<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05339

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMSDDDMHADGEDPLAAYPLPSIPVNQGPPFIAFAVLLDFAVQKAFQDLTILADLLPKKSDLERKTSIAQFANGTRQLFIRVLAILKWARCGAKVDMCTGIQCFLDQQASMFVDTADRLFQLCNSVLLNARLPAFQVPIAVDVLTLGTYPRLSKAIEQRFVPPEKITPSELQSVTRRLNQIVKRRIISQLAVLPKRMRSFEVSDGMVTFRVAGEFEATLTLLGQLPVTPWTLLNFRILVADPRVTDGAELLNAYQVAFLHQYLQGKLNIAKEPLVELYNLLHSFCLSIQLDLLFCQTHRLLGEYMSSSLAVEEYVKSERLVVTYWREDQARPRREFTRVQDALPKASSSYKMIIYVDQDNPQRGLQVLHMPKSDLLLPSLDGRSRLSFEDLLSDTVLVRIGYRLRHLRELIEDVSDCRCNIQGRFPKLRIALLDDCDSSEIVYTSINLFSGRFVVKLAAIGDSPDRRAFEDLINKGNWDELRNTLVKLRVNLVVSRCVRTMRLFPMSLCTAVPSCVAASFPAITSDKWLAIELKRYECIYLVVDLRQQVESGHVGLHCWIVSSELPLVRLSAVPDGVNVEKFEVNLNNVVPVALSHFSTRETEAAAEMAKRQEEIHFSSYNSRLAGFFALCEQVASFLVLMGEFDHRGIRYCFHSLRECFGSKLEIVGIDYTVIADPTDVQLFKLILDAISRITVRMSYDRHKLHWTFECSFFDSPMHYLEHHVAAQSAVGGNTAVLNYPVVKDNVTKVVDEFFNVLRSFAKLYESFLTLAALLGSTPDPSPINIITYTYHKLTFSYGPSLSYVCSLHWKSGAGFSLSFGVCKGVACKSNPHSLLSYQLHQWLQEKPSLVALVRVLNASAVPLDALVACPSTVVLNAIEHHNTPVALNHVFCLIPLSPFVVRLLYKGRICLEISFVSEDHVTIRDCASTFVHPPSRLTQRYVPVVGLKTFLNMHSTDGKRPAQTEDVPAIGDGHQAAAFPNEPALNSVDSSCPPTCDDAAGTSSDIVTSTPPEDWTPSVVPITVKHTTITSICSPSCAAPKPEWSHLHKFLASVSVLDKFKDQTGVSVVRPGHICFKMQQWELRFFINEHTLSSLGLKLCPDDKEMCSEADVHFLENYFAACVSPLYSYNAVTSFARLISACGCIRRDLLSNLLLLMNFQLNRYPEEGVYWFPEICFLVPPMQLIAPPVCTVSKLSSMLNSLAVVANHNTKKVLVWIKFTRVDNPSQSLAFPLLYDGDTNALQIFRGPTGQSAAPVQGGTLCAVDSCLLRQQQVHQNYGDCSVWTSIRDVMHTNDLLAPVNS
Length1301
PositionTail
OrganismTrichuris muris (Mouse whipworm)
KingdomMetazoa
Lineage
Aromaticity0.09
Grand average of hydropathy0.078
Instability index46.20
Isoelectric point6.56
Molecular weight145535.43
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05339
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.17|      48|     150|     145|     200|       1
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  145-  200 (61.25/71.59)	LGTYPRLSKAIEQrFVPPEKITPS...ELQSVTRRlnQIVkrRIisQLAvLPKRMRSFE
  300-  350 (76.92/54.46)	LGEYMSSSLAVEE.YVKSERLVVTywrEDQARPRR..EFT..RV..QDA.LPKASSSYK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.03|      38|     150|    1011|    1053|       2
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 1011- 1053 (64.05/41.12)	PED...WTPSVVPITvkhTTITSICSPSCAAPKpeWSHLHKFLASV
 1164- 1204 (63.98/29.87)	PEEgvyWFPEICFLV...PPMQLIAPPVCTVSK..LSSMLNSLAVV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.98|      15|     157|    1095|    1121|       3
---------------------------------------------------------------------------
  709-  725 (26.07/ 6.32)	CSffDSPMHYLEHHVAA
 1106- 1120 (28.91/11.45)	CS..EADVHFLENYFAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.58|      31|     156|     232|     289|       6
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  249-  289 (39.80/64.74)	LLnAYQvafLHQYLQgklniAKEPLVELYNLL................................HSFCLsIQL
  833-  895 (43.78/14.90)	LL.SYQ...LHQWLQ.....EKPSLVALVRVLnasavpldalvacpstvvlnaiehhntpvalnHVFCL.IPL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.89|      12|      78|     380|     391|       7
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  380-  391 (21.49/12.01)	DGRSRLSFEDLL
  461-  472 (22.40/12.83)	DSPDRRAFEDLI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.77|      26|     232|     396|     459|       8
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  396-  425 (38.35/91.73)	LVRIGYRLRHLR.ELIedVSdcRCNIQGR.FP
  477-  504 (39.42/ 9.90)	WDELRNTLVKLRvNLV..VS..RCVRTMRlFP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05339 with Med14 domain of Kingdom Metazoa
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