<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05447

Description "Uncharacterized protein, isoform E"
SequenceMNQYQIQQLTSHLSQALDQNYDVINMDAVLSVICALEGTKITKEQLEATRLAKYINQLRRRTTNEHLARRAKSLLKKWREMVGIQQTTFDSQQQLQTQSIEFLKSTTSTPHFDEIVSLLPISSSLPSQEIFSDIHLNIDRSETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTISNKCDVSKKKLNEVSVVIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSEVYSTSNSSMSSILSGDTTFGNSGSKTRSNSSELTFSGRFKSINQVEVLSQNNFTLFSGNNNASTHINELDKPLFEDYNTYDSSASCSRFSSSVDQGKSEKIALQIHRPVDAQCPVLKKTELFHKASDSHGYKKRGRKKGSRGVDAVISKESSSLCQQIFLGSSTVNKVKTTKELFNEIQSRKLTASHSSTFRDKTKCARLKRRTSSCSEASILSPNLMENYSGNVTLMDIDTFSKKIRVPNNIKET
Length546
PositionUnknown
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.749
Instability index52.41
Isoelectric point9.45
Molecular weight61121.64
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05447
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     629.80|     189|     199|     148|     346|       1
---------------------------------------------------------------------------
   59-  142 (54.46/14.36)	......................................................................................................................................RRRTTNEH.LARRAKSLLKKWREmvGIQQTT.FDSQ.QQLQTQSIEFLKSTTSTphFDEIVSllpISSSLPSQEIFSDIHLNIDRSE
  148-  346 (300.84/125.53)	VNSQAHSNLSSPHHN...NINDLNR...RENNSTNSVHSYNRLSQNMSSGpvnpPQQHLINQSLNTISNKCDVSKKklnevSVVIDIVSDSDD....NDNNSSKLVRSDISEPS.....LLMIPSTPSPRLkKNRKDKKNDPILHRPNKKISKKNKD..GFLHTTPADSEVYSTSNSSMSSILSGDTT..FGNSGS...KTRSNSSELTFSGRFKSINQVE
  347-  544 (274.51/101.81)	VLSQNNFTLFSGNNNastHINELDKplfEDYNTYDSSASCSRFSSSVDQG....KSEKIALQIHRPVDAQCPVLKK.....TELFHKASDSHGykkrGRKKGSRGVDAVISKESsslcqQIFLGSSTVNKV.KTTKELFNE.IQSR...KLTASHSS..TFRDKTKCARLKRRTSSCSEASILSPNLM..ENYSGN...VTLMDID..TFSKKIRVPNNIK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05447 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTI
2) VIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSE
142
225
208
300










Molecular Recognition Features






MoRF SequenceStartStop




NANANA