<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05542

Description "Uncharacterized protein, isoform I"
SequenceMQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKVPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQHAAHHHQQHQQQQQQQQQQQQHHQQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY
Length918
PositionKinase
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.814
Instability index51.28
Isoelectric point9.28
Molecular weight101737.74
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05542
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            16|     755.51|      24|      26|     484|     507|       1
---------------------------------------------------------------------------
  260-  283 (36.75/15.68)	H....R....RYHS.E...RKPFMCQVCGQGFTTSQ
  288-  311 (28.59/10.64)	H....G....KIHI.G...GPMFTCIVCFNVFANNT
  316-  339 (44.80/20.64)	H....M....KRHS.T...DKPFACTICQKTFARKE
  344-  367 (55.14/27.01)	H....F....RSHT.G...ETPFRCQYCAKTFTRKE
  372-  395 (54.42/26.57)	H....V....RKHT.G...ETPHRCDICKKSFTRKE
  400-  423 (49.58/23.58)	H....Y....MWHT.G...QTPHQCDVCGKKYTRKE
  424-  451 (44.14/20.23)	H....LanhmRSHT.N...ETPFRCEICGKSFSRKE
  456-  479 (53.35/25.91)	H....I....LWHT.G...ETPHRCDFCSKTFTRKE
  484-  507 (57.08/28.21)	H....V....RQHT.G...ESPHRCSYCMKTFTRKE
  512-  535 (52.17/25.18)	H....I....RQHT.G...ETPFKCTYCTKAFTRKD
  536-  563 (51.12/24.54)	HmvnhV....RQHT.G...ESPHKCTYCTKTFTRKE
  564-  591 (51.24/24.61)	HltnhV....RQHT.G...DSPHRCSYCKKTFTRKE
  596-  619 (54.82/26.82)	H....V....RLHT.G...DSPHKCEYCQKTFTRKE
  624-  647 (49.05/23.26)	H....M....RQHS.S...DNPHCCNVCNKPFTRKE
  652-  676 (43.21/19.66)	H....M...sRCHT.G...DRPFTCETCGKSFPLKG
  681-  707 (30.05/11.55)	H....Q....RSHTkGqecERPFACEKCPKNFICK.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     217.36|      26|      26|     776|     801|       2
---------------------------------------------------------------------------
  132-  160 (35.20/10.22)	ASANAAaaaAAAASAAATAQQQQQQQQAP
  759-  778 (32.11/ 8.66)	KQQQAA........AAVAAQQQ.AAAAAA
  779-  803 (50.03/17.67)	AQQQAA...AAQQQAAAAAHQQHQQQV.A
  804-  824 (37.90/11.57)	AQQQQ.....QQQQAAVAAHQQQQQQ...
  826-  846 (28.79/ 6.99)	QQQQLL...QLSIQHAAHHHQQHQ.....
  860-  879 (33.34/ 9.28)	QQQQ......QQQQSHPQAPPQQQQQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.08|      17|      26|     165|     181|       3
---------------------------------------------------------------------------
  165-  181 (27.72/14.54)	NAGS.........QQGSATVTTTSSG
  183-  208 (20.11/ 8.48)	NGGNggqnnnnnnNNNNNNSTTTTTG
  212-  227 (21.25/ 9.38)	MPKM.........EGGIHGVDGQSS.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05542 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNNNNNSTTTTTGELLMPKMEGG
2) HNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQ
3) HVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMA
4) LLQLSIQHAAHHHQQHQQQQQQQQQQQQHHQQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY
5) MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEM
140
752
83
830
1
218
819
132
918
55










Molecular Recognition Features






MoRF SequenceStartStop




1) QVPIALISD
885
893