<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05544

Description "Uncharacterized protein, isoform E"
SequenceMNQNQIQQLTSHLSQALDQNYDVVNMEAVLSVICALEGTTITKEQLEATRLAKYINQLRRRTKNDQLARRAKSLLKKWREMVGIHQQTTIEPQPQPLAHLSFKPIVGTHFPETESNTVEVMVNSTQYTSQSSPPSSQRVNTDLHPNVDSSEPHHINFSSLINNNINTDNRDDSLAIISKSIKHPRTIESKSQKSATFINEHSSNSVSSVMVANEKLNETSIVIDIVSDSDENDSQSQPVNNHQKLATVSSSLALPAVYPRPKKIKKDKKRKEKDGRDKPSQFYFNDGVPQQLTNANRSNLNRIPVKEGRMSKTNPTDPEILSLSNSSMSSILSGDAFSGSSQNRPRTTAAELTFAGRFNSVSRPDTSNYVNAVQANGQKKICQVNDPPSLDLTIPQMYDDFINNDSSTSCSRLSPYEELEAKPGQNNSKASTEATPKKRGRKKGSKGVDSLIAKESSLSQQILFGSGVKKVKTTKELFNDMQSRKLSISFNRGDSLPAVANKITNTTTLRNLESRSLIARPTSSCSETSIHSPHTLEAYSTNVSQAGTEKLSNILEEPGNTDSDTITSEPSRDSMKSRNIKRMNSLDSNSNSLQTTSVLTSSKDYNDVTTQLMHMVHNLNSPLSVNETEKLYQAQIVPCTCIVVEDIPKESSAHDNIDHSDMEADSINKATCDIETVRDKKHSEQPSLKTDNCDVEEAPLLISQKPIKSIFDLDFDDEDDPLQSIIKNISLPESNLKQDPDDYIKSSFTVRSLTEENKDLKVVSDSYLDQEASNIVLEPISVYTVYEDPDCVAKQRFDVQTNDVTNFHINALHNYYIPNINGNWNSIDSSIVLTTTVMKFLQSLESYTVTDGADVVPKYGSLTYERIRKDLSYLKFDRNWKSKSFKSFIPPFLGVAKCLPTCRLAAKRLKDKTKALSTTKSVETIIKLEEPEIIINYFEKNKGSPSPLRVEVDANGNSGENQAQTQSSEDDPLMNNNATLSFNLLKLVNNNEGRKSIVDDQVNSKPTIDGLDNRKGIRCSSDSSCSNSSLQLTQDSINEKLRNQRNLSLTSEQSQSERNVERNRKKRRKARHAESNDGIDFGNNIEIANTSIDEKPLIKRIKIAINGNVATQRQISGISSSNNSSDDEHDDEVGGEARSEVSDPEVGYNTSGYSQIGLAASDDEQESNRSHSTTIDSIAADDDGHLENEYENSNDEEYAIVQRPMVGVANNHIVLTIKKTPSKMNSPVNSISAISPNVGQASASVAGTLEAHTSKNAHFATTNTDSKIEYPETEIIGEYQRKFSLAPMVFCTDELHRLDPDRPFLTSNTCQNNLKTSYQYCRRRRRLRYRRPRDLICPKETIDIELKHLFNNVTRSTQMLLKPHRKLFFANELCRQDGAGRKERIVNYSSSSSSSSGSCTSNDEDDSDPEEKSKRERKRYSALSEDTEKCQIAVSKTQKLKNETDPNIAAKNINDQEDLYLYSDSDESLNTGEFGNQHNELNDPKLNKQDELPLHNNGMLPSFNFIYNDQQLKASANEVNEKAFEKPSLKLLQIQNCDDVNVCYNNINISVIKSHSLGSVKPINDDDNGKQCVINNLTSESLEKAKNCNPIYTDVSSELMLSQPAIEYRTGIRAVVDDAPSKYGVNTTQIQQFKEWHEVLQLQSYNNEPLIVLPYVVLE
Length1659
PositionUnknown
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.769
Instability index47.86
Isoelectric point5.68
Molecular weight185406.48
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05544
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     342.57|      75|     193|     278|     352|       1
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  278-  352 (123.84/65.33)	KPSQFYFNDGVPQQLT.NANRSN.LNRIPVK.EGRMSKTNP.TDPEILSL.....SNSSM.S.SILSGDAFSGSSQNRPRTTAAEL
  354-  419 (75.60/36.88)	......FA.GRFNSVS.RPDTSNyVNAVQANgQKKICQVN...DPPSLDL.....TIPQMyD.DFINNDSSTSCSRLSPY...EEL
  422-  469 (50.83/22.27)	KPGQ..NNSKASTEAT............PKK.RGRKKGSKG.VDS..LIA.....KESSL.SqQILFGSGVK..............
  472-  551 (92.29/46.73)	KTTKELFNDMQSRKLSiSFNRG...DSLPAV.ANKITNTTTlRNLESRSLiarptSSCSE.T.SIHSPHTLEAYSTNVSQAGTEKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.42|      33|      34|     679|     711|       2
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  649-  679 (46.78/23.14)	KE.SSAHDNI....DHSDMEADSINKATCD...IETVRD
  680-  712 (55.37/28.75)	KK.HSEQPSLKT..DNCDVEEAPLLISQKP...IKSIFD
  713-  748 (28.27/11.05)	LDfDDEDDPLQSiiKNISLPESNL..KQDPddyIKSSF.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.02|      17|      28|    1011|    1027|       3
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 1011- 1027 (30.51/15.12)	LDNRKGIRCSSDSSCSN
 1041- 1057 (27.51/12.95)	LRNQRNLSLTSEQSQSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.03|      22|      33|    1116|    1146|       4
---------------------------------------------------------------------------
 1116- 1139 (33.84/16.18)	SGISSSNNSSDDEHDDEvgGEARS
 1392- 1413 (38.20/13.39)	SSSSSGSCTSNDEDDSD..PEEKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.84|      25|      29|    1290|    1318|       5
---------------------------------------------------------------------------
 1290- 1315 (43.26/32.62)	FCTDElHRLDPDRP...FLTSNTCQNNLK
 1320- 1347 (41.58/19.12)	YCRRR.RRLRYRRPrdlICPKETIDIELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.70|      23|      31|    1199|    1223|       6
---------------------------------------------------------------------------
 1199- 1223 (35.32/29.68)	AIvqRPMVGVANNHIVLTIKKTPSK
 1233- 1255 (38.38/25.34)	AI..SPNVGQASASVAGTLEAHTSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     450.79|     146|     824|       5|     164|       9
---------------------------------------------------------------------------
    5-  164 (229.64/171.58)	QIQQLTSHLSQALDQNYDVVNMEAVLSV.....ICALEGTTITKeqlEATRLAKYINQLRRRTKNDQlarrakSLLKKWREMVGIHQQTTIEP.....QPQPLAHLSFKP........................IVGTHFPETESNT....VEVMVNSTQYTSQSSPPSSQrvntDlHPNVDSSEPHHINFSSLINNN
  808-  991 (221.15/136.54)	HINALHNYYIPNINGNWNSIDSSIVLTTtvmkfLQSLESYTVTD...GADVVPKYGSLTYERIRKDL......SYLKFDRNWKSKSFKSFIPPflgvaKCLPTCRLAAKRlkdktkalsttksvetiikleepeIIINYFEKNKGSPsplrVEVDANGNSGENQAQTQSSE....D.DPLMNNNATLSFNLLKLVNNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.37|      54|     823|     750|     807|      10
---------------------------------------------------------------------------
  750-  807 (82.47/62.01)	VRSLTEEN.KDLKVVSDSYLDQEASNIVLEPISVY.....TVYEDpdcvAKQRFDVQTNDVTNF
 1574- 1633 (80.90/50.18)	INNLTSESlEKAKNCNPIYTDVSSELMLSQPAIEYrtgirAVVDD....APSKYGVNTTQIQQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.73|      45|    1235|     227|     271|      11
---------------------------------------------------------------------------
  227-  271 (76.06/48.24)	SDSDENDSQSQPVNNHQKL..ATVSSSLALP....AVYPRPKKIKKDKKRK
 1463- 1513 (69.67/43.47)	SDSDESLNTGEFGNQHNELndPKLNKQDELPlhnnGMLPSFNFIYNDQQLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.91|      23|      27|    1517|    1539|      13
---------------------------------------------------------------------------
 1517- 1539 (39.23/20.17)	NEVNEKAFEKPSLKLLQIQNCDD
 1545- 1567 (38.68/19.80)	NNINISVIKSHSLGSVKPINDDD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05544 with Med26 domain of Kingdom Metazoa
Unable to open file!