<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05636

Description Uncharacterized protein
SequenceMLTLSGPAASAGAAPVQAAAPATFQQQQPGAAPPSSCLATSGASSSDGGASNITSGTSSEYMVKPSSQEGLKLTINKTGSSKSSSSGASSSSIGMGKTKGPSSGSSGGASASASSSSYAKKQHTGLKPGVNSGPASKKATASTGGATTSGGASSSSSKHLFQKANSSGNLSSKLSGSASGGGVLLTKSNSTNSFQEHNAPRRRPSMGGLASSGGGAGGAPRKGGSSAGGGSSSGAVSPAALTGSMSQPPPRFDHHTDMMTILQYASPTMAASMEGFIKGLHNKFQIPKLSQRGSGGSGRSTPSSTEQTSTTATSTVVSATTSSALPDPDTKPSAAPPPPGNDLLLNLSTTAPMPSGDGIDEELLASLAGE
Length370
PositionMiddle
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.02
Grand average of hydropathy-0.428
Instability index60.27
Isoelectric point9.82
Molecular weight35658.61
Publications
PubMed=15632085
PubMed=17994087
PubMed=23185243

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05636
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     124.15|      33|      35|     100|     133|       1
---------------------------------------------------------------------------
   27-   64 (43.93/11.12)	QQPGAAPP.SSClatsGASS.SDGGASniTSGTSSEYMVK
   93-  121 (36.90/ 8.01)	..IGM......G.ktkGPSSGSSGGAS..ASASSSSYAKK
  122-  158 (43.31/13.25)	QHTGLKPGvNSG.pasKKATASTGGAT..TSGGASSSSSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.92|      13|      15|     207|     219|       2
---------------------------------------------------------------------------
  207-  219 (24.37/ 6.42)	GGLASSGGGAGGA
  223-  235 (25.54/ 7.14)	GGSSAGGGSSSGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.96|      13|      17|     335|     347|       4
---------------------------------------------------------------------------
  335-  347 (26.15/12.42)	APPPPGN....DLLLNL
  351-  367 (18.80/ 7.07)	APMPSGDgideELLASL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.14|      14|      17|     301|     314|       5
---------------------------------------------------------------------------
  301-  314 (23.25/ 9.47)	TPSSTEQTSTTATS
  320-  333 (24.89/10.62)	TTSSALPDPDTKPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.72|      20|     167|       4|      26|       7
---------------------------------------------------------------------------
    4-   23 (30.89/10.80)	LSGPAASAGAAPVQAAAPAT
  174-  193 (32.83/15.64)	LSGSASGGGVLLTKSNSTNS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05636 with Med1 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LHNKFQIPKLSQRGSGGSGRSTPSSTEQTSTTATSTVVSATTSSALPDPDTKPSAAPPPPGNDLLLNLSTTAPMPSGDGIDEELLASLAGE
2) MLTLSGPAASAGAAPVQAAAPATFQQQQPGAAPPSSCLATSGASSSDGGASNITSGTSSEYMVKPSSQEGLKLTINKTGSSKSSSSGASSSSIGMGKTKGPSSGSSGGASASASSSSYAKKQHTGLKPGVNSGPASKKATASTGGATTSGGASSSSSKHLFQKANSSGNLSSKLSGSASGGGVLLTKSNSTNSFQEHNAPRRRPSMGGLASSGGGAGGAPRKGGSSAGGGSSSGAVSPAALTGSMSQPPPRFDHHTDMMTILQYA
280
1
370
265

Molecular Recognition Features

MoRF SequenceStartStop
1) DHHTDMMTILQ
2) DLLLNLSTTA
3) GAAPVQAAAPATFQQQQ
4) GIDEELLASLAGE
5) GLKLTINKT
6) IGMGKTK
7) SKHLFQKAN
8) SSYAKKQHTGLKPGV
253
342
12
358
70
93
157
116
263
351
28
370
78
99
165
130