<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05443

Description "Uncharacterized protein, isoform F"
SequenceMNQYQIQQLTSHLSQALDQNYDVINMDAVLSVICALEGTKITKEQLEATRLAKYINQLRRRTTNEHLARRAKSLLKKWREMVGIQQTTFDSQQQLQTQSIEFLKSTTSTPHFDEIVSLLPISSSLPSQEIFSDIHLNIDRSETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTISNKCDVSKKKLNEVSVVIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSEVYSTSNSSMSSILSGDTTFGNSGSKTRSNSSELTFSGRFKSINQVEVLSQNNFTLFSGNNNASTHINELDKPLFEDYNTYDSSASCSRFSSSVDQGKSEKIALQIHRPVDAQCPVLKKTELFHKASDSHGYKKRGRKKGSRGVDAVISKESSSLCQQIFLGSSTVNKVKTTKELFNEIQSRKLTASHSSTFRDKTKCARLKRRTSSCSEASILSPNLMENYSGNVTLMDIDTFSKKIRERSGWNYYFATSFNQSKRRFRTRNSRFKIRFVI
Length571
PositionUnknown
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.06
Grand average of hydropathy-0.765
Instability index53.37
Isoelectric point9.70
Molecular weight64427.35
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05443
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     214.82|      38|      45|     141|     178|       1
---------------------------------------------------------------------------
  141-  178 (64.06/29.01)	SETPSLSVN.SQAH.SNLSSPHHN...NIND.LNR...RENNST.......NSV
  189-  225 (38.25/14.69)	SSGP...VNpPQQHlINQSLNTIS...NKCD.VSK...KKLNEV.......SVV
  248-  286 (44.74/18.29)	SEPSLLMIP.STPS.PRLKKNRKD...KKNDpILH...RPNKKI.......SKK
  299-  342 (40.01/15.67)	SEVYSTS.N.SSMS.SILSGDTTF...GNSG.SKT...RSNSSEltfsgrfKSI
  345-  382 (27.77/ 8.87)	VE.....VL.SQNN.FTLFSGNNNastHINE.LDKplfEDYNTY.......DS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.84|      36|      51|     387|     422|       2
---------------------------------------------------------------------------
  387-  422 (60.19/49.37)	SRFSSSVDQGKSEKIALQIHRPVDAQCPVLKKTELF
  440-  475 (57.65/46.92)	SRGVDAVISKESSSLCQQIFLGSSTVNKVKTTKELF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.21|      54|     495|      11|      70|       3
---------------------------------------------------------------------------
   11-   70 (82.68/78.77)	SHLSQALDQNY..DVINMDavlsvICALeGTKITKEQLEATRLAKYINQLRR..RTTNEHLARR
  511-  568 (87.54/66.17)	SILSPNLMENYsgNVTLMD.....IDTF.SKKIRERSGWNYYFATSFNQSKRrfRTRNSRFKIR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05443 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTI
2) VIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSE
142
225
208
300










Molecular Recognition Features






MoRF SequenceStartStop




1) GWNYYFAT
542
549