<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05442

Description "Uncharacterized protein, isoform C"
SequenceMDGNAQNMFHGNHQGDPYYRYDAAAAAAAAAAANPRAMGPPGGYPPRHRAPHPLQQQPQYPSYQPTAENLYGLGAADHQAAMGLGVGVGVGVGVGVGGMGDLSGWGAAPTGVPGQAAAYPGAGLGAYGHPQAAPPAQQQRQSNASAYRQHMPAYGQQEQQKLAPYGAQQGMMAGYGSQQPPTPQQQQQVQAQQQAQQVQQQQAQQVQQQQQSQQQARLPQHYPQAPGQHPLYPGVGAPAVQAGQPPTPQGYAHSPYGSPMQHQPGRGAPQHVGYGHSGLDPNQASAYGQHVPGAAPPGHHQQQLGAHQQQQLQSQQQAQQVQQQAQQQQQQPHVSLMQQQLPGAGLPPPHMGMPPSYGSHHQQQQQQQQAQQQQQQAAPPYMSKQAAAQLNSSPQYRAPFPQLSPQMSPRPPTMSPHPQMSPRPVGVSPAKPPAPQQAQAQQQVVQQPQQPSQHSIQGMVGLPSPRPQPPSSGAVGGAVGSGSKVPPPVAAPVNTLQALEQMVMPTQAHGLPPMDYPSAYRSAVGPRMPASPQQQQQQQHHQQWGSQHMAAMQQQQQAAAAQQQQQQAQQQAAAQQQQQQQQAAPQQQQAAMLQAQQQHHQQQMSMYGQAMGQQQQQQPQAPQQVVPPVAAQQQPPQQQQQQQQQQQQQQHQQQQQQSLNDQLQHSINDIVGGGNSSGSTTSSQSSQQQQQQLQQSLPSMHHLIQPTLEATQQTQAAQQQQQQQQPQAALTSPHHQQLQHQSPIHQQQSPHHQQQHTLPSYNQSQQQFDPFANILGDNQPPAAQHVSSPAHVSSPIPAQMQQQQSQQQQQQQQQVPPAQQQQQAQVPQQQQQQPPQPTTPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQHVGVDVGLFDNNSMSSNSAAVAAVASNASAAAAALLDSNSQSSNAEFEKNQSESDGLGLGGVVASEPELPQDESSISKTQETSLSTELPAVQEEQLEKPSDDVEQTQISQPLGDMNTSLSEDAKSADEVGEDKSGAVPPMEPPPPQQQQMPPHYPMAPGYDGQNQGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQEIYCMPPGHEHQHQEKLMRLQERLNLLQQHEVNDQCAGGGPQCVLFQSMPPMYGSNPLHNQQMVESPQVSSTTGRGRGKGANKPRKPRAKKGEKVAAVGQDLMDISSNVVVGQANATQSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRIPKDPNKPPRDRTPKSKKPKDPNDPNSTDSPAPTSKKRASTSKKSKKQYGDDGAEQTGEGSEVEDNKPLVPKAESADGEAETTSAVVGVDGESPDYDDIPVSKIPRSANEEEKEPEAGDETVDSVPDSAGDAASTPSRRDRKRSTARSRRNANSEEGGSARRNRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSPPPDSELDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKEKKSSANTANSNAGSDAEKTEPQSGAEGEAGGQEAGEDKSNIAMDESSQLEASSSTSAAAAAAAEKERQSSTDAANAAMSSKPNYVYINTGDEDSMVVQYVLAVRMGKRELIPEKPKEKTPEPKEEKEEEKPEEPEKSDDGEEKPKAEGEDGEAPEGESKPEESKLETESSGMEVDKEETPAENEKSEEDDTSSPKKEEEMEVDEPAEKEAKPEEQAEDDKTEAKSETNEEEKSSDVETAEEAKETESPEEKMEVDETPGSPKPKEESNSEEKSSEETEEEKKDEESAEKEEEKEESKEGDETEKKEEAEKENKPEPVYIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEEEPFNPDFTEVDRVLDMSVHTDENSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPMRCEWKSKKRPHPEQWKKLEKTPVYKAGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEFYYKTETGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKAQHGEDPESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESEKGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYGHEDVMEINSEDSSNENSDEEGGIGLRSRRRKEKRDRNREKKGHDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDIDIEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKDSTGPGTASGSNSGNTTPAHKSSALDGSDKDGGISASAVAAAVSNPTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDLVQQIKDNTPISELPIRPPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAGDDLAVTNLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSHSDSATGTSDKSQAKANGSNNELESAAASASESSSKSKANPSPGNGSDVDATQQDASSEKATESADTSDPDTDNHKNDATVSASGSSGDPADSSSSSQEVGGQAEAEVKTVASNESDNDESEQNQKSKEIEKESKKDDPKEPTAGAAPAGEAGKDDAAIARAEGDNAESCTNNATTNITTTTTTITNTTTTTTTNTTTTTTTNNPSSKAANSKGQNNSTDNANSNSNLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKQQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGTSGAGSSGSAAGQLDPSGRSLQALMQSQGASTSAAAAAAAAAAAAGGSAGQSQQGVGGAGGSVSVTGSGMPAMPSAADISLMLSILNTTDVNQLAQLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLTGYGVDLHLSTPMGGNNASTLTPDWTKFKQMAHLERKSDETLTDYYKVFVTMCKRQAGLKLAESERGLEGIIEEIEKEHAKLILDRLELLSKLREVARNPQLEDRLKLCTMNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKAAAAEKAAADKAVKNEVIDLDDELMTDESVIKKEGTPVKEEIKAEETADKKEAASPEPNTSEEEEPAKVESETEVKDDAVKAEDSEKETEPEAKAGEKEKSPAEADKDASETEESKASEEKMEVEEASIPAENGQEKAEITAESSPEKTPESEEKKSPEDKDKSVEVEEESAKMEVEEAPKADSEDKSPEKAESDAKESEEKTLPKPEEEKPEESKEESKEKSEDSDKEEKKPSAEAPETPEKASPATETEAAATAAKKPAGDQEILDLVAGPTDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPAAVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGKWPVDSKYSAFASCKGVTDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQASQMQQVASSAAASSGATGLSQSLSQSKPVSASTLPLLDANNINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGASAGGVGGLNVPSAGSGLGKKRKRHIAIDVETERAKLHALLNSSTMAPKDWESEIANMEALTGGSSGRGRGSGSSSALSGMQPPPAHQHASLSRQSSGQFSKPAVPALKTPPPSMGAPMDLSSSLPKMNMTEMLKSASNAVAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGSKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSSQQQSNQKPFTITVTTVPGKSKGASSSGGSGAGGSSSASGGGAAGGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKLSSKYSANSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGAGSSSANSRRSNRQQSSSSQQSPSAAQLQKQQQQQQQQQQQQQQQSMAGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSAPSPKPSSMDSYGSSAVKSHGGRPSSNSSNASSSSHTQQQQPNPAQSPAGNSGSSKKSSRQQSAAAAALDQAALQFGSLAGLNPNLLANLPGLGAFDPKNPLAAFDPKNPLLSMPFGGMPGMANIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPSLGGLTGSSGAAGSSKNQGQSGGGSSNSSSSSASKKKQQQQQAQQQAQNEAAQLAAALSASSGGSGGGSSGGAGGKNSAPSASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSHQSQSKSSQSRNASAAANSAASLMNAMASMGGASTATTQSSSASGSGRGRQSSGRSQPQVTPTAADMAQLSSLLMPGADPLLLESLSRMSNMDLAQATRLMSSLGMPPLPGTSSSASGGGGGGSTSSSSASKRSSSQSANDQAKEHQKWLESLARGALPTDLAALQAFSQGKMPSTSSSNTATSSSSSSKSAKSSAAAAAAAAAAAQLPQIPGMTSDFSQAFLAEMAAQAMAAAGGSLPLSGPGSLASLAGLTGGSAGGSSGGASGGGSSSGNSSSSKRQREQDAFKQQMDYYTKTLGLGSGISLIPTSAGGSSSSSVAAAYAAALDAEHQQQQQQKSKRSRSEIHPTKEELAAAALAAGLPLNLGASMSSIEKSLRGGSSSSSSSTPAPMSAEQDKVTLTPLNASGSGSGSGSASGSGSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPAASGNPGSSHGGSVEDLDTAGNTSAANLSGSSSSSAAAAAAAAAAAAAEENRRSSNRLKRPRSGNEQGSVSAEGQPPEKRRELRSTRHTRSSADANSLNLSAGSESGAEERNE
Length5588
PositionKinase
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-0.848
Instability index62.44
Isoelectric point5.28
Molecular weight598795.21
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblMetazoa

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
nucleosome-dependent ATPase activity	GO:0070615	IEA:InterPro

GO - Biological Process
axon guidance	GO:0007411	IEA:EnsemblMetazoa
blastoderm segmentation	GO:0007350	IEA:EnsemblMetazoa
determination of adult lifespan	GO:0008340	IEA:EnsemblMetazoa
heart development	GO:0007507	IEA:EnsemblMetazoa
imaginal disc-derived wing morphogenesis	GO:0007476	IEA:EnsemblMetazoa
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblMetazoa
neuron remodeling	GO:0016322	IEA:EnsemblMetazoa
positive regulation of border follicle cell migration	GO:1903688	IEA:EnsemblMetazoa
positive regulation of organ growth	GO:0046622	IEA:EnsemblMetazoa
positive regulation of receptor localization to synapse	GO:1902685	IEA:EnsemblMetazoa
regulation of synaptic growth at neuromuscular junction	GO:0008582	IEA:EnsemblMetazoa
segment specification	GO:0007379	IEA:EnsemblMetazoa
short-term memory	GO:0007614	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05442
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            12|     438.98|      31|      31|     536|     566|       1
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   38-   64 (33.91/ 8.81)	..MGPPGGYPPRH........RAP.........H.......PLQ.....Q.Q.......PQ.YPS....Y..Q
  149-  177 (32.07/ 7.84)	QHMPAYGQQEQ..............................QKL.apygA.Q.......QGMMAG....YG.S
  306-  331 (31.86/ 7.73)	....AHQQQQ..L........QSQ.........Q.......QAQ.....QvQ.......QQAQQQ....QQ.Q
  360-  383 (40.61/12.34)	HH....QQQQQ............Q.........Q.......QAQ....qQ.Q.......QQAAPP....YM.S
  428-  456 (37.72/10.82)	S..PAKPPAPQQA........QAQ.........Q.......QVV.....Q.Q.......PQQPSQ....HS.I
  547-  574 (48.07/16.28)	QHMAAMQQQQQAA........AAQ.........Q.......QQQ.....QaQ.......QQA........A.A
  575-  608 (37.65/10.78)	Q.....QQQQQQQ........AAP.........Q.......QQQaamlqA.Q.......QQHHQQqmsmYG..
  609-  644 (37.93/10.93)	QAMGQQQQQQPQApqqvvppvAAQ.........Q.......QPP.....Q.Q.......QQQQQQ........
  739-  783 (30.69/ 7.11)	QHQSPIHQQQSPH........HQQ.........QhtlpsynQSQ.....Q.QfdpfaniLGDNQP....PA.A
  784-  812 (40.32/12.19)	QHVSSPAHVSSPI........PAQ.........M.......QQQ.....Q.S.......QQQQQQ.......Q
  813-  832 (29.09/ 6.27)	QQVPPAQQQQQAQ........VPQ.........Q.......QQQ.............................
 1060- 1100 (39.08/11.54)	PPMEPPPPQQQQM........PPHypmapgydgQ.......NQG.....H.M.......PPMMPP....YGgA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     614.94|      64|      64|    3774|    3837|       2
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 1284- 1335 (52.36/17.41)	.AN.ELDTS.TD.GSgKKKKPRK.PRIPKDPNK....PP......................RDRT.PKS.......KKP.....KD.....PNDP.......NS.....tDSP
 1336- 1419 (49.61/16.06)	APT.SKKR.....AS.TSKKSKK.QYGDDGA.......EQ..TGEGSEVEdnkplvpKAESADGE.AETtsavvgvDGE.....SPdyddiPVSKiprsaneEE......KEP
 1554- 1607 (39.06/10.90)	.SA.NTANS.NA.GS.D....................AEKtePQSGAEGE.......AGGQEAGE.DKS...niamDES.....SQ.....LEAS.......SS......TSA
 1679- 1730 (51.37/16.92)	EKPeEPEKS.DDgEE.KPKAEGEdGEAPEGESK....PE........E............S.KLE.TES.......SGM.....EV.......DK........E......ETP
 1731- 1791 (71.87/26.95)	AEN.EKSEE.DD.TS.SPKKEEE.MEVDEPAEK....EAK..PEEQAEDD.......KTEAKSET.NEE.......EKS.....SD.....VETA.......EE.........
 1794- 1841 (43.04/12.85)	..........ET.ES.PEE...K.MEVDET..P...gSPK..PKEESNSE.......EKSSEETEeEKK.......DEE.....SA.....E..K.......EE.........
 3670- 3727 (58.44/20.38)	AAA.EKAAA....AE.KAAADKA.VKNEVIDLD....DEL..MTDESVI...........KKEGT.PVK.......EEI.....KA.....EETA.......DK......KEA
 3728- 3776 (66.85/24.49)	ASP.EPNTS.EE.EE.PAKVESE.TEVKDDAVK....AE........D............S.EKE.TEP.......EAK.....AG.......EK........E......KSP
 3777- 3837 (84.46/33.10)	AEA.DKDAS.ET.EE.SKASEEK.MEVEEASIP....AEN..GQEKAEIT.......AESSPEKT.PES.......EEK.....KS.....PEDK.......DK.........
 3838- 3897 (49.47/16.00)	........SvEV.EE.ESA...K.MEVEEA..PkadsEDK..SPEKAESD.......AKESEEKTlPKP.......EEE.....KP.....EESK.......EE...skeKS.
 3898- 3961 (48.43/15.48)	......EDS.DK.EE.KKPSAEA.PETPEKASP....A........TETE.......AAATAAKK.PAG.......DQEildlvAG.....PTDP.......DDdevmkeKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     588.93|      65|      65|    5279|    5343|       3
---------------------------------------------------------------------------
 4688- 4718 (45.15/11.26)	G.GRP........SSNSSNA.......SSS...SHTQ...........QQQPNPAQ.............................................................................................SP..AG.N
 4855- 4895 (60.77/17.81)	G.GGS........SNSSSS..........SA..SKKK...........QQQQQAQQQAQNE....AAQLAAA.................................................L......................SA........S.S
 4896- 4949 (57.46/16.42)	G.GSG........GGSSGGAggknsapSASQLAAGFP................FLFPNPSLLYP.......PMGLGGL..........................nPY............SL................................GS.S
 4950- 5012 (48.15/12.52)	GlGSAydqlaqqyNLLNGAT.......SSASNTSSTQ...........S....KSHQSQSKSS....QSRNASAAAN..........................................SAA......................SL...MNamAS.M
 5013- 5103 (51.00/13.72)	G.GAS....tattQSSSASG.......SGRG.................RQS...SGRSQPQVTPT...AADMAQLSSL.L.......................M.PGadpllleslsrmSNMdlaqatrlmsslgmpplpgtssSA...SG..GG.G
 5171- 5239 (69.01/21.27)	S.KSA........KSSAAAA.......AAAAAAAQLP...........QIPGMTSDFSQAFL.A..EMAAQAMAAAGG.S...................lplsG.PG............SLA......................SLaglTG..GS.A
 5240- 5292 (69.67/21.54)	G.GSS........GGASGGG.......SSSGNSSSSK...........RQREQDAFKQQMDYYTK.............tL.......................G.LG............SGI......................SL...IP..TS.A
 5293- 5359 (89.21/29.74)	G.GSS........SSSVAAA.......YAAALDAEHQ...........QQQQQKSKRSRSEIHPTKEELAAAALAAGLpL.......................N.LG............ASM......................SS...IE..KSlR
 5360- 5397 (49.39/13.04)	G.GSS........SSS.SST........PAPMSAEQD...........KVTLTPLNASGS..............................................G............SG........................S.......GS.A
 5398- 5485 (49.11/12.92)	S.GSG........SSAAAAG.......LAANLPSQTTitiappissgaSTSSERSERSESRISLTITN...AADAAKL..pppyeeadeliiqpilkkpaasgN.PG............S..................................S.H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     323.59|      61|      65|    2999|    3059|       4
---------------------------------------------------------------------------
 2782- 2828 (37.81/12.53)	.....GKSNKDST.GPgtASGSNSGNTTpaHKSS.......ALDGSDK.....DGGISASA...........VAAA...........
 2976- 2997 (28.84/ 7.41)	D....DGDE...V.................DDDG.......TTTTKD..................................SDSTKL
 2998- 3058 (93.13/44.10)	T....GGDNKDSLLDP..ERPSSSGKSS..HSDS.......ATGTSDKSQAKANGSNNELE...........SAAASASESSSKSKA
 3059- 3106 (56.34/23.11)	N....PSPGNGSDVDA..TQQDAS.......SEK.......ATESADTSDPDTDNHKND..............ATVSASGSS.....
 3108- 3176 (38.65/13.01)	..............DP..ADSSSSSQEV..GGQAeaevktvASNESDNDESEQNQKSKEIEkeskkddpkepTAGAAPAGEAGKDDA
 3177- 3241 (68.83/30.24)	AiaraEGDNAESCTNN..ATTNITTTTT..TITN.......TTTTTTTNTTTTTTTNNPSS...........KAANSKGQNNSTDNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     196.17|      19|      65|     646|     664|       5
---------------------------------------------------------------------------
  179-  192 (26.82/ 6.88)	QPPTPQQQQQVQA........Q
  193-  207 (25.96/ 6.36)	QQAQQVQQQQAQ....Q...VQ
  284-  301 (28.12/ 7.67)	ASA.YGQHVPGAAPPGH...HQ
  403-  419 (26.05/ 6.41)	LSPQMSPRPPTMS.P.H...PQ
  646-  664 (32.49/10.30)	QQQQQHQQQQQQSLNDQ...LQ
  684-  705 (26.94/ 6.95)	QSSQQQQQQLQQSLPSMhhlIQ
  712-  727 (29.80/ 8.68)	QQTQAAQQQQQQ...QQ...PQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     157.44|      28|      29|     867|     894|       6
---------------------------------------------------------------------------
  867-  894 (48.68/20.16)	SNNSSSNS.STNSIVNNQPTSVH....DSNSQS
  895-  920 (39.71/15.03)	SINSSSNN.QQQLLMDNTN.S.H....GGNSES
  933-  964 (34.13/11.83)	NNSMSSNS.AAVAAVASNASAAAaallDSNSQS
  971-  999 (34.93/12.29)	KNQSESDGlGLGGVVASEPELPQ....DESSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.00|      20|      24|    4746|    4769|       7
---------------------------------------------------------------------------
 4746- 4765 (37.61/17.14)	LAGLNPNL.........LANLPGLGAFDP
 4772- 4799 (22.51/11.59)	FDPKNPLLsmpfggmpgMANIPGLGNLN.
 4800- 4815 (22.88/ 8.16)	....NMNL.........FASLAGMGGLGN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.14|      21|      24|    4225|    4245|       8
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 4223- 4243 (34.43/14.59)	GGSSGRGRGSGSSSALSGMQP
 4272- 4290 (27.89/ 9.87)	PPSM..GAPMDLSSSLPKMNM
 4433- 4451 (25.81/ 8.37)	GASSSGGSGAGGSSSASG..G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.13|      26|      29|    3320|    3346|       9
---------------------------------------------------------------------------
 3320- 3346 (44.31/25.95)	PTTPTLQSMqMQLQSGTSGAGSS....GSAA
 3351- 3372 (37.17/16.42)	PSGRSLQAL.MQSQ....GASTS....AAAA
 3380- 3405 (33.65/13.91)	AGGSAGQS.....QQGVGGAGGSvsvtGSGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.17|      17|      18|    1121|    1137|      10
---------------------------------------------------------------------------
 1121- 1137 (35.84/23.66)	QIQEIYCMPPGHEHQHQ
 1142- 1158 (24.33/12.68)	RLQERLNLLQQHEVNDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.43|      14|      71|    1101|    1115|      11
---------------------------------------------------------------------------
 1101- 1115 (26.71/20.34)	PGMYPPYPmLHQQEI
 1173- 1186 (30.71/17.94)	PPMYGSNP.LHNQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     348.39|      90|     106|    4452|    4543|      12
---------------------------------------------------------------------------
 4309- 4368 (33.42/ 7.11)	................................................QDFSM.PSKKSSVHAALSSAFPSMGSKSKLddtlnklmkknncTIEEP..VigkeKKRKKLDE
 4452- 4543 (142.62/63.18)	GAAGGSGLSALQNMAMGGLSSKDSLNAllAQTMATDPQTFLKQ.QQKMMQFLP.PAQRKAYENMLAEMEQAMKLSSKY.............SANSPHDV....KVNKWLSD
 4560- 4628 (115.93/46.75)	GGAGSSSANSRRSNRQQSSSSQQSPSA..AQLQKQQQQQ..QQ.QQQQQQ..................QQSMAGPQNL.............TGEEPVPV.....INKQ.TG
 4629- 4679 (56.41/18.42)	KRLGGNKAPQLKRL.MQWLTENPNYE........VDPK.WLEQmQNPMSAPSPkPSSMDSY..................................................
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     221.48|      27|      47|     461|     487|      13
---------------------------------------------------------------------------
   72-   97 (37.17/12.56)	GLGAADHQAAMGLGVGVGVGVG.VGV...G
  218-  240 (31.63/ 9.40)	.LPQHYPQAPGQHPLYPGVGA..PAV....
  243-  264 (42.02/15.33)	GQP.PTPQGYAHSPY....GSP.MQHQ..P
  265-  281 (26.18/ 6.28)	GRGAPQH...........VGYGhSGLD..P
  461-  487 (48.76/19.18)	GLPSPRPQPPSSGAVGGAVGSG.SKVP..P
  510-  532 (35.72/11.73)	GLP.PMDYP...SAYRSAV..G.PRMPasP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.73|      33|      34|    1420|    1452|      14
---------------------------------------------------------------------------
 1420- 1452 (54.36/33.14)	EAGDETVDSVP......DSAG..DAASTPSRRDRKRSTARS
 1455- 1489 (45.42/26.04)	NANSEEGGSAR......RNRGslSAKALKKRRNRGRIVPES
 1490- 1523 (31.95/15.34)	DGEDDTLDRTPppspppDSEL..DSNKRRSSRNTQR.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     102.89|      25|      25|    2501|    2525|      15
---------------------------------------------------------------------------
 2501- 2521 (25.82/14.05)	.....DGN.NKQLSKKEIEDL..........LKKGAY
 2522- 2548 (28.16/16.16)	GAVMdDDNaGDKFCEEDIDSI..........LKRRTQ
 2590- 2620 (18.17/ 7.11)	.....DID.PDACERDETEDLvlseprrrtqIKRYGH
 2621- 2642 (30.75/18.51)	EDVM.EIN.SED.SSNENSD............EEGGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.91|      17|      23|    1995|    2015|      16
---------------------------------------------------------------------------
 1959- 1990 (24.53/ 7.64)	WKS..LPYEdctweleedvdndkiEQYLRFNKIP
 1995- 2013 (31.38/19.72)	WKSkkRPHP...............EQWKKLEKTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.03|      26|      58|    4030|    4055|      17
---------------------------------------------------------------------------
 4030- 4055 (43.43/25.08)	VDSKY.................SAFASCKGVTDLSIALHESIP
 4090- 4112 (36.49/19.54)	VAS...................SAAAS.SGATGLSQSLSQSKP
 4113- 4151 (20.11/ 6.46)	VSASTlplldanninaavaaavAAAAAGGNATSLS.SL...LP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     387.01|     139|     200|    2044|    2194|      18
---------------------------------------------------------------------------
 2024- 2074 (48.02/38.43)	.......................................................................................................Y...QLEGLNW..........LK...........................FSWYNTHNCILaDEMGLGKTIQSLTFvhS.....VYEYG.IRGPFLV
 2075- 2228 (215.37/189.18)	IAP.........LSTIpnWQREFEGWTDMNVVVYHGSVTS..............KQMIQDY.........EFYYKTETGKvlkEPIKF..NVLITTFEMIVTDYM..DLKAFNWRLCVIDEAHRLKnrnC.KLLEG...LRQLNLEH...RVlLSGTPLQNNIS.ELFSLLNFLEPSQF..SsqeefMSEFGsLRTEEEV
 2251- 2401 (123.63/87.22)	LAPkeetiieveLTNI..QKKYYRGILEQNFSFLKKGTTSanipnlmntmmelrKCCIHPYllngaeeqiQYDFKAQHGE...DPESYykNLILSAGKMVLIDKLlpKLKANGHRVLIFSQMVR.....ClDILEDylvYRKYPFERidgRI..RGNLRQEAI.....................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.00|      11|      23|    2677|    2688|      19
---------------------------------------------------------------------------
 2677- 2687 (20.54/ 7.34)	GLEEIQYGNWA
 2718- 2728 (18.46/11.60)	GWRDIDIEDCA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     187.87|      59|      71|    2832|    2898|      21
---------------------------------------------------------------------------
 2832- 2898 (82.28/77.86)	PTSIHD..PNHWSKKEKYDaDAYLEGAYkKHlGRHANKVLLRVRMLYYIQHevIG.....DLvqQIKdNTPISE
 2903- 2968 (105.59/65.90)	PPPTPDqvPSSWWNPICCD.KSLLVGTY.KH.GCEMYRQMRADPNLCFVTH..VGagagdDL..AVT.NLPINE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.82|      13|      62|    5091|    5110|      23
---------------------------------------------------------------------------
 5091- 5110 (17.92/ 7.25)	LPGTSSsasggggGGSTSSS
 5155- 5170 (18.90/ 8.28)	MPSTSS....sntATSSSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.90|      13|      45|    2691|    2703|      24
---------------------------------------------------------------------------
 2691- 2703 (26.44/17.82)	CFKVEKG...LLSFGW
 2735- 2750 (21.46/12.99)	CLQVYKGdekIKTFIW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.77|      28|      33|    5530|    5557|      25
---------------------------------------------------------------------------
 5530- 5557 (48.83/21.23)	SNRLKRPRSGNEQGS..VSAEGQPP.EKRRE
 5558- 5588 (35.94/13.54)	LRSTRHTRSSADANSlnLSAGSESGaEERNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.63|      29|      33|    1204|    1235|      26
---------------------------------------------------------------------------
 1204- 1235 (43.68/25.79)	ANKPRK.PRAKKGEKVAAVGQDLMDISsnvVVG
 1237- 1266 (45.95/20.86)	ANATQSiPTTQLPVSEDCVTQGAGDTS...VVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.78|      13|      64|    3578|    3599|      27
---------------------------------------------------------------------------
 3578- 3595 (13.63/32.31)	LREvarnPQLEDRlKLCT
 3603- 3615 (27.15/12.64)	WWE....PGRHDK.ELIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.77|      12|      24|    4189|    4200|      30
---------------------------------------------------------------------------
 4189- 4200 (20.36/12.70)	DVETERAKLHAL
 4210- 4221 (22.40/14.87)	DWESEIANMEAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.88|      13|      32|    1003|    1015|      32
---------------------------------------------------------------------------
 1003- 1015 (21.04/13.21)	ETSLSTELPAVQE
 1038- 1050 (20.84/12.99)	NTSLSEDAKSADE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.61|      15|     165|    4245|    4259|      33
---------------------------------------------------------------------------
 4245- 4259 (28.30/15.41)	PAHQHASLSRQSSGQ
 4403- 4417 (27.31/14.49)	PANLQSSSSQQQSNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.16|      15|      65|    1856|    1872|      38
---------------------------------------------------------------------------
 1663- 1677 (24.26/12.24)	EKPKEKTPEPK..EEKE
 1857- 1873 (20.90/17.17)	EAEKENKPEPVyiDVEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05442 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALQAFSQGKMPSTSSSNTATSSSSSSKSAKS
2) AYAAALDAEHQQQQQQKSKRSRSEIHPTKEELAA
3) DLAVTNLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSHSDSATGTSDKSQAKANGSNNELESAAASASESSSKSKANPSPGNGSDVDATQQDASSEKATESADTSDPDTDNHKNDATVSASGSSGDPADSSSSSQEVGGQAEAEVKTVASNESDNDESEQNQKSKEIEKESKKDDPKEPTAGAAPAGEAGKDDAAIARAEGDNAESCTNNATTNITTTTTTITNTTTTTTTNTTTTTTTNNPSSKAANSKGQNNSTDNANSNSNLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKQQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGTSGAGSSGSAAGQLDPSGRSLQALMQS
4) GGVGGLNVPSAGSGLGKKRKRHIAIDVETER
5) GSNPLHNQQMVESPQVSSTTGRGRGKGANKPRKPRAKKGEKVAAVGQDLMDISSNVVVGQANATQSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRIPKDPNKPPRDRTPKSKKPKDPNDPNSTDSPAPTSKKRASTSKKSKKQYGDDGAEQTGEGSEVEDNKPLVPKAESADGEAETTSAVVGVDGESPDYDDIPVSKIPRSANEEEKEPEAGDETVDSVPDSAGDAASTPSRRDRKRSTARSRRNANSEEGGSARRNRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSPPPDSELDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKEKKSSANTANSNAGSDAEKTEPQSGAEGEAGGQEAGEDKSNIAMDESSQLEASSSTSAAAAAAAEKERQSSTDAANAAMSSKPNYVYINTGDEDSMVVQYVLAVRMGKRELIPEKPKEKTPEPKEEKEEEKPEEPEKSDDGEEKPKAEGEDGEAPEGESKPEESKLETESSGMEVDKEETPAENEKSEEDDTSSPKKEEEMEVDEPAEKEAKPEEQAEDDKTEAKSETNEEEKSSDVETAEEAKETESPEEKMEVDETPGSPKPKEESNSEEKSSEETEEEKKDEESAEKEEEKEESKEGDETEKKEEAEKENKPEPVYI
6) KEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSSQQQSNQKPFTITVTTVPGKSKGASSSGGSGAGGSSSASGGGAAGGSGLSALQNMAM
7) KLAAAEKAAAAEKAAADKAVKNEVIDLDDELMTDESVIKKEGTPVKEEIKAEETADKKEAASPEPNTSEEEEPAKVESETEVKDDAVKAEDSEKETEPEAKAGEKEKSPAEADKDASETEESKASEEKMEVEEASIPAENGQEKAEITAESSPEKTPESEEKKSPEDKDKSVEVEEESAKMEVEEAPKADSEDKSPEKAESDAKESEEKTLPKPEEEKPEESKEESKEKSEDSDKEEKKPSAEAPETPEKASPATETEAAATAAKKPAGDQEILDLVAGPTDPDDDEVMKEKEKAVEEECKKQA
8) LNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKLSSKYSANSPHDVKVNKWLSDM
9) LNGATSSASNTSSTQSKSHQSQSKSSQSRNASAAANSAA
10) LQQQIQEIYCMPPGHEHQHQEKLMRLQERLNLLQQHEVN
11) LSEVQDFSMPSKKSSVHAALSSAFPSMGSKSKLDDTLNKLMKKNNCTIEEPVIGK
12) LSGWGAAPTGVPGQAAAYPGAGLGAYGHPQAAPPAQQQRQSNASAYRQHMPAYGQQEQQKLAPYGAQQGMMAGYGSQQPPTPQQQQQVQAQQQAQQVQQQQAQQVQQQQQSQQQARLPQHYPQAPGQHPLYPGVGAPAVQAGQPPTPQGYAHSPYGSPMQHQPGRGAPQHVGYGHSGLDPNQASAYGQHVPGAAPPGHHQQQLGAHQQQQLQSQQQAQQVQQQAQQQQQQPHVSLMQQQLPGAGLPPPHMGMPPSYGSHHQQQQQQQQAQQQQQQAAPPYMSKQAAAQLNSSPQYRAPFPQLSPQMSPRPPTMSPHPQMSPRPVGVSPAKPPAPQQAQAQQQVVQQPQQPSQHSIQGMVGLPSPRPQPPSSGAVGGAVGSGSKVPPPVAAPVNTLQALEQMVMPTQAHGLPPMDYPSAYRSAVGPRMPASPQQQQQQQHHQQWGSQHMAAMQQQQQAAAAQQQQQQAQQQAAAQQQQQQQQAAPQQQQAAMLQAQQQHHQQQMSMYGQAMGQQQQQQPQAPQQVVPPVAAQQQPPQQQQQQQQQQQQQQHQQQQQQSLNDQLQHSINDIVGGGNSSGSTTSSQSSQQQQQQLQQSLPSMHHLIQPTLEATQQTQAAQQQQQQQQPQAALTSPHHQQLQHQSPIHQQQSPHHQQQHTLPSYNQSQQQFDPFANILGDNQPPAAQHVSSPAHVSSPIPAQMQQQQSQQQQQQQQQVPPAQQQQQAQVPQQQQQQPPQPTTPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQHVGVDVGLFDNNSMSSNSAAVAAV
13) LTGSSGAAGSSKNQGQSGGGSSNSSSSSASKKKQQQQQAQQQAQNEAAQLAAALSASSGGSGGGSSGGAGGKNSAPS
14) MASMGGASTATTQSSSASGSGRGRQSSGRSQPQVTPTAADMAQLSSLLMPGADPLLLESLSRMSNMDLAQATRLMSSLGMPPLPGTSSSASGGGGGGSTSSSSASKRSSSQSANDQAKEHQKWLESL
15) NPRAMGPPGGYPPRHRAPHPLQQQPQYPSYQPTAEN
16) QLSIDYVGGGGAGSSSANSRRSNRQQSSSSQQSPSAAQLQKQQQQQQQQQQQQQQQSMAGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSAPSPKPSSMDSYGSSAVKSHGGRPSSNSSNASSSSHTQQQQPNPAQSPAGNSGSSKKSSRQQSAAAAA
17) RYGHEDVMEINSEDSSNENSDEEGGIGLRSRRRKEKRDRNREKKGHDE
18) SAGGSSGGASGGGSSSGNSSSSKRQREQDAFKQQM
19) SMSSIEKSLRGGSSSSSSSTPAPMSAEQDKVTLTPLNASGSGSGSGSASGSGSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPAASGNPGSSHGGSVEDLDTAGNTSAANLSGSSSSSAAAAAAAAAAAAAEENRRSSNRLKRPRSGNEQGSVSAEGQPPEKRRELRSTRHTRSSADANSLNLSAGSESGAEERNE
20) SNASAAAAALLDSNSQSSNAEFEKNQSESDGLGLGGVVASEPELPQDESSISKTQETSLSTELPAVQEEQLEKPSDDVEQTQISQPLGDMNTSLSEDAKSADEVGEDKSGAVPPMEPPPPQQQQMPPHYPMAPGYDGQNQGHMPPMMPPYGGAPGMYPPYPMLHQQEI
21) VQKISRDHSGLHNLVPRGRNGGKSNKDSTGPGTASGSNSGNTTPAHKSSALDGSDK
22) WESEIANMEALTGGSSGRGRGSGSSSALSGMQPPPAHQHASLSRQSSGQFSKPAVPALKTPPPSMGAPMDLSSSLPKMNMTEMLKS
5146
5303
2958
4164
1177
4377
3668
4476
4965
1118
4305
102
4838
5009
34
4551
2617
5238
5350
948
2761
4211
5176
5336
3362
4194
1869
4467
3971
4544
5003
1156
4359
946
4914
5135
69
4735
2664
5272
5588
1115
2816
4296










Molecular Recognition Features






MoRF SequenceStartStop




1) AAAAAAAAAAAAEENRRSSNRLK
2) DYPSAYRSAV
3) KRRELR
4) LSAKALKK
5) PYEEADELIIQPILKKP
6) TETEAAA
7) VMLRF
8) YRYDA
5512
515
5554
1471
5459
3922
1530
19
5534
524
5559
1478
5475
3928
1534
23