<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05287

Description Uncharacterized protein
SequenceMALIAALKYDDTKKEGDRLRDISPCISECERLFHIIYKYLTSKSLEHLFQENLDFIERNQKLTIIECYRLLEHMSDNDKRGLALKFCIENLQMCEEIKGRQFEFEEILTFIINKLYKNQLLHHFHCFELHVLNTDYKLKTPIDKRKFTFMKENIHLLDYKEKRNIMKSLLVEKFEHIPMHLTEIQRQQVLPIEELILEIIDRENNYIPPLFTITEVFRLTLTSTAYLFPRVSKKLVNMMSSFRPLAEMITPIGRPWLFPIVSHIGYNSSNNTWKLTDGPVNKIVSKAHLPYSTEYMTSQSYFLYTVLKQPRGNVMMKSMLAKTNSIGPNNKLNITELLQLFILEAMYECEITTLPTHHPAVQYTWLNLQHLSEFCLFHSNVFFLDLLKLLRKSLMELKYRKARDELMWLFLQHVTINVGKFHRECMIEIAEIYKILYTGNEAWVGSSLDVMKMIKFFAPAAIWVCYEKDNKEEFPKPNSIIKNHMELFKREAEKGSELHDGMLIVIGNAISTDKVNFQEKFYKVLMKQLQGNEDEEKWLLPYGRKVDKRLKAIELTSLDCFTFHAKDMTVKHLMYLFGPSNPTLYTVSPAIIESLIRIIISVEVFDSTKFQFLNMLGYYVKNDDLDLTYVIAEAICFRIIDIHMHYSQRVTVVRSVIEGLRRLTPQDSSNYMYFILEQLFIRTFMWCNQHDMCQLLIKSLNDKTIGINSHICSSVSQFTGDINNISMLISPEVVKMLYFIFMKNIKLTGIDIPLELAKTISENYRFSPSIAKHLYNNPEDLNSQMTIEDNNLNMLIDLINNDPLLKEIKFPEEYLSKYRDKYILFCVIFKFLEDNPDAEFNPCFYKILTHFNPKEIVLLCNTFIEYLIYRFKNVEKEESEKLIKIVNDMIFKHQITTLDKFLTALVMHPNDDSTNITSLDILYYLLTTCNDLQQKLNACLSFIPRREFVCRADSEKFFKKMSLYHKNFPEYTYKELLQKLEKKEDFTIPELHLPIYYKNLAELILPTIDMMFTKAILLNYNFERFVVILKMFSPIYAYHPAPLSFVYGILFLLNCSQIEDPGVFQVFTKKIMSISQSVKSFTAEFYDNDYFIYSSAYQTCTEIVGKLVEACNIKLIPPKYVSRDWRFSEFAPAGQALYTGAIELMFTNFPPEIIAESLLDIAIPRSGENYHEKINAACSILTVLPMKYQEYIFTFMQNAITSKELVCCESPELVFSKIEDIIYHCHDNDFIPHLAVIQTFWQLASMAMYTKGIDFFGEVIVNLVTNESQLLYTARIILPFIVKMSEARDKFKKDETIKCTIALYDMIGKICGNTETPIVYKSLICDIMYFIKYMFIGDVVKEKAEDVIKKMPKHMQELMKFYNSTGSNVEGSGKLSNTSISLLANQNRLLQRFPAPLDSEEIFSDQDNTANNHFDMLNSVQFNRNMNHQLPQVYENIINKSDTTENRMPHPQSTEYKNSQLQQHLLNSQYPYNNPNQGNVLNANQRLQMEGRPDHGQVPRSEGVPSHMMPSQKMPQMGMPPNQNVGSQIPMQPGQNMFPGDPRLQQDIRMQQKQQAFQHQYNLHQSMQNKQQMSHQSNVNQSTNQPMNPYNNPSQYHNVMHGQGIPYNQHMPGKQQQIQPPPGMGPNFNMPPGMNMYNNTQQYPPNMMHHPGMGMHPGVQNPHNIPQQGISPIYPQGHMYQGMPTQQQYPPSHLQGHGYNQQRM
Length1704
PositionTail
OrganismStrongyloides papillosus (Intestinal threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.11
Grand average of hydropathy-0.295
Instability index50.96
Isoelectric point6.62
Molecular weight199087.45
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05287
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     119.46|      19|      22|    1616|    1634|       1
---------------------------------------------------------------------------
 1423- 1437 (20.03/ 6.66)	..NRNMNHQ..LPQVY..........ENI
 1520- 1548 (22.65/ 8.71)	PPNQNVGSQIPMQPGQnmfpgdprlqQDI
 1586- 1599 (19.87/ 6.53)	.P...MNP.YNNPSQY..........HNV
 1600- 1618 (28.98/13.67)	MHGQGIPYNQHMPGKQ..........QQI
 1619- 1642 (27.93/12.85)	QPPPGMGPNFNMPPGM....nmynntQQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.82|      14|      44|     365|     378|       2
---------------------------------------------------------------------------
  365-  378 (29.55/20.39)	WLNLQHLS.EFCLFH
  408-  422 (24.26/15.28)	WLFLQHVTiNVGKFH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.95|      12|      47|    1643|    1654|       3
---------------------------------------------------------------------------
 1643- 1654 (29.24/18.45)	YPPNMMHHPGMG
 1674- 1684 (24.55/14.04)	YPQGHMYQ.GMP
 1689- 1698 (22.16/11.79)	YPPS..HLQGHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.80|      41|      47|      97|     143|       4
---------------------------------------------------------------------------
  100-  135 (57.34/31.33)	.......RQ....FEF.EE...ILTFIINK....LYKNQLLHHFHCFELHVLNTD
  138-  180 (25.50/15.37)	LkTPIDkRK....FTFmKEnihLLDY...KekrnIMKSLLVEKFEHIPMH.....
  181-  225 (49.96/21.12)	L.TEIQ...rqqvLPI.EE...LILEIIDR..enNYIPPLFTITEVFRLTLTSTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     418.00|     118|     128|     907|    1034|       5
---------------------------------------------------------------------------
  907- 1034 (187.45/143.29)	MHPnddstniTSLDILY..YLLTTCNDLQQKLN.AC..LSFIPRReFVCRADSEKFFkKMSLYHKNFPEYT..YK...ELLQKLEKKE........................DF.TIPELHLPIYYKN...LAELIlPTIDMMFTKAILLNY.NFERFVV...ILKMFSP
 1038- 1164 (156.46/97.11)	YHP.......APLSFVYgiLFLLNCSQIED..P.GV..FQVFTKK.IMSISQSVKSF.TAEFYDNDYFIYSsaYQtctEIVGKLVEAC........................NIkLIP....PKYVSRdwrFSEFA.PAGQALYTGAIELMFtNFPPEIIaesLLDIAIP
 1171- 1263 (74.09/39.73)	............................HEKINaACsiLTVLPMK.....................YQEYI..FT...FMQNAITSKElvccespelvfskiediiyhchdnDF..IPHLAVIQTFWQ...LASM......AMYTKGI..DF..FGEVIV...NL.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.29|      29|     128|     596|     637|       6
---------------------------------------------------------------------------
  596-  624 (50.88/22.75)	IRIIISVEVFDSTKFQFLNML....GYYVKNDD
  725-  753 (37.68/13.07)	ISMLISPEVVKMLYFIFMKNIkltgIDI....P
  792-  803 (11.72/14.65)	.................LNML....IDLINNDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.20|      29|      42|    1445|    1478|       7
---------------------------------------------------------------------------
 1445- 1478 (43.69/39.12)	ENRMPHPQSTeyKNSQLQQHLLNSQypyNNPNQG
 1490- 1518 (56.51/32.52)	EGRPDHGQVP..RSEGVPSHMMPSQ...KMPQMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.92|      30|      35|      26|      57|       9
---------------------------------------------------------------------------
   26-   57 (49.52/30.72)	ISECERLF.HIIYKYltSKSLEHLF.QENLDFIE
   64-   95 (46.40/23.51)	IIECYRLLeHMSDND..KRGLALKFcIENLQMCE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.52|      18|      47|    1267|    1284|      10
---------------------------------------------------------------------------
 1267- 1284 (31.12/20.22)	ESQLLYTARI..ILPFIVKM
 1315- 1334 (28.40/17.74)	ETPIVYKSLIcdIMYFIKYM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.44|      29|      41|     828|     868|      12
---------------------------------------------------------------------------
  770-  826 (40.39/16.38)	IAKHLYNNPE.DLNsqmtiednnlnmlidlinndpllkeikfPEEY..LSKYRDK.YILFC
  828-  860 (44.05/50.28)	IFKFLEDNPDaEFN............................PCFYkiLTHFNPKeIVLLC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05287 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQLPQVYENIINKSDTTENRMPHPQSTEYKNSQLQQHLLNSQYPYNNPNQGNVLNANQRLQMEGRPDHGQVPRSEGVPSHMMPSQKMPQMGMPPNQNVGSQIPMQPGQNMFPGDPRLQQDIRMQQKQQAFQHQYNLHQSMQNKQQMSHQSNVNQSTNQPMNPYNNPSQYHNVMHGQGIPYNQHMPGKQQQIQPPPGMGPNFNMPPGMNMYNNTQQYPPNMMHHPGMGMHPGVQNPHNIPQQGISPIYPQGHMYQGMPTQQQYPPSHLQGHGYNQQRM
1428
1704










Molecular Recognition Features






MoRF SequenceStartStop




NANANA