      20|     211|     229|       4
---------------------------------------------------------------------------
  211-  229 (35.61/20.55)	TDL.IRNADNTAAVCKHFCG
  232-  251 (31.62/17.55)	TDFgIRCLMNGVKSGLNICG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.74|      27|     141|     499|     528|       5
---------------------------------------------------------------------------
  455-  486 (38.88/16.92)	LLYWKRpeYARAlkyPQCLHFLEAVQSSAFRE
  502-  528 (47.87/30.00)	LLQWQY..YTRK...RQRLHISAAERELKFVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.53|      14|      21|      70|      83|       7
---------------------------------------------------------------------------
   70-   83 (27.48/16.49)	VEPWY....RPTNDELLK
   88-  105 (19.05/ 9.47)	VERIYdqiaNDIEDSFLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05689 with Med31 domain of Kingdom Metazoa
Unable to open file!