<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05640
Description |
Uncharacterized protein |
Sequence | MDDEGHNKPVLPIVPEKCGPPTISLNYLLDFAIQQIYHEITVLSELLPKKLDGDKKISLVQFAHSTRMLFVKLLAVVKWVKSSKKFESCAAICYLLDQHSQYFVETADRLVAISREELVLARLPAFQITAAVDVLQYRISKVSSTLSPRIKGIVIRNGMLILTVPGEFEVSLTVLGEREQTPWTLLNIKMLVEDYEIGYGAQLVHPLQLHMLHSVLQHRMDIAKNPINEVYNFLHTFAQSLQLDVLFCQASQLAMGRLRNKIVIENYDPKERVLSIGYWVQRITKKGLTNHVRLEPQYRVTIFGDDGCDTTLNVRHHPVAPDLGQLDSRSGCENRTFTATDITSAYIMRLSIDRLLSETLVVRCRERLLRIRKRLKAAKPLSIVIYAEFLPGSAAELKEFETVLYNGQSIDSLRKRIDRLKVLLMIERYRRSVATLQVRIINENQMAPFFKKVHSLPADRICLQFIKEEHFYLEKQLISAPIDEVVDKEAKAFGRFENDDVWTPNVKFNRLGPSMVRQLTTAVAAVDDRISFMRVCEELDKKRIGYRSVEEEPHVGGLILHITDVSAVVDVRCAAFLRNMARCCLRLDSRTRVVWPLECCMVNIPLVRDLSPYRKGRKIGVWVHEQTGINAGGPTDTIATSIIERLTRYSHIYDTVNRFAKAYDAHYNKLCSVCLIPCLSQDSFTIKAQKSKFLVQAYTFHKLVIAYGRERDQQLIVSFRPRSALNERFNLNFGQVGNKNVTLPISVYDSPEVNLQEATRWNAHCMMTTILKEKYDGLSIDE |
Length | 782 |
Position | Tail |
Organism | Angiostrongylus costaricensis (Nematode worm) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida>
Metastrongyloidea> Angiostrongylidae> Angiostrongylus.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.114 |
Instability index | 38.05 |
Isoelectric point | 8.98 |
Molecular weight | 89526.03 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU365082
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:UniProtKB-UniRule
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP05640
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 120.62| 40| 66| 433| 478| 1
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433- 478 (58.72/51.20) VATLQVRIineNQMAP.FFKKVHSLPA...DRICLQFIKEEhfyLEKQLI
501- 544 (61.91/37.15) VWTPNVKF...NRLGPsMVRQLTTAVAavdDRISFMRVCEE...LDKKRI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 195.63| 59| 342| 233| 292| 2
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233- 292 (97.31/66.54) FLHTFAQ.SLQLDVLFCQASQLAMGrLRNKIVIENYDPKERVLSIGYWVQR...ITKKGLTNHV
576- 638 (98.32/62.80) FLRNMARcCLRLDSRTRVVWPLECC.MVNIPLVRDLSPYRKGRKIGVWVHEqtgINAGGPTDTI
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