<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05666

Description Uncharacterized protein
SequenceMDGLDIESCSSSHSSSSLRGLNLICSTNHIDRRPSDSSNSSETSISPAPSNINSNRRRTSIHESIRDDMFWEKRRHNNDITKKSRERRRMNDMIMEQKLLELTKENNLLRSRLKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQQTLRLVTSAAHDTVIVSTAQRKNNIDVMIPTVPSLPVSSVTTLAANLANVIGPPSKLPAMFPTHLFTATPLLTTSSGSVPSPIFPSSATAPTSLLTPAGASATSQVSASAAQQLPALQICTLQAALQQVQQNYCSSSGPTTISSGHGAFQPFHSSRDPTSSTQSYSPDSSTADIAPLDYSMHGTTHKETSSDSSSHILRYELLERQPDLSTETETEQQISNDTLAQSSSSSDKARESDTDDKPRSLLGSLLSTKRTSPLVAQSRTDTHSGLNNSSPKDNDLKNCLSSLAVNLSNALTVPGTRTVISDVSSKPDTVYSGKTIKSDSSDSMESPTSNNSTTDSMRSQLSPAPKHSAIVKALRSRPSSKQQYIDRRRRNNEAAKRCRANRRAQFEYRSKRAQQLEAENDELRREMNRLNQELEQLKALHAAKNANIL
Length590
PositionKinase
OrganismBrugia timori
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.03
Grand average of hydropathy-0.918
Instability index83.46
Isoelectric point9.20
Molecular weight65258.13
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05666
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.83|      15|      15|     115|     129|       1
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  115-  129 (34.42/13.54)	QQQQQQQQQQQQQQQ
  131-  145 (34.42/13.54)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.54|      21|      21|     214|     234|       2
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  184-  202 (17.65/ 6.50)	...MIPT..VPSLPVssVTTLAAN
  214-  234 (38.40/22.00)	PA.MFPTHLFTATPL..LTTSSGS
  236-  257 (30.49/16.09)	PSpIFPSSATAPTSL..LTPAGAS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.52|      21|      22|     291|     311|       3
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  291-  311 (38.64/21.97)	SSSGPTTISSGHGAFQPFHSS
  316-  336 (35.88/19.82)	SSTQSYSPDSSTADIAPLDYS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.08|      21|      21|     514|     534|       5
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   81-   92 (17.84/ 7.45)	TKKSR........ERRRM.......ND.
  514-  534 (37.31/23.83)	ALRSRPSSKQQYIDRRRR.......NNE
  536-  563 (29.92/17.61)	AKRCRANRRAQFEYRSKRaqqleaeNDE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.26|      15|      15|     449|     463|       6
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  449-  463 (25.20/14.60)	SNALTVPGTRTVISD
  466-  480 (26.06/15.32)	SKPDTVYSGKTIKSD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.01|      10|      15|       3|      13|       7
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    3-   13 (15.14/14.48)	GLDIeSCSSSH
   20-   29 (19.87/13.13)	GLNL.ICSTNH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05666 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GLNLICSTNHIDRRPSDSSNSSETSISPAPSNINSNRRRTSIHESIRDDMFWEKRRHNNDITKKSRERRRMNDMIMEQKLLELTKENNLLRSRLKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQQTLRLVT
2) LTVPGTRTVISDVSSKPDTVYSGKTIKSDSSDSMESPTSNNSTTDSMRSQLSPAPKHSAIVKALRSRPSSKQQYIDRRRRNNEAAKRCRANRRAQFEYRSKRAQQLEAENDELRREMNRLNQELEQLKALHAAKNANIL
3) SGHGAFQPFHSSRDPTSSTQSYSPDSSTADIAPLDYSMHGTTHKETSSDSSSHILRYELLERQPDLSTETETEQQISNDTLAQSSSSSDKARESDTDDKPRSLLGSLLSTKRTSPLVAQSRTDTHSGLNNSSPKDNDLKNCLS
20
452
300
163
590
442










Molecular Recognition Features






MoRF SequenceStartStop




1) AIVKALR
2) KQQYIDRRRR
3) RYELLER
510
522
355
516
531
361