<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05321

Description Mediator of RNA polymerase II transcription subunit 4
SequenceMETPKRTNDVLSVKTLINDVLNDLDLICRVVAEFVTVPKEQRRFGSTLKTGVLADLFLLKAAELEDLWRVAAEQTDRQKLIDCIQHDIEVRNEYIDRLRGCLLEAESVLMNAIFQANLKLKSIKQADLRPVSPDDLVRYAHRISAANSVTAPLTWQQGDPERPFPTDMEMRSGWLSRITGSSEFSAPISTLVHPPVMSSHIGSVDGVHSVPLPNQNDVSPVAPPKLGPTSCWPSPRSAYMSSPRARLANACPSPGGVQIGQRTVRTPTVHNQAVKREIGSTVEDAVEALSSDSSSSSSSDSPS
Length303
PositionMiddle
OrganismTrichuris muris (Mouse whipworm)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.297
Instability index60.97
Isoelectric point5.91
Molecular weight33101.12
Publications









Function






Annotated function


ECO:0000256	

GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05321
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.62|      14|      79|      87|     100|       1
---------------------------------------------------------------------------
   87-  100 (24.72/14.31)	DIEVRNEYIDRLRG
  167-  180 (26.90/16.05)	DMEMRSGWLSRITG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.02|      13|      29|      15|      27|       2
---------------------------------------------------------------------------
   15-   27 (22.26/17.59)	TLINDVLNDLDLI
   47-   59 (21.75/17.03)	TLKTGVLADLFLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.57|      13|      21|     219|     235|       3
---------------------------------------------------------------------------
  219-  235 (13.07/18.25)	SPVAppKLGpTSCwPSP
  242-  254 (25.50/10.74)	SPRA..RLA.NAC.PSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05321 with Med4 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSVDGVHSVPLPNQNDVSPVAPPKLGPTSCWPSPRSAY
2) SPRARLANACPSPGGVQIGQRTVRTPTVHNQAVKREIGSTVEDAVEALSSDSSSSSSSDSPS
202
242
239
303










Molecular Recognition Features






MoRF SequenceStartStop




NANANA