<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05550

Description Uncharacterized protein
SequenceMPFIDDALLWCPDNDGRLVGGLDLANCMTDDSSVNAENINATIGSSNNNSSQQQQLQQQLQQQQQSSELCGTAARNVNVVVEPLCGSDSSDELFRTLSESNFEIESLLSDLATVEVKVENEENNNNVISDNDFASVAAAVVAGDDLLAKDNVQLSVQGLVDTVSASLADSGGGGGGGHGQALLGFGASSATATTTAAAAAKRNGFLLPCDLLNNNNNSNSNANGNGDCTPEESRFVTATSASANPLLVEKLMSKCLNIDKRMDKLDDTEIPIVKQSTSPSPHQQQQQQQQQQQHQQQQQHLQQSQQSSNNGHQQQQQQQQQQQQQQPLAIPHRPLLHNLLSGGSIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPTTAATSAAAAATHSAAAAAAAAAAAAAHLHTGTFLHPNLYQNNTANSLRNIWNRSVGVPDNYYGNSGNSGSGGVNPGTPGTPSYLTTSYFNAPTVASTQRSVAANGFGTHQHHSLQHQQQPQQQQQQQQQQLSHHQQQLHHQQQQQQQQQQQQQQQQQQQQQHPQSQHPHQLHSHSTIANAAAAAAAAAAVVSSSSAVAAAAMLNAGSAQNGVIQQPATSSVNYDLSYMLELGSFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIVEIDCNGV
Length752
PositionKinase
OrganismDrosophila mojavensis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.693
Instability index58.53
Isoelectric point6.20
Molecular weight81251.12
Publications
PubMed=17994087

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro
sequence-specific DNA binding	GO:0043565	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05550
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     228.54|      27|      29|     275|     301|       1
---------------------------------------------------------------------------
   45-   65 (29.79/ 6.30)	....SSNNNSSQQQQLQQQLQQQQQ..
  275-  301 (59.06/18.60)	QSTSPSPHQQQQQQQQQQQHQQQQQHL
  302-  328 (54.23/16.57)	QQSQQSSNNGHQQQQQQQQQQQQQQPL
  504-  530 (55.01/16.90)	HQHHSLQHQQQPQQQQQQQQQQLSHHQ
  531-  546 (30.45/ 6.57)	QQLH...HQQQQQQQQQQQ........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.45|      15|     165|     407|     421|       2
---------------------------------------------------------------------------
  407-  421 (27.27/14.10)	HSAAAAAAAAAAAAA
  569-  583 (27.18/14.03)	HSTIANAAAAAAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.88|      29|      36|     615|     646|       3
---------------------------------------------------------------------------
  615-  646 (42.23/34.75)	SVNYDLSYMLELgsFQQRKaKKPRKPKL...EMGV
  654-  685 (48.65/28.62)	STTYLWEFLLKL..LQDRE.YCPRFIKWtnrEKGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.25|      40|     241|     198|     245|       4
---------------------------------------------------------------------------
  204-  245 (67.22/57.90)	G.FLLPcDLLNNNN.NS.................NSNANGNGDC...TPEESRFVTaTSASANP
  426-  487 (54.03/26.64)	GtFLHP.NLYQNNTaNSlrniwnrsvgvpdnyygNSGNSGSGGVnpgTPGTPSYLT.TSYFNAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     160.24|      40|     210|     158|     200|       5
---------------------------------------------------------------------------
  158-  200 (62.01/43.31)	GLVDTVSASladSGGGGGGGHGQALLGFGASSATATTTAAAAA
  342-  368 (35.96/16.71)	................GGSIHNPHHRNYTTATTGSFPPSPADS
  369-  405 (62.27/36.23)	GVSDVDSSS...SGGQPCADELKARLGM...PTTAATSAAAAA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05550 with Med12 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DLLNNNNNSNSNANGNGDCTPEESRFVTATSASA
2) NIDKRMDKLDDTEIPIVKQSTSPSPHQQQQQQQQQQQHQQQQQHLQQSQQSSNNGHQQQQQQQQQQQQQQPLAIPHRPLLHNLLSGGSIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPTTAATSAAAAATHSA
3) NNTANSLRNIWNRSVGVPDNYYGNSGNSGSGGVNPGTPGTPSYLTTSYFNA
4) VASTQRSVAANGFGTHQHHSLQHQQQPQQQQQQQQQQLSHHQQQLHHQQQQQQQQQQQQQQQQQQQQQHPQSQHPHQLHSHSTIANAAAAA
210
257
436
489
243
409
486
579

Molecular Recognition Features

MoRF SequenceStartStop
NANANA