<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05407

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMNQGQGNVHFNVPNNFSPAHMSQQSQQGGIMHLPQHSPMAQQQQNIPQQLMQQSQPQLMQQQLTAQQQQLQQQQQGQEMLLPQSQMMQQSQPQLMQQQLMAQQQQLQQQQLQQQQQQGFQHSPAPQMQQQRYLQQHQQQQGNIFQHPQQHSPAPQQGNATSVMQQQPFIQQQQHQQMHQQQQQPQQHPQQQPQQQPQQQPQKDFNPASLCRIGQETVQELVSRVQECLQHLKNLQPPNGSAQSTSLAVDKKNKLDDQLKMVKVLFKRLRIIYNKCNENSQELDSFPLDTMIPTQSNLVDWKYADKTKSEQYLAAVEEKKELYEQIAVKNRHLQDIMEYMRSIIWEINTMLMMRRP
Length355
PositionHead
OrganismDaphnia magna
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.05
Grand average of hydropathy-1.172
Instability index96.66
Isoelectric point8.39
Molecular weight41686.47
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05407
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     223.01|      34|      34|      41|      74|       1
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   41-   73 (64.03/13.84)	..QQQQNIPQ.QLMQQS.QPQLMQQQLTA....QQQQLQQQ
   74-  109 (56.37/11.08)	QqGQEMLLPQsQMMQQS.QPQLMQQQLMA....QQQQLQQQ
  137-  171 (45.97/ 7.33)	Q.QQQGNIFQ.HPQQHSpAP....QQGNAtsvmQQQPFIQQ
  172-  199 (56.64/11.17)	Q.QHQQMHQQ....QQ..QPQQHPQQ..Q....PQQQPQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.75|      14|      19|       1|      18|       2
---------------------------------------------------------------------------
    1-   15 (22.10/ 8.95)	MNQ..GQGNVhFNVPNN
   21-   36 (23.65/10.35)	MSQqsQQGGI.MHLPQH
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.55|      35|      47|     217|     251|       3
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  217-  251 (58.16/36.07)	VQELVSRVQ....ECLQHLKNLQ..PPNGSAQSTSLAVDKK
  261-  301 (50.39/30.23)	VKVLFKRLRiiynKCNENSQELDsfPLDTMIPTQSNLVDWK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05407 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MNQGQGNVHFNVPNNFSPAHMSQQSQQGGIMHLPQHSPMAQQQQNIPQQLMQQSQPQLMQQQLTAQQQQLQQQQQGQEMLLPQSQMMQQSQPQLMQQQLMAQ
2) QLQQQQQQGFQHSPAPQMQQQRYLQQHQQQQGNIFQHPQQHSPAPQQGNATSVMQQQPFIQQQQHQQMHQQQQQPQQHPQQQPQQQPQQQPQKDFNPASLC
1
110
102
210










Molecular Recognition Features






MoRF SequenceStartStop




NANANA