<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05503

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMIGDLLLCGRKRDTEGFGEESREPTTGDNIREFLLSLRYFRIFIALWNIFMMFCMIVLSCFKQCCGLCIGAVDCASAVWGNIHNMVAVLEVISSLEKYPITKEALEETRLGRLINEVRKKTSNEELAKRAKKLLRNWQKLIEPVTQNEAVPRGLPNPPGSANGGAHNCKAEAQLPAVAGSKPISELKSRNDIQKLNSPKPEKLGNRKRKGDHRDGHQGPPPPKVSKASHEVLQNSSPPPTNGIGGSPENFPSPVDVNLHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEEATGPHQPKSPRCSSFSPRNVRHDTFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPLPAKRLEFPQQAVAEVSQHWPEQQVPSESQHRHPAGTLQQHTSPSCKTSSHPGESLTPHTGFSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVTEGGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGLTREVTSDDLDRICEHHWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length670
PositionUnknown
OrganismAmazona aestiva (Blue-fronted Amazon parrot)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Psittaciformes> Psittacidae> Amazona.
Aromaticity0.05
Grand average of hydropathy-0.823
Instability index58.84
Isoelectric point8.50
Molecular weight74507.91
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05503
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     125.01|      17|      17|     408|     424|       1
---------------------------------------------------------------------------
  295-  311 (21.89/ 7.67)	PSSTSS..LLKTAVLQQHD
  328-  345 (20.96/ 7.04)	SSFSPRnvRHDT.FARQHT
  369-  379 (19.84/ 6.27)	PS........PPPSLMQPS
  408-  424 (32.93/15.23)	PSESQH..RHPAGTLQQHT
  426-  442 (29.40/12.82)	PSCKTS..SHPGESLTPHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.29|      33|      80|     155|     191|       3
---------------------------------------------------------------------------
  166-  244 (34.14/21.10)	HNCKAEAQLPAVAGSKPI.SELkSRNDiqklnspkpeklgnrkrkgdhrdghqgppppkvskashevlqnssP.PPTNGIG
  248-  291 (43.15/21.13)	ENFPSPVDVNLHAGPESSrTEL.SEND....................................khnkipvnaVkPHTSSPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.54|      18|      18|     487|     504|       5
---------------------------------------------------------------------------
  487-  504 (31.37/17.29)	KPVRLKER.KLTFDPMTGQ
  506-  524 (26.16/13.33)	KPLTQKDPlQVEIPALTEQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05503 with Med26 domain of Kingdom Metazoa
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