<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05522

Description Uncharacterized protein
SequenceMAAFGVLSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSAQTGNALPSTPTPQPAAGNPPPSPFSDLLLCPQHRPVVYGLSCILQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPTKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGKENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEEHDRKETEGNSGIKLEDTGLSEPIDIDHNSSMLFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKDKSVEGMLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKXRDDARHTIKKITKDILKVLNRKSTAETGGEEGQKRKKSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIDTIENPSAHNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHLGGVDDLMDDELGARKSGSRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTTNNEMNSLLENIAKATIEVFQQSAETSSASCAGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKXRDRQKQKSELFTTVLDMLSVLINGTLAADMSSISQGSMEXNKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRKVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAAEPAKSDKTSSNPATSTEERKKKQSKTKKRNQSASKTEDFVLGPSRGVSYGVGMPTDLLHHQPGSTMSRXAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPXSGVLPPGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLGYTSYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQTPMMSGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRFQRQGLQQTQQQQQTAALVRQLQQQLSNTQTQQNNNPFGRY
Length1814
PositionKinase
OrganismAmazona aestiva (Blue-fronted Amazon parrot)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Psittaciformes> Psittacidae> Amazona.
Aromaticity0.07
Grand average of hydropathy-0.465
Instability index51.57
Isoelectric point7.52
Molecular weight201287.34
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05522
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.25|      13|      15|    1757|    1770|       1
---------------------------------------------------------------------------
 1767- 1783 (20.17/ 9.78)	QQQQmlrfQRQGL.QQTQ
 1784- 1797 (16.09/12.18)	QQQQ....TAALVrQLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.62|      26|      27|    1672|    1697|       2
---------------------------------------------------------------------------
 1672- 1697 (48.59/24.01)	YSGQPYQNSH..PSS.NPALVD....PVRQMQQ
 1702- 1727 (32.96/13.73)	YVHQQA......PGY.GHTLGNtqrfPHQSIQQ
 1731- 1759 (37.07/16.43)	MSGMNHLGPQgvPSGiRPSQIL....PDQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.01|      15|      15|    1219|    1233|       3
---------------------------------------------------------------------------
 1219- 1233 (27.01/18.43)	SASCAGNGVNNISSS
 1235- 1249 (26.00/17.41)	SATPASNKSKPILSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.98|      15|      16|     680|     694|       4
---------------------------------------------------------------------------
  680-  694 (26.85/16.82)	LEQITSFALG.MSYHL
  696-  711 (23.14/13.46)	LVQHVQFIFDlMEYSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.73|      15|      16|    1046|    1060|       5
---------------------------------------------------------------------------
 1046- 1060 (24.84/16.35)	FAVLKAVFVLGDAEL
 1065- 1079 (27.89/19.31)	FSHLGGVDDLMDDEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.54|      10|      16|    1457|    1467|       6
---------------------------------------------------------------------------
 1457- 1467 (16.54/12.37)	KPkPRSYYLEP
 1476- 1485 (20.00/10.07)	EP.PTPVALEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.29|      21|      26|    1116|    1141|       7
---------------------------------------------------------------------------
 1116- 1141 (30.77/26.78)	RCLKSLCEDSNDLQDPvlsstQAQRL
 1145- 1165 (38.53/21.87)	ICYPHRLLDNEEGENP.....QRQRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.12|      23|      27|     985|    1009|       8
---------------------------------------------------------------------------
  985- 1009 (38.79/28.45)	CSEQDSEP..GARLTCRilLHLFKTPQ
 1013- 1037 (38.33/21.95)	CQQDGNKPtvGIRSSCD..RHLLAASQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.54|      14|      17|    1390|    1406|       9
---------------------------------------------------------------------------
 1390- 1406 (16.85/18.90)	KIAGFDsIFkkEGLQVS
 1410- 1423 (28.68/17.05)	KISPWD.LF..EGLKHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.48|      10|      25|     204|     213|      11
---------------------------------------------------------------------------
  204-  213 (20.46/ 7.35)	AGGHPPHILS
  230-  239 (23.02/ 9.14)	AGNPPPSPFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.71|      16|      27|    1620|    1635|      12
---------------------------------------------------------------------------
 1620- 1635 (30.94/14.77)	SYKPAVYRQQPPVSQG
 1650- 1665 (27.78/12.48)	SYVSHIGLQQHPSQSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.00|      23|     217|     311|     363|      13
---------------------------------------------------------------------------
  337-  360 (37.54/66.81)	HEiSPDDDAVVALLCEWAVSYKRS
  892-  914 (43.46/10.03)	HH.DPDRVNDIAILCAELTGYCKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.82|       9|      17|     854|     863|      14
---------------------------------------------------------------------------
  854-  863 (13.42/ 9.64)	ENPsAHNFTY
  872-  880 (16.39/ 6.77)	ENP.ANRYSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.17|      12|      26|    1565|    1576|      19
---------------------------------------------------------------------------
 1565- 1576 (24.17/15.51)	PVGLYAQNQP.....LP
 1592- 1608 (17.01/ 8.25)	PLGKLVQSRPpxsgvLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.64|      12|      26|     148|     159|      20
---------------------------------------------------------------------------
  148-  159 (22.56/18.59)	KYTVPVMRAAWL
  174-  185 (21.08/16.73)	KYSGEFVQSAYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      22.54|       7|      26|     749|     759|      21
---------------------------------------------------------------------------
  749-  759 ( 8.27/16.38)	LClcivAVLRH
  778-  784 (14.27/ 7.89)	LC....GVVKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.52|      24|      26|    1333|    1358|      22
---------------------------------------------------------------------------
 1335- 1358 (38.63/24.98)	NKRAYMNLVKKLRKELGDRQSDSL
 1360- 1383 (40.88/21.91)	KVRQLLPLPKQTRDVITCEPQGSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.55|      17|      19|    1491|    1508|      23
---------------------------------------------------------------------------
 1491- 1508 (22.57/17.11)	EPAKSDKTSSNpATSTEE
 1512- 1528 (26.98/14.94)	KQSKTKKRNQS.ASKTED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05522 with Med12 domain of Kingdom Metazoa
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