<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05436

Description Mediator of RNA polymerase II transcription subunit 24-like
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKRNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYSISSQFDDFSRELCVKSLLEIMEMFIHRLSCHGKAEECISLCRALLAAVVWLLQGCAWYGERIREQGEGAGGEISLRACQERLEGLLLSTKNRALIYIARLEEQTSWSNVEQAVVRVSESLSGFTNQTLKGKLEECLSLVKSIPQMLAVQSDPPQHTNFPSVHAFIMLEGTMNLTGEIQPMVEQLMMIKRMQRIPAPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGEKDFMEDVNVAFEYLLKLTPLLDKADQRCNCDCLSLLLQECNKLGLLSESNTANLTAKRAEDREYAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPEPGKVESLVALLNNSSEMKLVQMKWHEICLCTPAAVLEVLNAWENGVLSVESVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPLYGENMLQFYNERVLIMNSILEHMCADVFQQTGVALRPAMEGQEPMPYRGLLPPREPICGALSRQFRAALRKGWVDSRALHLFESLLQMGGVFWFTNNLVKELLKETRKEWATRAVELLYSIFCLDTQQITLTLLGHILPRLLTDPAHWHSLADPPGKALAKLADYNSLFPLDDTQPSKLMRLLSSHEDEPSVLSSPGDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGAKTAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELVKLPGLAQPRVVLAITDLTLPLGRRVAAKAIATL
Length945
PositionTail
OrganismScleropages formosus (Asian bonytongue) (Osteoglossum formosum)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Osteoglossocephala> Osteoglossomorpha> Osteoglossiformes> Osteoglossidae> Scleropages.
Aromaticity0.07
Grand average of hydropathy-0.024
Instability index43.84
Isoelectric point6.31
Molecular weight105736.07
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05436
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.85|      16|      29|     379|     394|       2
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  379-  394 (27.33/16.91)	LKTAENANIQPNPGLI
  405-  420 (26.52/16.19)	LKTVDADHSKSPEGLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.57|      11|      29|     291|     301|       3
---------------------------------------------------------------------------
  291-  301 (19.61/13.38)	AFTF.LKIPQVL
  321-  332 (14.96/ 8.29)	AFEYlLKLTPLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.27|      29|      35|      98|     132|       5
---------------------------------------------------------------------------
   98-  132 (47.53/46.23)	HGKaeecisLCRALLAAVVWLLQGCAWYGERIREQ
  594-  622 (51.74/34.73)	KGK......VCSMAICAVAWLVAHVRMLGLDEREK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.11|      26|     202|     142|     170|      14
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  142-  170 (30.92/29.64)	LRACqERLeGlLLSTKNRALIYIARLEEQ
  348-  373 (44.19/26.00)	LQEC.NKL.G.LLSESNTANLTAKRAEDR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05436 with Med24 domain of Kingdom Metazoa
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