<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05536

Description "Uncharacterized protein, isoform H"
SequenceMQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKVPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQHAAHHHQQHQQQQQQQQQQQQHHQQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY
Length919
PositionKinase
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.811
Instability index51.32
Isoelectric point9.28
Molecular weight101808.82
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05536
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            17|     780.63|      26|      26|     559|     584|       1
---------------------------------------------------------------------------
  242-  265 (21.22/ 8.37)	.......HVCDICgkMFQFR.YQLIVHR.RYHS
  266-  293 (29.91/15.33)	E...RKPFMCQVCgqGFTTS.QDLTRHG.KIHI
  294-  321 (28.37/14.10)	G...GPMFTCIVCfnVFANN.TSLERHM.KRHS
  322-  349 (47.39/29.36)	T...DKPFACTICqkTFARK.EHLDNHF.RSHT
  350-  377 (55.74/36.07)	G...ETPFRCQYCakTFTRK.EHMVNHV.RKHT
  378-  405 (54.30/34.91)	G...ETPHRCDICkkSFTRK.EHYVNHY.MWHT
  406-  433 (49.32/30.91)	G...QTPHQCDVCgkKYTRK.EHLANHM.RSHT
  434-  461 (47.77/29.67)	N...ETPFRCEICgkSFSRK.EHFTNHI.LWHT
  463-  490 (56.68/36.82)	G...ETPHRCDFCskTFTRK.EHLLNHV.RQHT
  491-  518 (57.12/37.17)	G...ESPHRCSYCmkTFTRK.EHLVNHI.RQHT
  519-  546 (52.86/33.76)	G...ETPFKCTYCtkAFTRK.DHMVNHV.RQHT
  547-  574 (57.76/37.69)	G...ESPHKCTYCtkTFTRK.EHLTNHV.RQHT
  575-  602 (55.88/36.18)	G...DSPHRCSYCkkTFTRK.EHLTNHV.RLHT
  603-  630 (56.03/36.30)	G...DSPHKCEYCqkTFTRK.EHLNNHM.RQHS
  631-  659 (46.54/28.68)	S...DNPHCCNVCnkPFTRK.EHLINHMsRCHT
  660-  687 (39.19/22.78)	G...DRPFTCETCgkSFPLK.GNLLFHQ.RSHT
  689-  720 (24.55/11.03)	GqecERPFACEKCpkNFICKvPHHSATT.TMHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     175.64|      22|      22|     837|     858|       2
---------------------------------------------------------------------------
  770-  786 (27.55/ 7.08)	AQQQAAA...AAAA......QQQA..AA
  787-  806 (32.26/ 9.58)	AQQ.......QAAAA.AHQQHQQQvaAQ
  807-  826 (40.46/13.93)	QQQQQQQ...A.AVA.AHQQ.QQQ..QL
  827-  851 (41.99/14.74)	QQQQLLQlsiQHAAH.HHQQHQQQ..QQ
  852-  868 (33.37/10.17)	QQQQQQ.........qHHQQQQQQ..QQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.37|      13|     722|     148|     160|       3
---------------------------------------------------------------------------
  148-  160 (27.07/10.36)	ATAQQQQQQQQAP
  872-  884 (27.30/10.52)	QAPPQQQQQQQPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.42|      17|      20|     110|     129|       4
---------------------------------------------------------------------------
  123-  142 (23.68/ 7.21)	NNAAVAAvmaSANAAAAAAA
  753-  769 (26.74/ 7.97)	HNAQQSQ...KQQQAAAAVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.08|      17|      26|     165|     181|       6
---------------------------------------------------------------------------
  165-  181 (27.72/13.80)	NAGS.........QQGSATVTTTSSG
  183-  208 (20.11/ 8.12)	NGGNggqnnnnnnNNNNNNSTTTTTG
  212-  227 (21.25/ 8.97)	MPKM.........EGGIHGVDGQSS.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05536 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNNNNNSTTTTTGELLMPKMEGG
2) HNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQ
3) HVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMA
4) LLQLSIQHAAHHHQQHQQQQQQQQQQQQHHQQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY
5) MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEM
140
753
83
831
1
218
820
132
919
55










Molecular Recognition Features






MoRF SequenceStartStop




1) QVPIALISD
886
894