<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05449

Description "Uncharacterized protein, isoform D"
SequenceMNQYQIQQLTSHLSQALDQNYDVINMDAVLSVICALEGTKITKEQLEATRLAKYINQLRRRTTNEHLARRAKSLLKKWREMVGIQQTTFDSQQQLQTQSIEFLKSTTSTPHFDEIVSLLPISSSLPSQEIFSDIHLNIDRSETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTISNKCDVSKKKLNEVSVVIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSEVYSTSNSSMSSILSGDTTFGNSGSKTRSNSSELTFSGRFKSINQVEVLSQNNFTLFSGNNNASTHINELDKPLFEDYNTYDSSASCSRFSSSVDQGKSEKIALQIHRPVDAQCPVLKKTELFHKASDSHGYKKRGRKKGSRGVDAVISKESSSLCQQIFLGSSTVNKVKTTKELFNEIQSRKLTASHSSTFRDKTKCARLKRRTSSCSEASILSPNLMENYSGNVTLMDIDTFSKKIRVSSIFTNSEVVQFPKMLPKIDLISSPISSKKCSFLRMAISA
Length579
PositionUnknown
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.661
Instability index52.38
Isoelectric point9.51
Molecular weight64708.96
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05449
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.47|      14|      51|     105|     118|       1
---------------------------------------------------------------------------
  105-  118 (25.10/15.79)	STTSTPHFDEIVSL
  154-  167 (26.37/16.97)	SNLSSPHHNNINDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     190.92|      43|      51|     302|     344|       2
---------------------------------------------------------------------------
  302-  344 (67.27/40.06)	YSTSNSSMSSILSGDTTFGNSGSKTRSNSSELTFSGRFKSINQ
  356-  395 (64.19/37.85)	FSGNNNASTHINELDKPLFEDYNTYDSSASCSRFS...SSVDQ
  468-  509 (59.46/34.45)	VKTTKELFNEIQSRKLTASHS.STFRDKTKCARLKRRTSSCSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.81|      13|      15|     123|     135|       6
---------------------------------------------------------------------------
  123-  135 (23.23/15.49)	SSLPSQEIFSDIH
  141-  153 (22.58/14.82)	SETPSLSVNSQAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.11|      17|     499|      11|      27|       8
---------------------------------------------------------------------------
   11-   27 (31.99/19.29)	SHLSQALDQNY..DVINMD
  511-  529 (27.11/15.39)	SILSPNLMENYsgNVTLMD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05449 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTI
2) VIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSE
142
225
208
300










Molecular Recognition Features






MoRF SequenceStartStop




1) FLRMAI
572
577