<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05330

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMGDSDSYGGLALLLRTINSESTSLIDFIWQCAKAVETTSIISTCLGVMFGVAVLMCYFGLHYLEECPIREEIPLYLLVGGSCLLLVTAMLFCSHAKLMGDNEHREELEMIATENAYPDSSQANFRFSSKAARNMKIFLVVAYVLWFFLGNYWVFSVYLPPFSQPLRSPTPQKFSIVNCLNCSVHGGNGEHVCASCTGARLQWNPTYQNFSGMNLLSYYGLDHAWNKFCNNKKLKEELSAFLPNLPGNIDVAGHKDGSSLRQLIEKPPICGKEILPLGNAETAGFRLLPGSIPEEYRTWNVGPSNSVDKKKRKRKHENIITEEEKKKKKKDKKRKKMMETENPDASASATQVTDFLNF
Length357
PositionHead
OrganismTrichuris muris (Mouse whipworm)
KingdomMetazoa
Lineage
Aromaticity0.10
Grand average of hydropathy-0.229
Instability index45.74
Isoelectric point8.17
Molecular weight40083.74
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05330
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.19|      16|      34|     168|     185|       1
---------------------------------------------------------------------------
  168-  185 (27.92/22.25)	PTPQKFSIVNCLncSVHG
  204-  219 (33.27/18.83)	PTYQNFSGMNLL..SYYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.15|      16|      17|     308|     323|       2
---------------------------------------------------------------------------
  308-  323 (25.83/16.83)	KKKRKRKHENIITEEE
  326-  341 (26.32/17.24)	KKKKDKKRKKMMETEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.51|      11|      33|     244|     254|       3
---------------------------------------------------------------------------
  244-  254 (21.57/15.74)	LP.GNIDVAGHK
  274-  285 (16.93/10.83)	LPlGNAETAGFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.08|      22|      34|      52|      74|       4
---------------------------------------------------------------------------
   52-   74 (37.23/22.03)	AVLMCYFGlHYLEECPIREEIPL
   88-  109 (39.86/19.95)	AMLFCSHA.KLMGDNEHREELEM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05330 with Med19 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TWNVGPSNSVDKKKRKRKHENIITEEEKKKKKKDKKRKKMMETENPDASASATQVT
297
352










Molecular Recognition Features






MoRF SequenceStartStop




1) KKRKRKHENIITEEEKKKKKKDKKRKKMMETENPDASASATQ
309
350