<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05327

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMEEDWRSQRQREKIIQHLDNVIRNCKVPLNIPGDARQVENAVFMKASNKEEYMHYVSKIIYHASSGAAVVGNQMACSSQQGQMNTMQYGGMPAPATPMNQVHPETMAVNDMRGMTHQQQQQQAPPQQQQQQQQQQQQQQQQQQQQHRPTNQMYHGLRPEMQRMIRPMQQSNMQVHHMQASSVNAMQNIQMSGQPQAQNVMMLLQSGGANRQAMVSMQSRPVPSELQLFVQQLPINVRQQLSQLPPEEQSEMLKKLYESKRWQDQQAQQQRQMQQMPQAQIHQNILRQPQPYSGGRPAQPVQMMQPMMQGSTTVRYVEQPPTPYSRPPLTPMPATPAPQQVTIQPASISSVPVPSPSFTPIGQYPTPSPSSGMPTMGPSPVYAMETSPAFAPAPTPGAPVSNKGPSPAGADAAGSSDQPGYREKVIELLVYLDTLKRIIDQQQREGTTPAKFRSSSEWWTYWRGVKRPAWMCC
Length472
PositionTail
OrganismTrichuris muris (Mouse whipworm)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.857
Instability index85.18
Isoelectric point9.45
Molecular weight53237.90
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05327
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     138.07|      22|      22|     334|     355|       1
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  300-  332 (30.34/ 7.51)	VQMMQpmmqgsttvrYVEQPPTPYSRPPlT....PMP
  334-  355 (38.42/11.29)	TPAPQ..........QVTIQPASISSVP.V....PSP
  358-  379 (35.93/10.12)	TPIGQ..........YPTPSPS..SGMP.T..mgPSP
  381-  406 (33.38/ 8.93)	YAMET..........SPAFAPAPTPGAP.VsnkgPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     165.96|      35|     127|     134|     168|       3
---------------------------------------------------------------------------
   80-  115 (46.23/10.89)	QGQMNTMQYGGMPAPATPMNQV.H..PEtMAvNDMRGMT
  134-  168 (69.07/19.68)	QQQQQQQQQQQQHRPTNQMYHG.LR.PE.MQ.RMIRPMQ
  262-  298 (50.66/12.60)	QDQQAQQQRQMQQMPQAQIHQNiLRqPQ.PY.SGGRPAQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.91|      23|      36|     177|     199|       4
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  177-  199 (38.17/14.35)	MQASSVNAMQNIQMSGQPQAQNV
  203-  225 (35.74/13.01)	LQSGGANRQAMVSMQSRPVPSEL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05327 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) VGNQMACSSQQGQMNTMQYGGMPAPATPMNQVHPETMAVNDMRGMTHQQQQQQAPPQQQQQQQQQQQQQQQQQQQQHRPTNQMYHGLRPEMQRMIRPMQQSNMQVHHMQASSVNAMQNIQMSGQPQAQNVMMLLQSGGANRQAMVSMQSRP
2) VRQQLSQLPPEEQSEMLKKLYESKRWQDQQAQQQRQMQQMPQAQIHQNILRQPQPYSGGRPAQPVQMMQPMMQGSTTVRYVEQPPTPYSRPPLTPMPATPAPQQVTIQPASISSVPVPSPSFTPIGQYPTPSPSSGMPTMGPSPVYAMETSPAFAPAPTPGAPVSNKGPSPAGADAAGSSDQP
70
236
220
418










Molecular Recognition Features






MoRF SequenceStartStop




1) WWTYWR
457
462